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PubMed code 11374954

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phospholipase A2


(Apis mellifera)		BDBM50269843
PNG
(Bolinaquinone | CHEMBL477692)
Show SMILES COC1=CC(=O)C(=O)C(C[C@@]2(C)CC[C@@]3(C)[C@@H](CCC=C3C)[C@H]2C)C1=O |r,c:19,t:2|
Show InChI InChI=1S/C22H30O4/c1-13-7-6-8-16-14(2)21(3,9-10-22(13,16)4)12-15-19(24)17(23)11-18(26-5)20(15)25/h7,11,14-16H,6,8-10,12H2,1-5H3/t14-,15?,16+,21-,22-/m1/s1
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n/an/a 100n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50269843
PNG
(Bolinaquinone | CHEMBL477692)
Show SMILES COC1=CC(=O)C(=O)C(C[C@@]2(C)CC[C@@]3(C)[C@@H](CCC=C3C)[C@H]2C)C1=O |r,c:19,t:2|
Show InChI InChI=1S/C22H30O4/c1-13-7-6-8-16-14(2)21(3,9-10-22(13,16)4)12-15-19(24)17(23)11-18(26-5)20(15)25/h7,11,14-16H,6,8-10,12H2,1-5H3/t14-,15?,16+,21-,22-/m1/s1
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n/an/a 200n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50269843
PNG
(Bolinaquinone | CHEMBL477692)
Show SMILES COC1=CC(=O)C(=O)C(C[C@@]2(C)CC[C@@]3(C)[C@@H](CCC=C3C)[C@H]2C)C1=O |r,c:19,t:2|
Show InChI InChI=1S/C22H30O4/c1-13-7-6-8-16-14(2)21(3,9-10-22(13,16)4)12-15-19(24)17(23)11-18(26-5)20(15)25/h7,11,14-16H,6,8-10,12H2,1-5H3/t14-,15?,16+,21-,22-/m1/s1
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n/an/a 400n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of pig pancreatic group 1 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50269844
PNG
(CHEMBL517216 | Dysidine)
Show SMILES C[C@@H]1[C@@H]2CCC=C(C)[C@@]2(C)CC[C@]1(C)Cc1c(O)c(O)cc(N=CCS(O)(=O)=O)c1O |r,w:22.23,t:5|
Show InChI InChI=1S/C23H33NO6S/c1-14-6-5-7-17-15(2)22(3,8-9-23(14,17)4)13-16-20(26)18(12-19(25)21(16)27)24-10-11-31(28,29)30/h6,10,12,15,17,25-27H,5,7-9,11,13H2,1-4H3,(H,28,29,30)/t15-,17+,22-,23-/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2, membrane associated


(Homo sapiens (Human))		BDBM50250399
PNG
(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/CCC1=CC[C@@H](O[C@H]1O)C1=CC(=O)O[C@H]1O |r,c:4,t:17,25|
Show InChI InChI=1S/C25H36O5/c1-16(10-12-20-17(2)8-6-14-25(20,3)4)7-5-9-18-11-13-21(29-23(18)27)19-15-22(26)30-24(19)28/h7,11,15,21,23-24,27-28H,5-6,8-10,12-14H2,1-4H3/b16-7+/t21-,23-,24-/m1/s1
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n/an/a 3.90E+3n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2


(Apis mellifera)		BDBM50250399
PNG
(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/CCC1=CC[C@@H](O[C@H]1O)C1=CC(=O)O[C@H]1O |r,c:4,t:17,25|
Show InChI InChI=1S/C25H36O5/c1-16(10-12-20-17(2)8-6-14-25(20,3)4)7-5-9-18-11-13-21(29-23(18)27)19-15-22(26)30-24(19)28/h7,11,15,21,23-24,27-28H,5-6,8-10,12-14H2,1-4H3/b16-7+/t21-,23-,24-/m1/s1
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n/an/a 7.50E+3n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%