BindingDB logo
myBDB logout

PubMed code 14667218

Compile data set for download or QSAR
Found 75 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50154716
PNG
((-)-1-Methyl-4-(8-methylsulfanyl-10,11-dihydro-dib...)
Show SMILES CSc1ccc2Sc3ccccc3C[C@H](N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3/t18-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Similars
Article
PubMed
 1n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r|
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.30n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403759
PNG
(CHEMBL428494)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccn1)c23
Show InChI InChI=1S/C24H30N4O/c29-23-24(12-6-8-19-7-5-9-20(26-23)22(19)24)11-2-4-14-27-15-17-28(18-16-27)21-10-1-3-13-25-21/h1,3,5,7,9-10,13H,2,4,6,8,11-12,14-18H2,(H,26,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474439
PNG
(CHEMBL347286)
Show SMILES CC1CCN(CC[C@@H]2CCCN2S(=O)(=O)c2cccc(Br)c2)CC1
Show InChI InChI=1S/C18H27BrN2O2S/c1-15-7-11-20(12-8-15)13-9-17-5-3-10-21(17)24(22,23)18-6-2-4-16(19)14-18/h2,4,6,14-15,17H,3,5,7-13H2,1H3/t17-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50116963
PNG
(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCC(=CC1)c1ccccc1)c23 |c:20|
Show InChI InChI=1S/C26H30N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12-13H,4-5,7,11,14-19H2,(H,27,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 2n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50130279
PNG
((R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidi...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(C)c2)CC1
Show InChI InChI=1S/C19H30N2O2S/c1-16-8-12-20(13-9-16)14-10-18-6-4-11-21(18)24(22,23)19-7-3-5-17(2)15-19/h3,5,7,15-16,18H,4,6,8-14H2,1-2H3/t18-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403770
PNG
(CHEMBL12427)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C25H31N3O/c29-24-25(14-7-9-20-8-6-12-22(26-24)23(20)25)13-4-5-15-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h1-3,6,8,10-12H,4-5,7,9,13-19H2,(H,26,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403768
PNG
(CHEMBL273246)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)c1ccccc1C#N)c23
Show InChI InChI=1S/C26H30N4O/c27-19-21-7-1-2-11-23(21)30-17-15-29(16-18-30)14-4-3-12-26-13-6-9-20-8-5-10-22(24(20)26)28-25(26)31/h1-2,5,7-8,10-11H,3-4,6,9,12-18H2,(H,28,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50098549
PNG
((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 |wD:10.11,(21.5,-8.8,;21.5,-7.27,;22.84,-6.51,;22.87,-4.98,;21.53,-4.21,;21.56,-2.65,;20.23,-1.86,;18.86,-2.62,;18.86,-4.18,;20.19,-4.98,;20.19,-6.51,;18.86,-7.27,;17.55,-6.51,;16.21,-7.27,;14.91,-6.51,;14.91,-4.98,;16.21,-4.18,;16.18,-2.49,;14.78,-1.86,;13.54,-2.72,;14.66,-.33,;15.93,.56,;17.3,-.11,;17.42,-1.63,;18.76,-.84,;20.07,-.07,;17.55,-4.95,)|
Show InChI InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor was determined using [3H]5-HT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474438
PNG
(CHEMBL153398)
Show SMILES CC1CCN(CC[C@@H]2CCCN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C18H26Cl2N2O2S/c1-14-6-10-21(11-7-14)12-8-15-3-2-9-22(15)25(23,24)16-4-5-17(19)18(20)13-16/h4-5,13-15H,2-3,6-12H2,1H3/t15-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50130272
PNG
(2a-[3-(4-Phenyl-piperazin-1-yl)-propyl]-2a,3,4,5-t...)
Show SMILES O=C1Nc2cccc3CCCC1(CCCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C24H29N3O/c28-23-24(12-5-8-19-7-4-11-21(25-23)22(19)24)13-6-14-26-15-17-27(18-16-26)20-9-2-1-3-10-20/h1-4,7,9-11H,5-6,8,12-18H2,(H,25,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403777
PNG
(CHEMBL12702)
Show SMILES COc1ccccc1N1CCN(CCCCC23CCCc4cccc(NC2=O)c34)CC1
Show InChI InChI=1S/C26H33N3O2/c1-31-23-12-3-2-11-22(23)29-18-16-28(17-19-29)15-5-4-13-26-14-7-9-20-8-6-10-21(24(20)26)27-25(26)30/h2-3,6,8,10-12H,4-5,7,9,13-19H2,1H3,(H,27,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM30704
PNG
((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13
Show InChI InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 6.30n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50024204
PNG
(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Show SMILES CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1
Show InChI InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 7.90n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474442
PNG
(CHEMBL153156)
Show SMILES COc1cccc(c1)S(=O)(=O)N1CCC[C@H]1CCN1CCC(C)CC1
Show InChI InChI=1S/C19H30N2O3S/c1-16-8-12-20(13-9-16)14-10-17-5-4-11-21(17)25(22,23)19-7-3-6-18(15-19)24-2/h3,6-7,15-17H,4-5,8-14H2,1-2H3/t17-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 10n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50130289
PNG
((S)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrr...)
Show SMILES CC1CCN(CC[C@@H]2CCCN2S(=O)(=O)c2cccc3ccccc23)CC1
Show InChI InChI=1S/C22H30N2O2S/c1-18-11-15-23(16-12-18)17-13-20-8-5-14-24(20)27(25,26)22-10-4-7-19-6-2-3-9-21(19)22/h2-4,6-7,9-10,18,20H,5,8,11-17H2,1H3/t20-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 10n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50130269
PNG
((6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-i...)
Show SMILES CCN(CC)C(=O)[C@H]1CN(C)[C@@H]2Cc3c(Br)[nH]c4cccc(C2=C1)c34 |c:23|
Show InChI InChI=1S/C20H24BrN3O/c1-4-24(5-2)20(25)12-9-14-13-7-6-8-16-18(13)15(19(21)22-16)10-17(14)23(3)11-12/h6-9,12,17,22H,4-5,10-11H2,1-3H3/t12-,17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 10n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50469883
PNG
(CHEBI:584020 | Deseril | Methysergide)
Show SMILES [H][C@@]12Cc3cn(C)c4cccc(C1=C[C@H](CN2C)C(=O)NC(CC)CO)c34 |c:13|
Show InChI InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15?,19-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50098546
PNG
((R)-11-(2,6-Dimethoxy-phenyl)-6-methyl-5,6,6a,7-te...)
Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 |wD:16.17,(7.32,-7.03,;8.71,-7.68,;9.98,-6.81,;9.85,-5.28,;11.11,-4.41,;12.5,-5.06,;12.63,-6.59,;14.14,-6.11,;14.33,-4.57,;11.35,-7.46,;11.39,-9.18,;10.07,-9.94,;10.07,-11.48,;11.39,-12.25,;12.73,-11.48,;14.07,-12.25,;15.39,-11.48,;16.72,-12.25,;16.7,-13.78,;18.06,-11.49,;18.06,-9.94,;16.75,-9.18,;16.75,-7.62,;15.41,-6.84,;14.07,-7.61,;14.07,-9.15,;15.41,-9.94,;12.73,-9.94,)|
Show InChI InChI=1S/C25H25NO2/c1-26-14-13-16-7-4-9-18-23-17(15-20(26)24(16)18)8-5-10-19(23)25-21(27-2)11-6-12-22(25)28-3/h4-12,20H,13-15H2,1-3H3/t20-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor was determined using [3H]5-HT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
DrugBank
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474444
PNG
(CHEMBL152595)
Show SMILES CC1CCN(CC[C@@H]2CCCCN2S(=O)(=O)c2cccc3ccccc23)CC1
Show InChI InChI=1S/C23H32N2O2S/c1-19-12-16-24(17-13-19)18-14-21-9-4-5-15-25(21)28(26,27)23-11-6-8-20-7-2-3-10-22(20)23/h2-3,6-8,10-11,19,21H,4-5,9,12-18H2,1H3/t21-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 16n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474459
PNG
(CHEMBL154090)
Show SMILES C[C@H](CCN1CCC(C)CC1)C(C)S(=O)(=O)c1cc(Br)c(Br)cc1-c1cccs1
Show InChI InChI=1S/C22H29Br2NO2S2/c1-15-6-9-25(10-7-15)11-8-16(2)17(3)29(26,27)22-14-20(24)19(23)13-18(22)21-5-4-12-28-21/h4-5,12-17H,6-11H2,1-3H3/t16-,17?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 16n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50001775
PNG
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1
Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 16n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474466
PNG
(CHEMBL152292)
Show SMILES C[C@H](CCN1CCC(C)CC1)C(C)S(=O)(=O)c1ccc(Br)c(Br)c1
Show InChI InChI=1S/C18H27Br2NO2S/c1-13-6-9-21(10-7-13)11-8-14(2)15(3)24(22,23)16-4-5-17(19)18(20)12-16/h4-5,12-15H,6-11H2,1-3H3/t14-,15?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM21397
PNG
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 20n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50098544
PNG
((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2O)c-31 |wD:10.11,(3.15,-8.39,;3.15,-6.86,;4.49,-6.09,;4.51,-4.55,;3.18,-3.79,;3.2,-2.22,;1.86,-1.42,;.49,-2.19,;.49,-3.75,;1.83,-4.55,;1.83,-6.09,;.49,-6.86,;-.83,-6.09,;-2.17,-6.86,;-3.49,-6.09,;-3.49,-4.55,;-2.17,-3.75,;-2.21,-2.06,;-3.61,-1.42,;-4.85,-2.28,;-3.73,.12,;-2.45,1.01,;-1.08,.34,;-.95,-1.19,;.38,-.39,;-.83,-4.52,)|
Show InChI InChI=1S/C24H23NO/c1-15-6-3-11-21(26)22(15)18-9-5-8-17-14-20-24-16(12-13-25(20)2)7-4-10-19(24)23(17)18/h3-11,20,26H,12-14H2,1-2H3/t20-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 25n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor was determined using [3H]5-HT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474440
PNG
(CHEMBL347115)
Show SMILES C[C@H](CCN1CCC(C)CC1)C(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31NO2S/c1-17-11-14-23(15-12-17)16-13-18(2)19(3)26(24,25)22-10-6-8-20-7-4-5-9-21(20)22/h4-10,17-19H,11-16H2,1-3H3/t18-,19?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r|
Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50098550
PNG
(3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin...)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474465
PNG
(CHEMBL422146)
Show SMILES C[C@H](CCN1CCC(C)CC1)C(C)S(=O)(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C18H27Cl2NO2S/c1-13-6-9-21(10-7-13)11-8-14(2)15(3)24(22,23)16-4-5-17(19)18(20)12-16/h4-5,12-15H,6-11H2,1-3H3/t14-,15?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 32n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50017721
PNG
(1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...)
Show SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]=[#6]-c2ccccc-12 |c:16|
Show InChI InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
 50n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50116963
PNG
(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCC(=CC1)c1ccccc1)c23 |c:20|
Show InChI InChI=1S/C26H30N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12-13H,4-5,7,11,14-19H2,(H,27,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 50n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403764
PNG
(CHEMBL276206)
Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C26H29N3O2/c1-31-24-13-3-2-11-22(24)28-18-16-27(17-19-28)14-4-5-15-29-23-12-7-9-20-8-6-10-21(25(20)23)26(29)30/h2-3,6-13H,4-5,14-19H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50366495
PNG
((+)butaclamol | CHEMBL1255588)
Show SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 |r|
Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50222218
PNG
(CHEBI:51137 | Mianserin)
Show SMILES CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 63n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptor

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50098550
PNG
(3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin...)
Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 79n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50240359
PNG
(1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...)
Show SMILES O=C1N(CCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H29N3O/c30-26-23-13-7-9-21-10-8-14-24(25(21)23)29(26)16-6-2-5-15-27-17-19-28(20-18-27)22-11-3-1-4-12-22/h1,3-4,7-14H,2,5-6,15-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 79n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403774
PNG
(CHEMBL273982)
Show SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C27H31N3O2/c1-32-25-14-4-3-12-23(25)29-19-17-28(18-20-29)15-5-2-6-16-30-24-13-8-10-21-9-7-11-22(26(21)24)27(30)31/h3-4,7-14H,2,5-6,15-20H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 100n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403772
PNG
(CHEMBL268921)
Show SMILES O=C1Nc2cccc3CCCC1(CCN1CCN(CC1)c1ccccc1)c23
Show InChI InChI=1S/C23H27N3O/c27-22-23(11-5-7-18-6-4-10-20(24-22)21(18)23)12-13-25-14-16-26(17-15-25)19-8-2-1-3-9-19/h1-4,6,8-10H,5,7,11-17H2,(H,24,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 100n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474461
PNG
(CHEMBL152873)
Show SMILES C[C@H](CCN1CCC[C@@H](C)C1)C(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31NO2S/c1-17-8-7-14-23(16-17)15-13-18(2)19(3)26(24,25)22-12-6-10-20-9-4-5-11-21(20)22/h4-6,9-12,17-19H,7-8,13-16H2,1-3H3/t17-,18-,19?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 126n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403779
PNG
(CHEMBL13032)
Show SMILES COc1ccccc1N1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C25H29N3O3S/c1-31-23-12-3-2-10-21(23)27-18-16-26(17-19-27)14-4-5-15-28-22-11-6-8-20-9-7-13-24(25(20)22)32(28,29)30/h2-3,6-13H,4-5,14-19H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403778
PNG
(CHEMBL12933)
Show SMILES O=S1(=O)N(CCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C25H29N3O2S/c29-31(30)24-14-8-10-21-9-7-13-23(25(21)24)28(31)16-6-2-5-15-26-17-19-27(20-18-26)22-11-3-1-4-12-22/h1,3-4,7-14H,2,5-6,15-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403763
PNG
(CHEMBL12908)
Show SMILES COc1ccccc1N1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C27H33N3O3S/c1-33-25-14-5-4-12-23(25)29-20-18-28(19-21-29)16-6-2-3-7-17-30-24-13-8-10-22-11-9-15-26(27(22)24)34(30,31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403762
PNG
(CHEMBL273452)
Show SMILES CC(C)C1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C23H30N2O/c1-17(2)18-11-15-24(16-12-18)13-3-4-14-25-21-10-6-8-19-7-5-9-20(22(19)21)23(25)26/h5-10,17-18H,3-4,11-16H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 200n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403784
PNG
(CHEMBL430280)
Show SMILES COc1ccccc1N1CCN(CCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C26H31N3O3S/c1-32-24-13-4-3-11-22(24)28-19-17-27(18-20-28)15-5-2-6-16-29-23-12-7-9-21-10-8-14-25(26(21)23)33(29,30)31/h3-4,7-14H,2,5-6,15-20H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 251n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474455
PNG
(CHEMBL346906)
Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C25H27N3O2/c1-30-23-12-3-2-10-21(23)27-17-15-26(16-18-27)13-6-14-28-22-11-5-8-19-7-4-9-20(24(19)22)25(28)29/h2-5,7-12H,6,13-18H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 398n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474447
PNG
(CHEMBL151858)
Show SMILES C[C@H](CCN1CCC[C@H](C)C1)C(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31NO2S/c1-17-8-7-14-23(16-17)15-13-18(2)19(3)26(24,25)22-12-6-10-20-9-4-5-11-21(20)22/h4-6,9-12,17-19H,7-8,13-16H2,1-3H3/t17-,18+,19?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 631n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474446
PNG
(CHEMBL153132)
Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C25H27N3O/c29-25-22-12-6-8-20-9-7-13-23(24(20)22)28(25)15-5-4-14-26-16-18-27(19-17-26)21-10-2-1-3-11-21/h1-3,6-13H,4-5,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 631n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474449
PNG
(CHEMBL358408)
Show SMILES O=C1N(CCCCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 |c:11|
Show InChI InChI=1S/C27H28N2O/c30-27-24-13-7-11-23-12-8-14-25(26(23)24)29(27)18-6-2-5-17-28-19-15-22(16-20-28)21-9-3-1-4-10-21/h1,3-4,7-15H,2,5-6,16-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474451
PNG
(CHEMBL440003)
Show SMILES CC(C)C1CCN(CCCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C24H32N2O/c1-18(2)19-12-16-25(17-13-19)14-4-3-5-15-26-22-11-7-9-20-8-6-10-21(23(20)22)24(26)27/h6-11,18-19H,3-5,12-17H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474456
PNG
(CHEMBL151405)
Show SMILES O=C1N(CCCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 |c:10|
Show InChI InChI=1S/C26H26N2O/c29-26-23-12-6-10-22-11-7-13-24(25(22)23)28(26)17-5-4-16-27-18-14-21(15-19-27)20-8-2-1-3-9-20/h1-3,6-14H,4-5,15-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474463
PNG
(CHEMBL346191)
Show SMILES O=S1(=O)N(CCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C24H27N3O2S/c28-30(29)23-13-7-9-20-8-6-12-22(24(20)23)27(30)15-5-4-14-25-16-18-26(19-17-25)21-10-2-1-3-11-21/h1-3,6-13H,4-5,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474460
PNG
(CHEMBL152309)
Show SMILES O=S1(=O)N(CCCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H31N3O2S/c30-32(31)25-15-9-11-22-10-8-14-24(26(22)25)29(32)17-7-2-1-6-16-27-18-20-28(21-19-27)23-12-4-3-5-13-23/h3-5,8-15H,1-2,6-7,16-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474464
PNG
(CHEMBL152853)
Show SMILES COc1ccccc1N1CCN(CCCCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C28H33N3O2/c1-33-26-15-5-4-13-24(26)30-20-18-29(19-21-30)16-6-2-3-7-17-31-25-14-9-11-22-10-8-12-23(27(22)25)28(31)32/h4-5,8-15H,2-3,6-7,16-21H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474458
PNG
(CHEMBL347728)
Show SMILES O=C1N(CCCCN2CCC(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H28N2O/c29-26-23-12-6-10-22-11-7-13-24(25(22)23)28(26)17-5-4-16-27-18-14-21(15-19-27)20-8-2-1-3-9-20/h1-3,6-13,21H,4-5,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403781
PNG
(CHEMBL275495)
Show SMILES CC1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C21H26N2O/c1-16-10-14-22(15-11-16)12-2-3-13-23-19-9-5-7-17-6-4-8-18(20(17)19)21(23)24/h4-9,16H,2-3,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474436
PNG
(CHEMBL152042)
Show SMILES O=C1N(CCCCCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C27H31N3O/c31-27-24-14-8-10-22-11-9-15-25(26(22)24)30(27)17-7-2-1-6-16-28-18-20-29(21-19-28)23-12-4-3-5-13-23/h3-5,8-15H,1-2,6-7,16-21H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474437
PNG
(CHEMBL356662)
Show SMILES O=C1N(CCCCN2CCC(CC2)C2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H34N2O/c29-26-23-12-6-10-22-11-7-13-24(25(22)23)28(26)17-5-4-16-27-18-14-21(15-19-27)20-8-2-1-3-9-20/h6-7,10-13,20-21H,1-5,8-9,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474450
PNG
(CHEMBL347511)
Show SMILES C[C@@H](CCN1CCC[C@@H](C)C1)C(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31NO2S/c1-17-8-7-14-23(16-17)15-13-18(2)19(3)26(24,25)22-12-6-10-20-9-4-5-11-21(20)22/h4-6,9-12,17-19H,7-8,13-16H2,1-3H3/t17-,18+,19?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.59E+3n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403767
PNG
(CHEMBL12535)
Show SMILES CN1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C19H25N3O2S/c1-20-12-14-21(15-13-20)10-2-3-11-22-17-8-4-6-16-7-5-9-18(19(16)17)25(22,23)24/h4-9H,2-3,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474445
PNG
(CHEMBL152483)
Show SMILES O=C1N(CCCCCN2CCN(CC2)C2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H35N3O/c30-26-23-13-7-9-21-10-8-14-24(25(21)23)29(26)16-6-2-5-15-27-17-19-28(20-18-27)22-11-3-1-4-12-22/h7-10,13-14,22H,1-6,11-12,15-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403761
PNG
(CHEMBL12656)
Show SMILES CC1CCN(CCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C21H28N2O2S/c1-17-11-15-22(16-12-17)13-3-2-4-14-23-19-9-5-7-18-8-6-10-20(21(18)19)26(23,24)25/h5-10,17H,2-4,11-16H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403786
PNG
(CHEMBL273385)
Show SMILES CN1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C20H25N3O/c1-21-12-14-22(15-13-21)10-2-3-11-23-18-9-5-7-16-6-4-8-17(19(16)18)20(23)24/h4-9H,2-3,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403785
PNG
(CHEMBL12868)
Show SMILES CC1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C20H26N2O2S/c1-16-10-14-21(15-11-16)12-2-3-13-22-18-8-4-6-17-7-5-9-19(20(17)18)25(22,23)24/h4-9,16H,2-3,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474443
PNG
(CHEMBL152029)
Show SMILES CC1CCN(CCCCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1
Show InChI InChI=1S/C22H30N2O2S/c1-18-12-16-23(17-13-18)14-4-2-3-5-15-24-20-10-6-8-19-9-7-11-21(22(19)20)27(24,25)26/h6-11,18H,2-5,12-17H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474457
PNG
(CHEMBL152421)
Show SMILES O=C1N(CN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C22H21N3O/c26-22-19-10-4-6-17-7-5-11-20(21(17)19)25(22)16-23-12-14-24(15-13-23)18-8-2-1-3-9-18/h1-11H,12-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474453
PNG
(CHEMBL356653)
Show SMILES O=C1N(CCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23
Show InChI InChI=1S/C24H25N3O/c28-24-21-11-4-7-19-8-5-12-22(23(19)21)27(24)14-6-13-25-15-17-26(18-16-25)20-9-2-1-3-10-20/h1-5,7-12H,6,13-18H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474448
PNG
(CHEMBL357800)
Show SMILES O=S1(=O)N(CCCCCN2CCC(CC2)C2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C26H36N2O2S/c29-31(30)25-14-8-12-23-11-7-13-24(26(23)25)28(31)18-6-2-5-17-27-19-15-22(16-20-27)21-9-3-1-4-10-21/h7-8,11-14,21-22H,1-6,9-10,15-20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403782
PNG
(CHEMBL268973)
Show SMILES O=C1N(CCCCN2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C20H24N2O/c23-20-17-10-6-8-16-9-7-11-18(19(16)17)22(20)15-5-4-14-21-12-2-1-3-13-21/h6-11H,1-5,12-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474462
PNG
(CHEMBL155395)
Show SMILES O=C1N(CCCCN2CCN(CC2)C2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C25H33N3O/c29-25-22-12-6-8-20-9-7-13-23(24(20)22)28(25)15-5-4-14-26-16-18-27(19-17-26)21-10-2-1-3-11-21/h6-9,12-13,21H,1-5,10-11,14-19H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474441
PNG
(CHEMBL347208)
Show SMILES O=C1N(CCCCSc2ncc[nH]2)c2cccc3cccc1c23
Show InChI InChI=1S/C18H17N3OS/c22-17-14-7-3-5-13-6-4-8-15(16(13)14)21(17)11-1-2-12-23-18-19-9-10-20-18/h3-10H,1-2,11-12H2,(H,19,20)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50474452
PNG
(CHEMBL152503)
Show SMILES COc1ccccc1N1CCN(CN2C(=O)c3cccc4cccc2c34)CC1
Show InChI InChI=1S/C23H23N3O2/c1-28-21-11-3-2-9-19(21)25-14-12-24(13-15-25)16-26-20-10-5-7-17-6-4-8-18(22(17)20)23(26)27/h2-11H,12-16H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Rattus norvegicus (rat))		BDBM50403776
PNG
(CHEMBL275333)
Show SMILES O=S1(=O)N(CCCCN2CCCCC2)c2cccc3cccc1c23
Show InChI InChI=1S/C19H24N2O2S/c22-24(23)18-11-7-9-16-8-6-10-17(19(16)18)21(24)15-5-4-14-20-12-2-1-3-13-20/h6-11H,1-5,12-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine receptor 7 on rat hypothalamus membranes using [3H]5-CT as radioligand.

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50474454
PNG
(CHEMBL345971)
Show SMILES C[C@@H](CCN1CCC[C@H](C)C1)C(C)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31NO2S/c1-17-8-7-14-23(16-17)15-13-18(2)19(3)26(24,25)22-12-6-10-20-9-4-5-11-21(20)22/h4-6,9-12,17-19H,7-8,13-16H2,1-3H3/t17-,18-,19?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.00E+5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human 5-hydroxytryptamine 7 receptor was determined in HEK293 cells using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))		BDBM50403783
PNG
(CHEMBL273890)
Show SMILES O=C1Nc2cccc3CCCC1(CCCCN1CCN(CC1)C1CCCCC1)c23
Show InChI InChI=1S/C25H37N3O/c29-24-25(14-7-9-20-8-6-12-22(26-24)23(20)25)13-4-5-15-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h6,8,12,21H,1-5,7,9-11,13-19H2,(H,26,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 1.00E+5n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity towards human recombinant 5-hydroxytryptamine 7 receptor was determined using [3H]5-CT as radioligand

J Med Chem 46: 5638-50 (2003)


Article DOI: 10.1021/jm030841r
BindingDB Entry DOI: 10.7270/Q29W0J74
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%