Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32447 (Benzo[c][2,7]naphthyridine, 39) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32435 (Benzo[c][2,7]naphthyridine, 28) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32450 (Benzo[c][2,7]naphthyridine, 42) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32430 (Benzo[c][2,7]naphthyridine, 24) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32433 (Benzo[c][2,7]naphthyridine, 14) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32444 (Benzo[c][2,7]naphthyridine, 36) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32449 (Benzo[c][2,7]naphthyridine, 41) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32436 (Benzo[c][2,7]naphthyridine, 29) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32437 (Benzo[c][2,7]naphthyridine, 30) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32427 (Benzo[c][2,7]naphthyridine, 21) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32445 (Benzo[c][2,7]naphthyridine, 37) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32422 (Benzo[c][2,7]naphthyridine, 9) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32431 (Benzo[c][2,7]naphthyridine, 25) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 74 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32441 (Benzo[c][2,7]naphthyridine, 33) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32448 (Benzo[c][2,7]naphthyridine, 40) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32428 (Benzo[c][2,7]naphthyridine, 22) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >100 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32425 (Benzo[c][2,7]naphthyridine, 12) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32423 (Benzo[c][2,7]naphthyridine, 10) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32446 (Benzo[c][2,7]naphthyridine, 38) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 142 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32434 (Benzo[c][2,7]naphthyridine, 27) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 144 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32432 (Benzo[c][2,7]naphthyridine, 26) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32440 (Benzo[c][2,7]naphthyridine, 32) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 283 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32443 (Benzo[c][2,7]naphthyridine, 35) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32442 (Benzo[c][2,7]naphthyridine, 34) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 434 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32451 (Benzo[c][2,7]naphthyridine, 43) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 505 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32438 (Benzo[c][2,7]naphthyridine, 31) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 532 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32418 (Benzo[c][2,7]naphthyridine, 5) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 739 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32452 (Benzo[c][2,7]naphthyridine, 44) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32439 (Benzo[c][2,7]naphthyridine, 16) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32426 (Benzo[c][2,7]naphthyridine, 15) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32420 (Benzo[c][2,7]naphthyridine, 7) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32424 (Benzo[c][2,7]naphthyridine, 11) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32421 (Benzo[c][2,7]naphthyridine, 8) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32429 (Benzo[c][2,7]naphthyridine, 23) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.92E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 [48-359] (Homo sapiens (Human)) | BDBM32419 (Benzo[c][2,7]naphthyridine, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.49E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Wyeth Research | Assay Description A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti... | Bioorg Med Chem Lett 19: 5225-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.007 BindingDB Entry DOI: 10.7270/Q2XK8CXJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |