Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416756
(CHEMBL1242518)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C19H20ClN5O2S2/c1-2-23-8-4-5-13(11-23)25-12-15(14-6-3-7-21-17(14)25)29(26,27)18-16(20)22-19-24(18)9-10-28-19/h3,6-7,9-10,12-13H,2,4-5,8,11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416755
(CHEMBL1242425)Show SMILES Clc1nc2sccn2c1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 Show InChI InChI=1S/C17H16ClN5O2S2/c18-14-16(22-7-8-26-17(22)21-14)27(24,25)13-10-23(11-3-1-5-19-9-11)15-12(13)4-2-6-20-15/h2,4,6-8,10-11,19H,1,3,5,9H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.708 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416753
(CHEMBL1242703)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C17H16ClN5O2S2/c1-21-6-4-11(9-21)23-10-13(12-3-2-5-19-15(12)23)27(24,25)16-14(18)20-17-22(16)7-8-26-17/h2-3,5,7-8,10-11H,4,6,9H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217891
(3-(3-bromo-benzenesulfonyl)-1-(1-methyl-pyrrolidin...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:4.6| Show InChI InChI=1S/C18H18BrN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.891 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416752
(CHEMBL1242702)Show SMILES Clc1nc2sccn2c1S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 Show InChI InChI=1S/C16H14ClN5O2S2/c17-13-15(21-6-7-25-16(21)20-13)26(23,24)12-9-22(10-3-5-18-8-10)14-11(12)2-1-4-19-14/h1-2,4,6-7,9-10,18H,3,5,8H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416751
(CHEMBL1242614)Show InChI InChI=1S/C15H14ClN3O2S2/c16-13-3-4-14(22-13)23(20,21)12-9-19(10-5-7-17-8-10)15-11(12)2-1-6-18-15/h1-4,6,9-10,17H,5,7-8H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217883
(3-[(5-chlorothien-2-yl)sulfonyl]-1-piperidin-3-yl-...)Show SMILES Clc1ccc(s1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:12.12| Show InChI InChI=1S/C16H16ClN3O2S2/c17-14-5-6-15(23-14)24(21,22)13-10-20(11-3-1-7-18-9-11)16-12(13)4-2-8-19-16/h2,4-6,8,10-11,18H,1,3,7,9H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217920
(3-(3-bromo-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpy...)Show SMILES Brc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16BrN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217893
(1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...)Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:16.16| Show InChI InChI=1S/C18H16F3N3O2S/c19-18(20,21)12-3-1-4-14(9-12)27(25,26)16-11-24(13-6-8-22-10-13)17-15(16)5-2-7-23-17/h1-5,7,9,11,13,22H,6,8,10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217916
(3-[(3-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)Show SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18ClN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217925
(3-(3-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416754
(CHEMBL1242791)Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C18H18ClN5O2S2/c1-2-22-7-5-12(10-22)24-11-14(13-4-3-6-20-16(13)24)28(25,26)17-15(19)21-18-23(17)8-9-27-18/h3-4,6,8-9,11-12H,2,5,7,10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217880
(3-(3-chloro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)Show SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16ClN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217924
(3-(3-chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416757
(CHEMBL1242615)Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C20H22ClN5O2S2/c1-13(2)24-8-4-5-14(11-24)26-12-16(15-6-3-7-22-18(15)26)30(27,28)19-17(21)23-20-25(19)9-10-29-20/h3,6-7,9-10,12-14H,4-5,8,11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217890
(3-[(5-chlorothien-2-yl)sulfonyl]-1-(1-methylpiperi...)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:5.7| Show InChI InChI=1S/C17H18ClN3O2S2/c1-20-9-3-4-12(10-20)21-11-14(13-5-2-8-19-17(13)21)25(22,23)16-7-6-15(18)24-16/h2,5-8,11-12H,3-4,9-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50416758
(CHEMBL1242517)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C18H18ClN5O2S2/c1-22-7-3-4-12(10-22)24-11-14(13-5-2-6-20-16(13)24)28(25,26)17-15(19)21-18-23(17)8-9-27-18/h2,5-6,8-9,11-12H,3-4,7,10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217918
(3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)Show SMILES Fc1ccccc1S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16FN3O2S/c18-14-5-1-2-6-15(14)24(22,23)16-11-21(12-7-9-19-10-12)17-13(16)4-3-8-20-17/h1-6,8,11-12,19H,7,9-10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217889
(3-[(2-fluorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)Show SMILES Fc1ccccc1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18FN3O2S/c19-15-7-1-2-8-16(15)25(23,24)17-12-22(13-5-3-9-20-11-13)18-14(17)6-4-10-21-18/h1-2,4,6-8,10,12-13,20H,3,5,9,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217903
(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methy...)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(c1)C(F)(F)F |w:5.7| Show InChI InChI=1S/C20H20F3N3O2S/c1-25-10-4-6-15(12-25)26-13-18(17-8-3-9-24-19(17)26)29(27,28)16-7-2-5-14(11-16)20(21,22)23/h2-3,5,7-9,11,13,15H,4,6,10,12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217881
(3-(2-Chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1Cl |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-10-8-13(11-21)22-12-17(14-5-4-9-20-18(14)22)25(23,24)16-7-3-2-6-15(16)19/h2-7,9,12-13H,8,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217884
(3-[(3-fluorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18FN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217906
(3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hp...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1 |w:4.6| Show InChI InChI=1S/C18H19N3O2S/c1-20-11-9-14(12-20)21-13-17(16-8-5-10-19-18(16)21)24(22,23)15-6-3-2-4-7-15/h2-8,10,13-14H,9,11-12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217926
(3-(3-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16FN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217901
(1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-...)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:6.8| Show InChI InChI=1S/C18H20ClN3O2S2/c1-2-21-10-4-5-13(11-21)22-12-15(14-6-3-9-20-18(14)22)26(23,24)17-8-7-16(19)25-17/h3,6-9,12-13H,2,4-5,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217914
(3-(3-chloro-benzenesulfonyl)-1-(1-ethyl-pyrrolidin...)Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217896
(3-[(3-fluorophenyl)sulfonyl]-1-(1-isopropylpiperid...)Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:7.9| Show InChI InChI=1S/C21H24FN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217923
(1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1Hpyr...)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1 |w:6.8| Show InChI InChI=1S/C20H23N3O2S/c1-2-22-13-7-8-16(14-22)23-15-19(18-11-6-12-21-20(18)23)26(24,25)17-9-4-3-5-10-17/h3-6,9-12,15-16H,2,7-8,13-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217887
(3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)Show SMILES Clc1ccccc1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18ClN3O2S/c19-15-7-1-2-8-16(15)25(23,24)17-12-22(13-5-3-9-20-11-13)18-14(17)6-4-10-21-18/h1-2,4,6-8,10,12-13,20H,3,5,9,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217899
(3-[(3-bromophenyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...)Show SMILES Brc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18BrN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217892
(3-[(3,5-dichlorophenyl)sulfonyl]-1-(1-methylpiperi...)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H19Cl2N3O2S/c1-23-7-3-4-15(11-23)24-12-18(17-5-2-6-22-19(17)24)27(25,26)16-9-13(20)8-14(21)10-16/h2,5-6,8-10,12,15H,3-4,7,11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217907
(3-(4-chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)cc1 |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-10-8-14(11-21)22-12-17(16-3-2-9-20-18(16)22)25(23,24)15-6-4-13(19)5-7-15/h2-7,9,12,14H,8,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217930
(3-(4-bromo-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpy...)Show SMILES Brc1ccc(cc1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16BrN3O2S/c18-12-3-5-14(6-4-12)24(22,23)16-11-21(13-7-9-19-10-13)17-15(16)2-1-8-20-17/h1-6,8,11,13,19H,7,9-10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217895
(1-(1-ethylpiperidin-3-yl)-3-[(3-fluorophenyl)sulfo...)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:6.8| Show InChI InChI=1S/C20H22FN3O2S/c1-2-23-11-5-7-16(13-23)24-14-19(18-9-4-10-22-20(18)24)27(25,26)17-8-3-6-15(21)12-17/h3-4,6,8-10,12,14,16H,2,5,7,11,13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217885
(3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...)Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:16.16| Show InChI InChI=1S/C19H18F3N3O2S/c20-19(21,22)13-4-1-6-15(10-13)28(26,27)17-12-25(14-5-2-8-23-11-14)18-16(17)7-3-9-24-18/h1,3-4,6-7,9-10,12,14,23H,2,5,8,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217898
(3-[(3-fluorophenyl)sulfonyl]-1-(1-methylpiperidin-...)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:5.7| Show InChI InChI=1S/C19H20FN3O2S/c1-22-10-4-6-15(12-22)23-13-18(17-8-3-9-21-19(17)23)26(24,25)16-7-2-5-14(20)11-16/h2-3,5,7-9,11,13,15H,4,6,10,12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217888
(3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...)Show SMILES O=S(=O)(c1cn(C2CCCNC2)c2ncccc12)c1ccccc1 |w:6.5| Show InChI InChI=1S/C18H19N3O2S/c22-24(23,15-7-2-1-3-8-15)17-13-21(14-6-4-10-19-12-14)18-16(17)9-5-11-20-18/h1-3,5,7-9,11,13-14,19H,4,6,10,12H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217905
(3-(4-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(F)cc1 |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-10-8-14(11-21)22-12-17(16-3-2-9-20-18(16)22)25(23,24)15-6-4-13(19)5-7-15/h2-7,9,12,14H,8,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.01 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217915
(3-(4-chloro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)Show SMILES Clc1ccc(cc1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16ClN3O2S/c18-12-3-5-14(6-4-12)24(22,23)16-11-21(13-7-9-19-10-13)17-15(16)2-1-8-20-17/h1-6,8,11,13,19H,7,9-10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217911
(3-(2-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...)Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1F |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-10-8-13(11-21)22-12-17(14-5-4-9-20-18(14)22)25(23,24)16-7-3-2-6-15(16)19/h2-7,9,12-13H,8,10-11H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217931
(8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-s...)Show SMILES O=S(=O)(c1cn(C2CCNC2)c2ncccc12)c1cccc2cccnc12 |w:6.5| Show InChI InChI=1S/C20H18N4O2S/c25-27(26,17-7-1-4-14-5-2-9-22-19(14)17)18-13-24(15-8-11-21-12-15)20-16(18)6-3-10-23-20/h1-7,9-10,13,15,21H,8,11-12H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217921
(3-[(3,5-dichlorophenyl)sulfonyl]-1-piperidin-3-yl-...)Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:14.14| Show InChI InChI=1S/C18H17Cl2N3O2S/c19-12-7-13(20)9-15(8-12)26(24,25)17-11-23(14-3-1-5-21-10-14)18-16(17)4-2-6-22-18/h2,4,6-9,11,14,21H,1,3,5,10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217908
(3-[(4-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...)Show SMILES Clc1ccc(cc1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18ClN3O2S/c19-13-5-7-15(8-6-13)25(23,24)17-12-22(14-3-1-9-20-11-14)18-16(17)4-2-10-21-18/h2,4-8,10,12,14,20H,1,3,9,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217882
(1-(1-ethyl-pyrrolidin-3-yl)-3-(3-fluoro-benzenesul...)Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:5.7| Show InChI InChI=1S/C19H20FN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217917
(3-(4-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)Show SMILES Fc1ccc(cc1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16FN3O2S/c18-12-3-5-14(6-4-12)24(22,23)16-11-21(13-7-9-19-10-13)17-15(16)2-1-8-20-17/h1-6,8,11,13,19H,7,9-10H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217929
(3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...)Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:7.9| Show InChI InChI=1S/C21H24BrN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217910
(3-benzenesulfonyl-1-(1-ethyl-pyrrolidin-3-yl)-1Hpy...)Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1 |w:5.7| Show InChI InChI=1S/C19H21N3O2S/c1-2-21-12-10-15(13-21)22-14-18(17-9-6-11-20-19(17)22)25(23,24)16-7-4-3-5-8-16/h3-9,11,14-15H,2,10,12-13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 11.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217912
(3-[(4-chlorophenyl)sulfonyl]-1-(1-isopropylpiperid...)Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)cc1 |w:7.9| Show InChI InChI=1S/C21H24ClN3O2S/c1-15(2)24-12-4-5-17(13-24)25-14-20(19-6-3-11-23-21(19)25)28(26,27)18-9-7-16(22)8-10-18/h3,6-11,14-15,17H,4-5,12-13H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 11.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217919
(3-[(4-chlorophenyl)sulfonyl]-1-(1-methylpiperidin-...)Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)cc1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-22-11-3-4-15(12-22)23-13-18(17-5-2-10-21-19(17)23)26(24,25)16-8-6-14(20)7-9-16/h2,5-10,13,15H,3-4,11-12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217897
(3-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...)Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:16.16| Show InChI InChI=1S/C19H18F3N3O2S/c20-19(21,22)13-5-7-15(8-6-13)28(26,27)17-12-25(14-3-1-9-23-11-14)18-16(17)4-2-10-24-18/h2,4-8,10,12,14,23H,1,3,9,11H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217894
(1-(1-ethylpiperidin-3-yl)-3-[(3,5-dichlorophenyl)-...)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:6.8| Show InChI InChI=1S/C20H21Cl2N3O2S/c1-2-24-8-4-5-16(12-24)25-13-19(18-6-3-7-23-20(18)25)28(26,27)17-10-14(21)9-15(22)11-17/h3,6-7,9-11,13,16H,2,4-5,8,12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50217886
(1-(1-ethylpiperidin-3-yl)-3-[(4-chlorophenyl)sulfo...)Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)cc1 |w:6.8| Show InChI InChI=1S/C20H22ClN3O2S/c1-2-23-12-4-5-16(13-23)24-14-19(18-6-3-11-22-20(18)24)27(25,26)17-9-7-15(21)8-10-17/h3,6-11,14,16H,2,4-5,12-13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Islamic Azad University
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT6 receptor |
Eur J Med Chem 45: 3911-5 (2010)
Article DOI: 10.1016/j.ejmech.2010.05.045
BindingDB Entry DOI: 10.7270/Q27945XK |
More data for this
Ligand-Target Pair | |
Search and Browse
