Affinity Data by PubMed id=20709559

PubMed code 20709559

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to adrenergic Alpha-2C receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to dopamine D5 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha2A receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha2B receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to dopamine D3 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to 5HT7 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to adrenergic alpha1A receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to dopamine D2 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to adrenergic kappa opioid receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to 5HT3 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.65E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity to dopamine D4 receptor				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50325821 ((6aR,12bR)-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human D1 receptor assessed as cAMP accumulation				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50325822 (CHEMBL1224527 \| trans-(5R)-5-phenyl-1,2,3,4,4a,5,6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.640	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human D1 receptor assessed as cAMP accumulation				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human D1 receptor assessed as cAMP accumulation				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50325820 (CHEMBL1224528 \| dihydroxidine) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human D1 receptor assessed as cAMP accumulation				Bioorg Med Chem 18: 6763-70 (2010) Article DOI: 10.1016/j.bmc.2010.07.052 BindingDB Entry DOI: 10.7270/Q29K4BFR
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%