Affinity Data by PubMed id=20889239

PubMed code 20889239

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332795 (3-(4-methylphenyl)-5-oxo-4,5-dihydro-1,2,4-thiadia...) Show SMILES Cc1ccc(cc1)-c1nc(=O)s[nH]1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
Universidad de la Rep£blica Curated by ChEMBL					More data for this Ligand-Target Pair
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332796 (5-phenyl-1,3,4-oxathiazol-2-one \| CHEMBL1632533) Show SMILES O=c1oc(ns1)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
Universidad de la Rep£blica Curated by ChEMBL					More data for this Ligand-Target Pair
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332793 (2,6-Dibenzyl-4-(5-nitro-furan-2-ylm ethylene)-1,1-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
Universidad de la Rep£blica Curated by ChEMBL					More data for this Ligand-Target Pair
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332792 (4-(5-Nitro-furan-2-ylmethylene)-1,1-dioxo-1,4-dihy...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
Universidad de la Rep£blica Curated by ChEMBL					More data for this Ligand-Target Pair
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332794 (2,3-dichloro-7-hydroxyphenazine5,10-dioxide \| 7,8-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
Universidad de la Rep£blica Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%