Found 74 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402510
(CHEMBL2204087)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O6S/c1-36-23-11-7-20(8-12-23)15-17-30(18-16-25(31)29-33)37(34,35)24-13-9-22(10-14-24)28-26(32)27-19-21-5-3-2-4-6-21/h2-14,33H,15-19H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402514
(CHEMBL2204088)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H32N4O6S/c1-37-24-11-7-22(8-12-24)16-19-31(20-17-26(32)30-34)38(35,36)25-13-9-23(10-14-25)29-27(33)28-18-15-21-5-3-2-4-6-21/h2-14,34H,15-20H2,1H3,(H,30,32)(H2,28,29,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402519
(CHEMBL2204817)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2)cc1 Show InChI InChI=1S/C26H27F3N4O6S/c1-39-22-10-2-18(3-11-22)14-16-33(17-15-24(34)32-36)40(37,38)23-12-8-21(9-13-23)31-25(35)30-20-6-4-19(5-7-20)26(27,28)29/h2-13,36H,14-17H2,1H3,(H,32,34)(H2,30,31,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM13104
(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClN2O5S/c1-24-14-6-8-15(9-7-14)25(22,23)19(11-16(20)18-21)10-12-2-4-13(17)5-3-12/h2-9,21H,10-11H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402513
(CHEMBL2204089)Show SMILES CNC(=O)Nc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccc(OC)cc1 Show InChI InChI=1S/C20H26N4O6S/c1-21-20(26)22-16-5-9-18(10-6-16)31(28,29)24(14-12-19(25)23-27)13-11-15-3-7-17(30-2)8-4-15/h3-10,27H,11-14H2,1-2H3,(H,23,25)(H2,21,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402516
(CHEMBL2204085)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)Nc3ccc(cc3)-c3ccccc3)cc2)cc1 Show InChI InChI=1S/C31H32N4O6S/c1-41-28-15-7-23(8-16-28)19-21-35(22-20-30(36)34-38)42(39,40)29-17-13-27(14-18-29)33-31(37)32-26-11-9-25(10-12-26)24-5-3-2-4-6-24/h2-18,38H,19-22H2,1H3,(H,34,36)(H2,32,33,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402511
(CHEMBL2204802)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-16-6-2-14(3-7-16)10-12-23(13-11-18(24)21-25)30(27,28)17-8-4-15(5-9-17)19(20)22-26/h2-9,25-26H,10-13H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402521
(CHEMBL2204815)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)Nc3ccccc3)cc2)cc1 Show InChI InChI=1S/C25H28N4O6S/c1-35-22-11-7-19(8-12-22)15-17-29(18-16-24(30)28-32)36(33,34)23-13-9-21(10-14-23)27-25(31)26-20-5-3-2-4-6-20/h2-14,32H,15-18H2,1H3,(H,28,30)(H2,26,27,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM13104
(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClN2O5S/c1-24-14-6-8-15(9-7-14)25(22,23)19(11-16(20)18-21)10-12-2-4-13(17)5-3-12/h2-9,21H,10-11H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402512
(CHEMBL2204807)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H24N2O7S2/c1-28-16-5-3-15(4-6-16)11-13-21(14-12-19(22)20-23)30(26,27)18-9-7-17(8-10-18)29(2,24)25/h3-10,23H,11-14H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402515
(CHEMBL2204086)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2)cc1 Show InChI InChI=1S/C25H27ClN4O6S/c1-36-22-10-2-18(3-11-22)14-16-30(17-15-24(31)29-33)37(34,35)23-12-8-21(9-13-23)28-25(32)27-20-6-4-19(26)5-7-20/h2-13,33H,14-17H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402520
(CHEMBL2204816)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O7S/c1-36-22-9-3-19(4-10-22)15-17-30(18-16-25(31)29-33)38(34,35)24-13-7-21(8-14-24)28-26(32)27-20-5-11-23(37-2)12-6-20/h3-14,33H,15-18H2,1-2H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402518
(CHEMBL2204083)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)N(Cc3ccccc3)Cc3ccccc3)cc2)cc1 Show InChI InChI=1S/C33H36N4O6S/c1-43-30-16-12-26(13-17-30)20-22-37(23-21-32(38)35-40)44(41,42)31-18-14-29(15-19-31)34-33(39)36(24-27-8-4-2-5-9-27)25-28-10-6-3-7-11-28/h2-19,40H,20-25H2,1H3,(H,34,39)(H,35,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402532
(CHEMBL2204803)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2cccc(c2)C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-16-7-5-14(6-8-16)9-11-23(12-10-18(24)21-25)30(27,28)17-4-2-3-15(13-17)19(20)22-26/h2-8,13,25-26H,9-12H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402530
(CHEMBL2204805)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C25H27N3O6S/c1-34-22-11-7-19(8-12-22)15-17-28(18-16-24(29)27-31)35(32,33)23-13-9-21(10-14-23)26-25(30)20-5-3-2-4-6-20/h2-14,31H,15-18H2,1H3,(H,26,30)(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402529
(CHEMBL2204806)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C24H27N3O7S2/c1-34-21-11-7-19(8-12-21)15-17-27(18-16-24(28)25-29)36(32,33)23-13-9-20(10-14-23)26-35(30,31)22-5-3-2-4-6-22/h2-14,26,29H,15-18H2,1H3,(H,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402517
(CHEMBL2204084)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)N(c3ccccc3)c3ccccc3)cc2)cc1 Show InChI InChI=1S/C31H32N4O6S/c1-41-28-16-12-24(13-17-28)20-22-34(23-21-30(36)33-38)42(39,40)29-18-14-25(15-19-29)32-31(37)35(26-8-4-2-5-9-26)27-10-6-3-7-11-27/h2-19,38H,20-23H2,1H3,(H,32,37)(H,33,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402557
(CHEMBL2204820)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccccc1 Show InChI InChI=1S/C18H22N2O5S/c1-25-16-7-9-17(10-8-16)26(23,24)20(14-12-18(21)19-22)13-11-15-5-3-2-4-6-15/h2-10,22H,11-14H2,1H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402545
(CHEMBL2204833)Show InChI InChI=1S/C17H26N2O5S/c1-24-15-7-9-16(10-8-15)25(22,23)19(12-11-17(20)18-21)13-14-5-3-2-4-6-14/h7-10,14,21H,2-6,11-13H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402542
(CHEMBL2204836)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C19H24N2O6S/c1-26-16-5-3-15(4-6-16)11-13-21(14-12-19(22)20-23)28(24,25)18-9-7-17(27-2)8-10-18/h3-10,23H,11-14H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402510
(CHEMBL2204087)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O6S/c1-36-23-11-7-20(8-12-23)15-17-30(18-16-25(31)29-33)37(34,35)24-13-9-22(10-14-24)28-26(32)27-19-21-5-3-2-4-6-21/h2-14,33H,15-19H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP in HFF cells assessed as inhibition of collagen deposition after 48 hrs by ELISA |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402533
(CHEMBL2204800)Show SMILES ONC(=O)CCN(CCc1ccccc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C18H20N2O6S/c21-17(19-24)11-13-20(12-10-14-4-2-1-3-5-14)27(25,26)16-8-6-15(7-9-16)18(22)23/h1-9,24H,10-13H2,(H,19,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402546
(CHEMBL2204832)Show InChI InChI=1S/C14H22N2O5S/c1-4-11(2)16(10-9-14(17)15-18)22(19,20)13-7-5-12(21-3)6-8-13/h5-8,11,18H,4,9-10H2,1-3H3,(H,15,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402543
(CHEMBL2204835)Show SMILES COc1ccc(cc1)N(CCC(=O)NO)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-24-14-5-3-13(4-6-14)19(12-11-17(20)18-21)26(22,23)16-9-7-15(25-2)8-10-16/h3-10,21H,11-12H2,1-2H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402534
(CHEMBL2204799)Show InChI InChI=1S/C17H20N2O4S/c20-17(18-21)12-14-19(13-11-15-7-3-1-4-8-15)24(22,23)16-9-5-2-6-10-16/h1-10,21H,11-14H2,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402541
(CHEMBL2204837)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1cccc(OC)c1 Show InChI InChI=1S/C19H24N2O6S/c1-26-16-6-8-18(9-7-16)28(24,25)21(13-11-19(22)20-23)12-10-15-4-3-5-17(14-15)27-2/h3-9,14,23H,10-13H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402504
(CHEMBL2204846)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@@H](CC(O)=O)C(=O)NO |r| Show InChI InChI=1S/C18H20N2O7S/c1-27-14-7-9-15(10-8-14)28(25,26)20(12-13-5-3-2-4-6-13)16(11-17(21)22)18(23)19-24/h2-10,16,24H,11-12H2,1H3,(H,19,23)(H,21,22)/t16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402559
(CHEMBL2204818)Show InChI InChI=1S/C16H18N2O5S/c1-23-14-7-9-15(10-8-14)24(21,22)18(12-11-16(19)17-20)13-5-3-2-4-6-13/h2-10,20H,11-12H2,1H3,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402558
(CHEMBL2204819)Show InChI InChI=1S/C17H20N2O5S/c1-24-15-7-9-16(10-8-15)25(22,23)19(12-11-17(20)18-21)13-14-5-3-2-4-6-14/h2-10,21H,11-13H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402526
(CHEMBL2204810)Show SMILES COc1ccc(CCN(CC(=O)CS)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H23NO6S3/c1-26-17-5-3-15(4-6-17)11-12-20(13-16(21)14-27)29(24,25)19-9-7-18(8-10-19)28(2,22)23/h3-10,27H,11-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402554
(CHEMBL2204823)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCCC(=O)NO)CCc1ccccc1 Show InChI InChI=1S/C19H24N2O5S/c1-26-17-9-11-18(12-10-17)27(24,25)21(14-5-8-19(22)20-23)15-13-16-6-3-2-4-7-16/h2-4,6-7,9-12,23H,5,8,13-15H2,1H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50402512
(CHEMBL2204807)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H24N2O7S2/c1-28-16-5-3-15(4-6-16)11-13-21(14-12-19(22)20-23)30(26,27)18-9-7-17(8-10-18)29(2,24)25/h3-10,23H,11-14H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50402512
(CHEMBL2204807)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H24N2O7S2/c1-28-16-5-3-15(4-6-16)11-13-21(14-12-19(22)20-23)30(26,27)18-9-7-17(8-10-18)29(2,24)25/h3-10,23H,11-14H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402536
(CHEMBL2204091)Show InChI InChI=1S/C16H26N2O5S/c1-3-4-13-24(21,22)18(12-10-16(19)17-20)11-9-14-5-7-15(23-2)8-6-14/h5-8,20H,3-4,9-13H2,1-2H3,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402531
(CHEMBL2204804)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccccc2C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-15-8-6-14(7-9-15)10-12-23(13-11-18(24)21-25)30(27,28)17-5-3-2-4-16(17)19(20)22-26/h2-9,25-26H,10-13H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402544
(CHEMBL2204834)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccccn1 Show InChI InChI=1S/C17H21N3O5S/c1-25-15-5-7-16(8-6-15)26(23,24)20(13-10-17(21)19-22)12-9-14-4-2-3-11-18-14/h2-8,11,22H,9-10,12-13H2,1H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402528
(CHEMBL2204808)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccccc2S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H24N2O7S2/c1-28-16-9-7-15(8-10-16)11-13-21(14-12-19(22)20-23)30(26,27)18-6-4-3-5-17(18)29(2,24)25/h3-10,23H,11-14H2,1-2H3,(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402522
(CHEMBL2204814)Show SMILES COc1ccc(CCN(CCS)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C18H23NO5S3/c1-24-16-5-3-15(4-6-16)11-12-19(13-14-25)27(22,23)18-9-7-17(8-10-18)26(2,20)21/h3-10,25H,11-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402505
(CHEMBL2204845)Show SMILES COc1ccc(cc1)S(=O)(=O)N[C@@H](CC(O)=O)C(=O)NO |r| Show InChI InChI=1S/C11H14N2O7S/c1-20-7-2-4-8(5-3-7)21(18,19)13-9(6-10(14)15)11(16)12-17/h2-5,9,13,17H,6H2,1H3,(H,12,16)(H,14,15)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402555
(CHEMBL2204822)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCCC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C18H22N2O5S/c1-25-16-9-11-17(12-10-16)26(23,24)20(13-5-8-18(21)19-22)14-15-6-3-2-4-7-15/h2-4,6-7,9-12,22H,5,8,13-14H2,1H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402540
(CHEMBL2204839)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H21N3O7S/c1-28-16-6-8-17(9-7-16)29(26,27)20(13-11-18(22)19-23)12-10-14-2-4-15(5-3-14)21(24)25/h2-9,23H,10-13H2,1H3,(H,19,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402525
(CHEMBL2204811)Show SMILES COc1ccc(CCN(CCC(=O)CS)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H25NO6S3/c1-27-18-5-3-16(4-6-18)11-13-21(14-12-17(22)15-28)30(25,26)20-9-7-19(8-10-20)29(2,23)24/h3-10,28H,11-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402523
(CHEMBL2204813)Show SMILES COc1ccc(CCN(CCCS)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H25NO5S3/c1-25-17-6-4-16(5-7-17)12-14-20(13-3-15-26)28(23,24)19-10-8-18(9-11-19)27(2,21)22/h4-11,26H,3,12-15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM11331
(2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxya...)Show InChI InChI=1S/C16H18N2O5S/c1-23-14-7-9-15(10-8-14)24(21,22)18(12-16(19)17-20)11-13-5-3-2-4-6-13/h2-10,20H,11-12H2,1H3,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402527
(CHEMBL2204809)Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccccc1 Show InChI InChI=1S/C21H28N2O4S/c1-21(2,3)18-9-11-19(12-10-18)28(26,27)23(16-14-20(24)22-25)15-13-17-7-5-4-6-8-17/h4-12,25H,13-16H2,1-3H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM13095
(CGS 27023A Analog 23 | N-hydroxy-2-[(4-methoxybenz...)Show InChI InChI=1S/C17H20N2O5S/c1-24-15-7-9-16(10-8-15)25(22,23)19(13-17(20)18-21)12-11-14-5-3-2-4-6-14/h2-10,21H,11-13H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402550
(CHEMBL2204828)Show SMILES COc1ccc(CCN(CC(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C18H22N2O6S/c1-25-15-5-3-14(4-6-15)11-12-20(13-18(21)19-22)27(23,24)17-9-7-16(26-2)8-10-17/h3-10,22H,11-13H2,1-2H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM13104
(2-{[(4-chlorophenyl)methyl](4-methoxybenzene)sulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClN2O5S/c1-24-14-6-8-15(9-7-14)25(22,23)19(11-16(20)18-21)10-12-2-4-13(17)5-3-12/h2-9,21H,10-11H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402539
(CHEMBL2204840)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H23N3O7S2/c1-28-15-4-8-17(9-5-15)30(26,27)21(13-11-18(22)20-23)12-10-14-2-6-16(7-3-14)29(19,24)25/h2-9,23H,10-13H2,1H3,(H,20,22)(H2,19,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50402511
(CHEMBL2204802)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-16-6-2-14(3-7-16)10-12-23(13-11-18(24)21-25)30(27,28)17-8-4-15(5-9-17)19(20)22-26/h2-9,25-26H,10-13H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50402511
(CHEMBL2204802)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-16-6-2-14(3-7-16)10-12-23(13-11-18(24)21-25)30(27,28)17-8-4-15(5-9-17)19(20)22-26/h2-9,25-26H,10-13H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP1 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50402510
(CHEMBL2204087)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O6S/c1-36-23-11-7-20(8-12-23)15-17-30(18-16-25(31)29-33)37(34,35)24-13-9-22(10-14-24)28-26(32)27-19-21-5-3-2-4-6-21/h2-14,33H,15-19H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50402511
(CHEMBL2204802)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(cc2)C(=N)NO)cc1 Show InChI InChI=1S/C19H24N4O6S/c1-29-16-6-2-14(3-7-16)10-12-23(13-11-18(24)21-25)30(27,28)17-8-4-15(5-9-17)19(20)22-26/h2-9,25-26H,10-13H2,1H3,(H2,20,22)(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP2 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50402510
(CHEMBL2204087)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O6S/c1-36-23-11-7-20(8-12-23)15-17-30(18-16-25(31)29-33)37(34,35)24-13-9-22(10-14-24)28-26(32)27-19-21-5-3-2-4-6-21/h2-14,33H,15-19H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP9 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50402510
(CHEMBL2204087)Show SMILES COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C26H30N4O6S/c1-36-23-11-7-20(8-12-23)15-17-30(18-16-25(31)29-33)37(34,35)24-13-9-22(10-14-24)28-26(32)27-19-21-5-3-2-4-6-21/h2-14,33H,15-19H2,1H3,(H,29,31)(H2,27,28,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of para-amino phenylmercuric acetate-activated MMP1 using Mca-P-L-G-L-Dap(Dnp)-A-R-NH2 as substrate after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402556
(CHEMBL2204821)Show InChI InChI=1S/C17H20N2O5S/c1-24-15-9-11-16(12-10-15)25(22,23)19(13-5-8-17(20)18-21)14-6-3-2-4-7-14/h2-4,6-7,9-12,21H,5,8,13H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM13105
(CGS 27023A Analog 33 | N-hydroxy-2-[(4-methoxybenz...)Show SMILES COc1ccc(CN(CC(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C17H20N2O6S/c1-24-14-5-3-13(4-6-14)11-19(12-17(20)18-21)26(22,23)16-9-7-15(25-2)8-10-16/h3-10,21H,11-12H2,1-2H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402553
(CHEMBL2204825)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(F)cc1 Show InChI InChI=1S/C16H17FN2O5S/c1-24-14-6-8-15(9-7-14)25(22,23)19(11-16(20)18-21)10-12-2-4-13(17)5-3-12/h2-9,21H,10-11H2,1H3,(H,18,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402509
(CHEMBL2204841)Show SMILES CNC(=O)[C@H](CCC(O)=O)NC(=O)C(CC(O)=O)CC(=O)NO |r| Show InChI InChI=1S/C12H19N3O8/c1-13-12(22)7(2-3-9(17)18)14-11(21)6(5-10(19)20)4-8(16)15-23/h6-7,23H,2-5H2,1H3,(H,13,22)(H,14,21)(H,15,16)(H,17,18)(H,19,20)/t6?,7-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402506
(CHEMBL2204844)Show SMILES CC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NO |r| Show InChI InChI=1S/C27H33N5O8/c1-16(33)32-12-2-3-23(32)27(39)30-22(14-18-6-10-20(35)11-7-18)26(38)29-21(25(37)28-15-24(36)31-40)13-17-4-8-19(34)9-5-17/h4-11,21-23,34-35,40H,2-3,12-15H2,1H3,(H,28,37)(H,29,38)(H,30,39)(H,31,36)/t21-,22-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402538
(CHEMBL2203295)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCC(=O)NO)CCc1ccc(OC)c(OC)c1 Show InChI InChI=1S/C20H26N2O7S/c1-27-16-5-7-17(8-6-16)30(25,26)22(13-11-20(23)21-24)12-10-15-4-9-18(28-2)19(14-15)29-3/h4-9,14,24H,10-13H2,1-3H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402535
(CHEMBL2204092)Show InChI InChI=1S/C15H24N2O5S/c1-3-4-11-23(20,21)17(12-15(18)16-19)10-9-13-5-7-14(22-2)8-6-13/h5-8,19H,3-4,9-12H2,1-2H3,(H,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402549
(CHEMBL2204829)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O5S/c1-27-14-6-8-15(9-7-14)28(25,26)22(11-16(23)21-24)10-12-2-4-13(5-3-12)17(18,19)20/h2-9,24H,10-11H2,1H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402560
(CHEMBL2204847)Show InChI InChI=1S/C15H16N2O5S/c1-22-13-7-9-14(10-8-13)23(20,21)17(11-15(18)16-19)12-5-3-2-4-6-12/h2-10,19H,11H2,1H3,(H,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402551
(CHEMBL2204827)Show SMILES COc1ccc(cc1)N(CC(=O)NO)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C16H18N2O6S/c1-23-13-5-3-12(4-6-13)18(11-16(19)17-20)25(21,22)15-9-7-14(24-2)8-10-15/h3-10,20H,11H2,1-2H3,(H,17,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402547
(CHEMBL2204831)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCN1CCOCC1)CCC(=O)NO Show InChI InChI=1S/C16H25N3O6S/c1-24-14-2-4-15(5-3-14)26(22,23)19(7-6-16(20)17-21)9-8-18-10-12-25-13-11-18/h2-5,21H,6-13H2,1H3,(H,17,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402507
(CHEMBL2204843)Show SMILES CNC(=O)[C@H](CCC(O)=O)NC(=O)C(CS)CC(O)=O |r| Show InChI InChI=1S/C11H18N2O6S/c1-12-11(19)7(2-3-8(14)15)13-10(18)6(5-20)4-9(16)17/h6-7,20H,2-5H2,1H3,(H,12,19)(H,13,18)(H,14,15)(H,16,17)/t6?,7-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402524
(CHEMBL2204812)Show SMILES COc1ccc(CCN(CCN(O)C(N)=O)S(=O)(=O)c2ccc(cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H25N3O7S2/c1-29-16-5-3-15(4-6-16)11-12-21(13-14-22(24)19(20)23)31(27,28)18-9-7-17(8-10-18)30(2,25)26/h3-10,24H,11-14H2,1-2H3,(H2,20,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402548
(CHEMBL2204830)Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H22N2O5S/c1-29-19-12-14-20(15-13-19)30(27,28)24(16-21(25)23-26)22(17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15,22,26H,16H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM13102
(2-[butan-2-yl(4-methoxybenzene)sulfonamido]-N-hydr...)Show InChI InChI=1S/C13H20N2O5S/c1-4-10(2)15(9-13(16)14-17)21(18,19)12-7-5-11(20-3)6-8-12/h5-8,10,17H,4,9H2,1-3H3,(H,14,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402537
(CHEMBL2204090)Show InChI InChI=1S/C10H14N2O5S/c1-17-8-2-4-9(5-3-8)18(15,16)11-7-6-10(13)12-14/h2-5,11,14H,6-7H2,1H3,(H,12,13) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402552
(CHEMBL2204826)Show SMILES CCCCOC(=O)CN(CC(=O)NO)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C15H22N2O7S/c1-3-4-9-24-15(19)11-17(10-14(18)16-20)25(21,22)13-7-5-12(23-2)6-8-13/h5-8,20H,3-4,9-11H2,1-2H3,(H,16,18) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.67E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50246600
(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)Show InChI InChI=1S/C11H14N2O7S/c1-20-8-2-4-9(5-3-8)21(18,19)13(7-11(15)16)6-10(14)12-17/h2-5,17H,6-7H2,1H3,(H,12,14)(H,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
Bone morphogenetic protein 1
(Homo sapiens (Human)) | BDBM50402508
(CHEMBL2204842)Show SMILES CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NCC(O)=O |r| Show InChI InChI=1S/C12H19N3O8/c1-13-11(22)6(2-3-8(16)17)15-12(23)7(4-9(18)19)14-5-10(20)21/h6-7,14H,2-5H2,1H3,(H,13,22)(H,15,23)(H,16,17)(H,18,19)(H,20,21)/t6-,7-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
FibroGen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of PCP after 1 hr by fluorescence assay |
Bioorg Med Chem Lett 22: 7397-401 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.067
BindingDB Entry DOI: 10.7270/Q22808SM |
More data for this
Ligand-Target Pair | |
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