Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138045
(CHEMBL3753268)Show SMILES CC#CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138047
(CHEMBL3753853)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H28N2O5S2/c1-4-5-8-19(2,3)15(22)7-6-13-11-26-18(25)21(13)9-10-27-17-20-14(12-28-17)16(23)24/h6-7,12-13,15,22H,4-5,8-11H2,1-3H3,(H,23,24)/b7-6+/t13-,15+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138046
(CHEMBL3752435)Show SMILES CC(C)(C)CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C22H32N2O5S2/c1-21(2,3)9-10-22(7-4-8-22)17(25)6-5-15-13-29-20(28)24(15)11-12-30-19-23-16(14-31-19)18(26)27/h5-6,14-15,17,25H,4,7-13H2,1-3H3,(H,26,27)/b6-5+/t15-,17+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138051
(CHEMBL3753221)Show SMILES CCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,2-4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138050
(CHEMBL3752406)Show SMILES CC(C)(CCCCF)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H27FN2O5S2/c1-19(2,7-3-4-8-20)15(23)6-5-13-11-27-18(26)22(13)9-10-28-17-21-14(12-29-17)16(24)25/h5-6,12-13,15,23H,3-4,7-11H2,1-2H3,(H,24,25)/b6-5+/t13-,15+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 431 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138055
(CHEMBL3753622)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCc2ccccc2)CCC1 |r| Show InChI InChI=1S/C24H28N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h1-3,5-8,16,18,20,27H,4,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 802 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138052
(CHEMBL3751951)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCCCF)CCC1 |r| Show InChI InChI=1S/C20H27FN2O5S2/c21-9-2-1-6-20(7-3-8-20)16(24)5-4-14-12-28-19(27)23(14)10-11-29-18-22-15(13-30-18)17(25)26/h4-5,13-14,16,24H,1-3,6-12H2,(H,25,26)/b5-4+/t14-,16+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138044
(CHEMBL3754197)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCC2CCCCC2)CCC1 |r| Show InChI InChI=1S/C24H34N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h7-8,16-18,20,27H,1-6,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138054
(CHEMBL3753898)Show SMILES CCOCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-2-27-10-8-20(6-3-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50138053
(CHEMBL3753788)Show SMILES COCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-27-10-3-8-20(6-2-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138051
(CHEMBL3753221)Show SMILES CCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,2-4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138101
(CHEMBL3754586)Show SMILES CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-3-4-5-14(2)12-16(23)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h6,8,13-16,23H,3-5,7,9-12H2,1-2H3,(H,25,26)/b8-6+/t14-,15-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138050
(CHEMBL3752406)Show SMILES CC(C)(CCCCF)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H27FN2O5S2/c1-19(2,7-3-4-8-20)15(23)6-5-13-11-27-18(26)22(13)9-10-28-17-21-14(12-29-17)16(24)25/h5-6,12-13,15,23H,3-4,7-11H2,1-2H3,(H,24,25)/b6-5+/t13-,15+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138044
(CHEMBL3754197)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCC2CCCCC2)CCC1 |r| Show InChI InChI=1S/C24H34N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h7-8,16-18,20,27H,1-6,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.39E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138044
(CHEMBL3754197)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCC2CCCCC2)CCC1 |r| Show InChI InChI=1S/C24H34N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h7-8,16-18,20,27H,1-6,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138052
(CHEMBL3751951)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCCCF)CCC1 |r| Show InChI InChI=1S/C20H27FN2O5S2/c21-9-2-1-6-20(7-3-8-20)16(24)5-4-14-12-28-19(27)23(14)10-11-29-18-22-15(13-30-18)17(25)26/h4-5,13-14,16,24H,1-3,6-12H2,(H,25,26)/b5-4+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138054
(CHEMBL3753898)Show SMILES CCOCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-2-27-10-8-20(6-3-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 745 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138046
(CHEMBL3752435)Show SMILES CC(C)(C)CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C22H32N2O5S2/c1-21(2,3)9-10-22(7-4-8-22)17(25)6-5-15-13-29-20(28)24(15)11-12-30-19-23-16(14-31-19)18(26)27/h5-6,14-15,17,25H,4,7-13H2,1-3H3,(H,26,27)/b6-5+/t15-,17+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.71E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138047
(CHEMBL3753853)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H28N2O5S2/c1-4-5-8-19(2,3)15(22)7-6-13-11-26-18(25)21(13)9-10-27-17-20-14(12-28-17)16(23)24/h6-7,12-13,15,22H,4-5,8-11H2,1-3H3,(H,23,24)/b7-6+/t13-,15+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138052
(CHEMBL3751951)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCCCF)CCC1 |r| Show InChI InChI=1S/C20H27FN2O5S2/c21-9-2-1-6-20(7-3-8-20)16(24)5-4-14-12-28-19(27)23(14)10-11-29-18-22-15(13-30-18)17(25)26/h4-5,13-14,16,24H,1-3,6-12H2,(H,25,26)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138045
(CHEMBL3753268)Show SMILES CC#CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138102
(CHEMBL3752377)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-4-5-10-20(2,3)16(23)8-6-14-7-9-17(24)22(14)11-12-27-19-21-15(13-28-19)18(25)26/h6,8,13-14,16,23H,4-5,7,9-12H2,1-3H3,(H,25,26)/b8-6+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138055
(CHEMBL3753622)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCc2ccccc2)CCC1 |r| Show InChI InChI=1S/C24H28N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h1-3,5-8,16,18,20,27H,4,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138046
(CHEMBL3752435)Show SMILES CC(C)(C)CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C22H32N2O5S2/c1-21(2,3)9-10-22(7-4-8-22)17(25)6-5-15-13-29-20(28)24(15)11-12-30-19-23-16(14-31-19)18(26)27/h5-6,14-15,17,25H,4,7-13H2,1-3H3,(H,26,27)/b6-5+/t15-,17+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138051
(CHEMBL3753221)Show SMILES CCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,2-4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138055
(CHEMBL3753622)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCc2ccccc2)CCC1 |r| Show InChI InChI=1S/C24H28N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h1-3,5-8,16,18,20,27H,4,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 465 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138101
(CHEMBL3754586)Show SMILES CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-3-4-5-14(2)12-16(23)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h6,8,13-16,23H,3-5,7,9-12H2,1-2H3,(H,25,26)/b8-6+/t14-,15-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138053
(CHEMBL3753788)Show SMILES COCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-27-10-3-8-20(6-2-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138052
(CHEMBL3751951)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCCCF)CCC1 |r| Show InChI InChI=1S/C20H27FN2O5S2/c21-9-2-1-6-20(7-3-8-20)16(24)5-4-14-12-28-19(27)23(14)10-11-29-18-22-15(13-30-18)17(25)26/h4-5,13-14,16,24H,1-3,6-12H2,(H,25,26)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 195 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138045
(CHEMBL3753268)Show SMILES CC#CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138055
(CHEMBL3753622)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCc2ccccc2)CCC1 |r| Show InChI InChI=1S/C24H28N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h1-3,5-8,16,18,20,27H,4,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138050
(CHEMBL3752406)Show SMILES CC(C)(CCCCF)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H27FN2O5S2/c1-19(2,7-3-4-8-20)15(23)6-5-13-11-27-18(26)22(13)9-10-28-17-21-14(12-29-17)16(24)25/h5-6,12-13,15,23H,3-4,7-11H2,1-2H3,(H,24,25)/b6-5+/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138050
(CHEMBL3752406)Show SMILES CC(C)(CCCCF)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H27FN2O5S2/c1-19(2,7-3-4-8-20)15(23)6-5-13-11-27-18(26)22(13)9-10-28-17-21-14(12-29-17)16(24)25/h5-6,12-13,15,23H,3-4,7-11H2,1-2H3,(H,24,25)/b6-5+/t13-,15+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138051
(CHEMBL3753221)Show SMILES CCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,2-4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138047
(CHEMBL3753853)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H28N2O5S2/c1-4-5-8-19(2,3)15(22)7-6-13-11-26-18(25)21(13)9-10-27-17-20-14(12-28-17)16(23)24/h6-7,12-13,15,22H,4-5,8-11H2,1-3H3,(H,23,24)/b7-6+/t13-,15+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138047
(CHEMBL3753853)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C19H28N2O5S2/c1-4-5-8-19(2,3)15(22)7-6-13-11-26-18(25)21(13)9-10-27-17-20-14(12-28-17)16(23)24/h6-7,12-13,15,22H,4-5,8-11H2,1-3H3,(H,23,24)/b7-6+/t13-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138102
(CHEMBL3752377)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-4-5-10-20(2,3)16(23)8-6-14-7-9-17(24)22(14)11-12-27-19-21-15(13-28-19)18(25)26/h6,8,13-14,16,23H,4-5,7,9-12H2,1-3H3,(H,25,26)/b8-6+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138054
(CHEMBL3753898)Show SMILES CCOCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-2-27-10-8-20(6-3-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138053
(CHEMBL3753788)Show SMILES COCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-27-10-3-8-20(6-2-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138102
(CHEMBL3752377)Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-4-5-10-20(2,3)16(23)8-6-14-7-9-17(24)22(14)11-12-27-19-21-15(13-28-19)18(25)26/h6,8,13-14,16,23H,4-5,7,9-12H2,1-3H3,(H,25,26)/b8-6+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138044
(CHEMBL3754197)Show SMILES O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCC2CCCCC2)CCC1 |r| Show InChI InChI=1S/C24H34N2O5S2/c27-20(24(10-4-11-24)12-9-17-5-2-1-3-6-17)8-7-18-15-31-23(30)26(18)13-14-32-22-25-19(16-33-22)21(28)29/h7-8,16-18,20,27H,1-6,9-15H2,(H,28,29)/b8-7+/t18-,20+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50138054
(CHEMBL3753898)Show SMILES CCOCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-2-27-10-8-20(6-3-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP3 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138046
(CHEMBL3752435)Show SMILES CC(C)(C)CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C22H32N2O5S2/c1-21(2,3)9-10-22(7-4-8-22)17(25)6-5-15-13-29-20(28)24(15)11-12-30-19-23-16(14-31-19)18(26)27/h5-6,14-15,17,25H,4,7-13H2,1-3H3,(H,26,27)/b6-5+/t15-,17+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138045
(CHEMBL3753268)Show SMILES CC#CCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O5S2/c1-2-3-7-20(8-4-9-20)16(23)6-5-14-12-27-19(26)22(14)10-11-28-18-21-15(13-29-18)17(24)25/h5-6,13-14,16,23H,4,7-12H2,1H3,(H,24,25)/b6-5+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50138053
(CHEMBL3753788)Show SMILES COCCCC1(CCC1)[C@H](O)\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H28N2O6S2/c1-27-10-3-8-20(6-2-7-20)16(23)5-4-14-12-28-19(26)22(14)9-11-29-18-21-15(13-30-18)17(24)25/h4-5,13-14,16,23H,2-3,6-12H2,1H3,(H,24,25)/b5-4+/t14-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 705 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP4 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50138101
(CHEMBL3754586)Show SMILES CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| Show InChI InChI=1S/C20H30N2O4S2/c1-3-4-5-14(2)12-16(23)8-6-15-7-9-18(24)22(15)10-11-27-20-21-17(13-28-20)19(25)26/h6,8,13-16,23H,3-5,7,9-12H2,1-2H3,(H,25,26)/b8-6+/t14-,15-,16+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.390 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Agonist activity at human EP2 receptor |
Bioorg Med Chem Lett 26: 1016-9 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.039
BindingDB Entry DOI: 10.7270/Q2JS9S81 |
More data for this
Ligand-Target Pair | |
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