Found 18 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203146
(CHEMBL3902533)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@@H](O)Cc(n3)c12)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C20H22ClN5O3/c1-2-26-19-13(9-22-26)7-18-23-16(19)8-15(27)10-29-11-17(24-20(28)25-18)12-4-3-5-14(21)6-12/h3-7,9,15,17,27H,2,8,10-11H2,1H3,(H2,23,24,25,28)/t15-,17+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.996 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203125
(CHEMBL3917936)Show SMILES CCn1ncc2cc3NC(=O)N[C@H]([C@@H](CO)OCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C21H25N5O3/c1-2-26-20-15(12-22-26)11-18-23-16(20)9-6-10-29-17(13-27)19(25-21(28)24-18)14-7-4-3-5-8-14/h3-5,7-8,11-12,17,19,27H,2,6,9-10,13H2,1H3,(H2,23,24,25,28)/t17-,19+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203124
(CHEMBL3916619)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@H](O)Cc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-25-19-14(10-21-25)8-18-22-16(19)9-15(26)11-28-12-17(23-20(27)24-18)13-6-4-3-5-7-13/h3-8,10,15,17,26H,2,9,11-12H2,1H3,(H2,22,23,24,27)/t15-,17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203118
(CHEMBL3962242)Show SMILES [H][C@]1(OCCCc2nc(NC(=O)N[C@@H]1c1ccccc1)cc1cnn(CC)c21)[C@H](C)O |r| Show InChI InChI=1S/C22H27N5O3/c1-3-27-20-16(13-23-27)12-18-24-17(20)10-7-11-30-21(14(2)28)19(26-22(29)25-18)15-8-5-4-6-9-15/h4-6,8-9,12-14,19,21,28H,3,7,10-11H2,1-2H3,(H2,24,25,26,29)/t14-,19+,21-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203114
(CHEMBL3936937)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COCCNc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C19H22N6O2/c1-2-25-17-14(11-21-25)10-16-23-18(17)20-8-9-27-12-15(22-19(26)24-16)13-6-4-3-5-7-13/h3-7,10-11,15H,2,8-9,12H2,1H3,(H3,20,22,23,24,26)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203116
(CHEMBL3925782)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@@H](O)Cc(n3)c12)c1ccc(Cl)c(F)c1 |r| Show InChI InChI=1S/C20H21ClFN5O3/c1-2-27-19-12(8-23-27)6-18-24-16(19)7-13(28)9-30-10-17(25-20(29)26-18)11-3-4-14(21)15(22)5-11/h3-6,8,13,17,28H,2,7,9-10H2,1H3,(H2,24,25,26,29)/t13-,17+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203117
(CHEMBL3934673)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@@H](O)Cc(n3)c12)c1ccc(OC)c(F)c1 |r| Show InChI InChI=1S/C21H24FN5O4/c1-3-27-20-13(9-23-27)7-19-24-16(20)8-14(28)10-31-11-17(25-21(29)26-19)12-4-5-18(30-2)15(22)6-12/h4-7,9,14,17,28H,3,8,10-11H2,1-2H3,(H2,24,25,26,29)/t14-,17+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203152
(CHEMBL3964039)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N5O2/c1-2-25-19-15(12-21-25)11-18-22-16(19)9-6-10-27-13-17(23-20(26)24-18)14-7-4-3-5-8-14/h3-5,7-8,11-12,17H,2,6,9-10,13H2,1H3,(H2,22,23,24,26)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203150
(CHEMBL3980079)Show SMILES Cn1ncc2cc3NC(=O)N[C@H](COCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C19H21N5O2/c1-24-18-14(11-20-24)10-17-21-15(18)8-5-9-26-12-16(22-19(25)23-17)13-6-3-2-4-7-13/h2-4,6-7,10-11,16H,5,8-9,12H2,1H3,(H2,21,22,23,25)/t16-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203115
(CHEMBL3986381)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@@H](O)Cc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-25-19-14(10-21-25)8-18-22-16(19)9-15(26)11-28-12-17(23-20(27)24-18)13-6-4-3-5-7-13/h3-8,10,15,17,26H,2,9,11-12H2,1H3,(H2,22,23,24,27)/t15-,17+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203151
(CHEMBL3962160)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](COC[C@@H](O)Cc(n3)c12)c1cccc(F)c1 |r| Show InChI InChI=1S/C20H22FN5O3/c1-2-26-19-13(9-22-26)7-18-23-16(19)8-15(27)10-29-11-17(24-20(28)25-18)12-4-3-5-14(21)6-12/h3-7,9,15,17,27H,2,8,10-11H2,1H3,(H2,23,24,25,28)/t15-,17+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203149
(CHEMBL3954524)Show SMILES CCn1ncc2cc3NC(=O)N[C@@H](c4ccccc4)C(C)(C)OCCCc(n3)c12 |r| Show InChI InChI=1S/C22H27N5O2/c1-4-27-19-16(14-23-27)13-18-24-17(19)11-8-12-29-22(2,3)20(26-21(28)25-18)15-9-6-5-7-10-15/h5-7,9-10,13-14,20H,4,8,11-12H2,1-3H3,(H2,24,25,26,28)/t20-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203148
(CHEMBL3909003)Show SMILES CCn1ncc2cc3NC(=O)N[C@H]([C@@H](O)OCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-25-18-14(12-21-25)11-16-22-15(18)9-6-10-28-19(26)17(24-20(27)23-16)13-7-4-3-5-8-13/h3-5,7-8,11-12,17,19,26H,2,6,9-10H2,1H3,(H2,22,23,24,27)/t17-,19-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203120
(CHEMBL3927938)Show SMILES CCn1ncc2cc3NC(=O)N[C@H]([C@H](O)OCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N5O3/c1-2-25-18-14(12-21-25)11-16-22-15(18)9-6-10-28-19(26)17(24-20(27)23-16)13-7-4-3-5-8-13/h3-5,7-8,11-12,17,19,26H,2,6,9-10H2,1H3,(H2,22,23,24,27)/t17-,19+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203119
(CHEMBL3899948)Show SMILES CCn1ncc2cc3NC(=O)N[C@@H](c4ccccc4)C(C)(C)OC\C=C/c(n3)c12 |r,c:25| Show InChI InChI=1S/C22H25N5O2/c1-4-27-19-16(14-23-27)13-18-24-17(19)11-8-12-29-22(2,3)20(26-21(28)25-18)15-9-6-5-7-10-15/h5-11,13-14,20H,4,12H2,1-3H3,(H2,24,25,26,28)/b11-8-/t20-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 634 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203147
(CHEMBL3893222)Show SMILES [H][C@]1(OCCCc2nc(NC(=O)N[C@@H]1c1ccccc1)cc1cnn(CC)c21)[C@@H](C)O |r| Show InChI InChI=1S/C22H27N5O3/c1-3-27-20-16(13-23-27)12-18-24-17(20)10-7-11-30-21(14(2)28)19(26-22(29)25-18)15-8-5-4-6-9-15/h4-6,8-9,12-14,19,21,28H,3,7,10-11H2,1-2H3,(H2,24,25,26,29)/t14-,19-,21+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 687 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203123
(CHEMBL3926893)Show SMILES CCn1ncc2cc3NC(=O)N[C@H](c4ccccc4)C(C)(C)OCCCc(n3)c12 |r| Show InChI InChI=1S/C22H27N5O2/c1-4-27-19-16(14-23-27)13-18-24-17(19)11-8-12-29-22(2,3)20(26-21(28)25-18)15-9-6-5-7-10-15/h5-7,9-10,13-14,20H,4,8,11-12H2,1-3H3,(H2,24,25,26,28)/t20-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 734 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50203121
(CHEMBL3945821)Show SMILES CCn1ncc2cc3NC(=O)N[C@@H]([C@H](CO)OCCCc(n3)c12)c1ccccc1 |r| Show InChI InChI=1S/C21H25N5O3/c1-2-26-20-15(12-22-26)11-18-23-16(20)9-6-10-29-17(13-27)19(25-21(28)24-18)14-7-4-3-5-8-14/h3-5,7-8,11-12,17,19,27H,2,6,9-10,13H2,1H3,(H2,23,24,25,28)/t17-,19+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 757 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC
Curated by ChEMBL
| Assay Description
Inhibition of human activated ERK2 assessed as reduction in phosphorylation activity preincubated for 15 mins followed by addition of IMAP peptide as... |
ACS Med Chem Lett 7: 1020-1021 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00434
BindingDB Entry DOI: 10.7270/Q26Q207M |
More data for this
Ligand-Target Pair | |
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