Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (GUINEA PIG) | BDBM22904 ((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity of compound towards Histamine H3 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine radioligand | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069825 (4-Pyrrolidin-3-yl-1H-imidazole | CHEMBL79983) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069816 (4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069823 (4-((3S,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50034708 (4-((2R,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069822 (4-((3S,4S)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069818 (4-((2R,3S)-2-Methyl-azetidin-3-yl)-1H-imidazole | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069819 (4-((2S,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069817 (4-((3S,5S)-5-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 76 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069820 (4-((2R,3S)-2-Ethyl-pyrrolidin-3-yl)-1H-imidazole |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069815 (4-((S)-3-Methyl-pyrrolidin-3-yl)-1H-imidazole | CH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069821 (4-((2R,3S)-2-Benzyl-pyrrolidin-3-yl)-1H-imidazole ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (GUINEA PIG) | BDBM50069824 ((2R,3S)-3-(1H-Imidazol-4-yl)-2-methyl-piperidine |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-N-alpha-methylhistamine binding to guinea pig brain Histamine H3 receptor | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM22904 ((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity of the compound to H-1 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine ligand | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50069816 (4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole ...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity of the compound to H-1 receptor was determined in guinea pig brain tissue using [3H]- N alpha-methylhistamine ligand | Bioorg Med Chem Lett 8: 243-8 (1999) BindingDB Entry DOI: 10.7270/Q2ST7P0Z | |||||||||||
More data for this Ligand-Target Pair |