| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin G |
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| Ligand | BDBM50058975 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_45347 (CHEMBL661885) |
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| IC50 | 780.0±n/a nM |
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| Citation |  Niwata, S; Fukami, H; Sumida, M; Ito, A; Kakutani, S; Saitoh, M; Suzuki, K; Imoto, M; Shibata, H; Imajo, S; Kiso, Y; Tanaka, T; Nakazato, H; Ishihara, T; Takai, S; Yamamoto, D; Shiota, N; Miyazaki, M; Okunishi, H; Kinoshita, A; Urata, H; Arakawa, K Substituted 3-(phenylsulfonyl)-1-phenylimidazolidine-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase. J Med Chem40:2156-63 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin G |
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| Name: | Cathepsin G |
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| Synonyms: | CATG_HUMAN | CG | CTSG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28860.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1469016 |
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| Residue: | 255 |
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| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
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| BDBM50058975 |
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| n/a |
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| Name | BDBM50058975 |
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| Synonyms: | 3-(2,5-Dioxo-3-phenyl-imidazolidine-1-sulfonyl)-benzonitrile | CHEMBL431187 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11N3O4S |
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| Mol. Mass. | 341.341 |
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| SMILES | O=C1CN(C(=O)N1S(=O)(=O)c1cccc(c1)C#N)c1ccccc1 |
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| Structure | 
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