| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase A |
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| Ligand | BDBM50125728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_51874 (CHEMBL666529) |
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| IC50 | 3950±n/a nM |
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| Citation |  Wu, YQ; Belyakov, S; Choi, C; Limburg, D; Thomas IV, BE; Vaal, M; Wei, L; Wilkinson, DE; Holmes, A; Fuller, M; McCormick, J; Connolly, M; Moeller, T; Steiner, J; Hamilton, GS Synthesis and biological evaluation of non-peptidic cyclophilin ligands. J Med Chem46:1112-5 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase A |
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| Name: | Peptidyl-prolyl cis-trans isomerase A |
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| Synonyms: | Cyclophilin A | PPIA_RAT | Ppia |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17878.16 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_51874 |
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| Residue: | 164 |
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| Sequence: | MVNPTVFFDITADGEPLGRVCFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMSIVEAMERFGSRNGKTSKKITISDCGQL
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| BDBM50125728 |
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| n/a |
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| Name | BDBM50125728 |
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| Synonyms: | CHEMBL13550 | N-(3,5-dichlorophenyl)-N'-{3-[({[(3,5-dichlorophenyl)amino]carbonyl}amino)methyl]benzyl}urea |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18Cl4N4O2 |
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| Mol. Mass. | 512.216 |
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| SMILES | Clc1cc(Cl)cc(NC(=O)NCc2cccc(CNC(=O)Nc3cc(Cl)cc(Cl)c3)c2)c1 |
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| Structure | 
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