| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
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| Ligand | BDBM258466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2080917 (CHEMBL4736708) |
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| EC50 | 3.6±n/a nM |
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| Citation |  Gilmore, JL; Xiao, HY; Dhar, TGM; Yang, M; Xiao, Z; Yang, X; Taylor, TL; McIntyre, KW; Warrack, BM; Shi, H; Levesque, PC; Marino, AM; Cornelius, G; Mathur, A; Shen, DR; Pang, J; Cvijic, ME; Lehman-McKeeman, LD; Sun, H; Xie, J; Salter-Cid, L; Carter, PH; Dyckman, AJ Bicyclic Ligand-Biased Agonists of S1P J Med Chem64:1454-1480 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 5 |
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| Name: | Sphingosine 1-phosphate receptor 5 |
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| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41796.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 398 |
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| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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| BDBM258466 |
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| n/a |
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| Name | BDBM258466 |
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| Synonyms: | US9522888, 689 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H36NO5P |
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| Mol. Mass. | 425.4987 |
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| SMILES | COCCCCC[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| |
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| Structure | 
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