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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Peroxisome proliferator-activated receptor gamma | ||
| Ligand | BDBM50362972 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_801272 (CHEMBL1947821) | ||
| EC50 | 4.1±n/a nM | ||
| Citation |  Liu, W; Lau, F; Liu, K; Wood, HB; Zhou, G; Chen, Y; Li, Y; Akiyama, TE; Castriota, G; Einstein, M; Wang, C; McCann, ME; Doebber, TW; Wu, M; Chang, CH; McNamara, L; McKeever, B; Mosley, RT; Berger, JP; Meinke, PT Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor¿ (PPAR¿) modulators. J Med Chem54:8541-54 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Peroxisome proliferator-activated receptor gamma | |||
| Name: | Peroxisome proliferator-activated receptor gamma | ||
| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 | ||
| Type: | Nuclear Receptor | ||
| Mol. Mass.: | 57613.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37231 | ||
| Residue: | 505 | ||
| Sequence: |
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| BDBM50362972 | |||
| n/a | |||
| Name | BDBM50362972 | ||
| Synonyms: | CHEMBL1946571 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H19ClF3N3O5 | ||
| Mol. Mass. | 545.894 | ||
| SMILES | C[C@@H](Oc1cc(Cn2c3cc(ccc3n(-c3noc4c(C)cccc34)c2=O)C(F)(F)F)ccc1Cl)C(O)=O |r,wU:1.0,(3.41,-20.44,;3.38,-18.9,;2.03,-18.16,;.71,-18.95,;-.63,-18.21,;-1.94,-19.01,;-3.29,-18.26,;-3.31,-16.72,;-4.78,-16.25,;-6.12,-17.03,;-7.46,-16.26,;-7.45,-14.72,;-6.12,-13.94,;-4.79,-14.71,;-3.33,-14.22,;-2.56,-12.89,;-3.46,-11.64,;-2.55,-10.4,;-1.09,-10.89,;.25,-10.13,;.25,-8.59,;1.58,-10.9,;1.57,-12.45,;.23,-13.21,;-1.1,-12.43,;-2.41,-15.47,;-.87,-15.46,;-8.79,-17.03,;-10.12,-16.26,;-8.79,-18.57,;-10.13,-17.79,;-1.92,-20.54,;-.58,-21.29,;.74,-20.5,;2.09,-21.25,;4.7,-18.1,;6.05,-18.84,;4.67,-16.56,)| | ||
| Structure | 
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