| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50268943 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1705548 (CHEMBL4056781) |
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| EC50 | 77±n/a nM |
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| Citation |  Jang, YK; Lee, KM; Jung, KY; Kang, SK; Pagire, SH; Lee, JM; Pagire, HS; Kim, KR; Bae, MA; Lee, H; Rhee, SD; Ahn, JH Design, synthesis, and biological evaluation of aryl N-methoxyamide derivatives as GPR119 agonists. Bioorg Med Chem Lett27:3909-3914 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50268943 |
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| n/a |
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| Name | BDBM50268943 |
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| Synonyms: | CHEMBL4089778 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30FN5O3 |
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| Mol. Mass. | 479.5465 |
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| SMILES | CCc1cnc(nc1)N1CCC(COc2ccc(nc2)-c2ccc(C(=O)N(C)OC)c(F)c2)CC1 |
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| Structure | 
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