| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
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| Ligand | BDBM50468143 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1798205 (CHEMBL4270322) |
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| IC50 | 1.2±n/a nM |
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| Citation |  Liu, W; Hussain, Z; Zang, Y; Sweis, RF; Romero, FA; Finke, PE; Moningka, R; Bao, J; Plotkin, MA; Shang, J; Dingley, KH; Salituro, G; Murphy, BA; Howard, AD; Ujjainwalla, F; Wood, HB; Duffy, JL Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists. ACS Med Chem Lett9:1088-1093 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 5 |
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| Name: | Somatostatin receptor type 5 |
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| Synonyms: | SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39218.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35346 |
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| Residue: | 364 |
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| Sequence: | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
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| BDBM50468143 |
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| n/a |
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| Name | BDBM50468143 |
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| Synonyms: | CHEMBL4281446 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25F3N2O4 |
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| Mol. Mass. | 474.4722 |
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| SMILES | OC(=O)c1ccc(cc1)N1CC2(CCN(Cc3ccc(c(c3)C3CC3)C(F)(F)F)CC2)OC1=O |
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| Structure | 
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