| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50101881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212862 |
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| Ki | 610±n/a nM |
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| Citation |  Rai, R; Kolesnikov, A; Li, Y; Young, WB; Leahy, E; Sprengeler, PA; Verner, E; Shrader, WD; Burgess-Henry, J; Sangalang, JC; Allen, D; Chen, X; Katz, BA; Luong, C; Elrod, K; Cregar, L Development of potent and selective factor Xa inhibitors. Bioorg Med Chem Lett11:1797-800 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50101881 |
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| n/a |
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| Name | BDBM50101881 |
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| Synonyms: | 4-[3-(3-Benzyl-5-carbamimidoyl-1H-indol-2-yl)-5-bromo-4-hydroxy-phenyl]-butyric acid | CHEMBL50649 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24BrN3O3 |
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| Mol. Mass. | 506.391 |
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| SMILES | NC(=N)c1ccc2[nH]c(c(Cc3ccccc3)c2c1)-c1cc(CCCC(O)=O)cc(Br)c1O |
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| Structure | 
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