| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50095998 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_103898 (CHEMBL711480) |
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| Kd | 2500000±n/a nM |
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| Citation |  Orita, M; Yamamoto, S; Katayama, N; Aoki, M; Takayama, K; Yamagiwa, Y; Seki, N; Suzuki, H; Kurihara, H; Sakashita, H; Takeuchi, M; Fujita, S; Yamada, T; Tanaka, A Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography. J Med Chem44:540-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50095998 |
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| n/a |
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| Name | BDBM50095998 |
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| Synonyms: | CHEMBL345292 | Hexylglutathione | L-gamma-glutamyl-S-hexyl-L-cysteinylglycine | S-hexylglutathione |
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| Type | Small organic molecule |
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| Emp. Form. | C16H29N3O6S |
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| Mol. Mass. | 391.483 |
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| SMILES | CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O |
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| Structure | 
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