| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight phosphotyrosine protein phosphatase |
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| Ligand | BDBM50420258 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1513412 (CHEMBL3611567) |
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| IC50 | >200000±n/a nM |
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| Citation |  He, R; Yu, ZH; Zhang, RY; Wu, L; Gunawan, AM; Lane, BS; Shim, JS; Zeng, LF; He, Y; Chen, L; Wells, CD; Liu, JO; Zhang, ZY Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. ACS Med Chem Lett6:782-6 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight phosphotyrosine protein phosphatase |
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| Name: | Low molecular weight phosphotyrosine protein phosphatase |
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| Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
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| Type: | n/a |
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| Mol. Mass.: | 18042.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24666 |
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| Residue: | 158 |
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| Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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| BDBM50420258 |
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| n/a |
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| Name | BDBM50420258 |
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| Synonyms: | CEFSULODIN |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N4O8S2 |
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| Mol. Mass. | 533.554 |
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| SMILES | NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)C(c2ccccc2)S(O)(=O)=O)C3=O)C(O)=O)cc1 |t:8| |
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| Structure | 
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