| Reaction Details |
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 | Report a problem with these data |
| Target | Choline kinase alpha |
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| Ligand | BDBM50145931 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1554155 (CHEMBL3769127) |
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| Kd | 769±n/a nM |
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| Citation |  Zech, SG; Kohlmann, A; Zhou, T; Li, F; Squillace, RM; Parillon, LE; Greenfield, MT; Miller, DP; Qi, J; Thomas, RM; Wang, Y; Xu, Y; Miret, JJ; Shakespeare, WC; Zhu, X; Dalgarno, DC Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery. J Med Chem59:671-86 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Choline kinase alpha |
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| Name: | Choline kinase alpha |
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| Synonyms: | CHK | CHKA | CHKA_HUMAN | CKI | Choline kinase alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52248.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290064 |
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| Residue: | 457 |
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| Sequence: | MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
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| BDBM50145931 |
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| n/a |
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| Name | BDBM50145931 |
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| Synonyms: | CHEMBL3764898 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H34N4 |
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| Mol. Mass. | 378.5536 |
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| SMILES | CN1CCN(CC1)c1ccc(cc1)-c1ccc(CN2CCCN(C)CC2)cc1 |
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| Structure | 
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