| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
|---|
| Ligand | BDBM50206018 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1628615 (CHEMBL3871200) |
|---|
| EC50 | >10000±n/a nM |
|---|
| Citation |  Sugimoto, I; Kambe, T; Okino, T; Obitsu, T; Ohta, N; Nishiyama, T; Kinoshita, A; Fujimoto, T; Egashira, H; Yamane, S; Shuto, S; Tani, K; Maruyama, T Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists. ACS Med Chem Lett8:107-112 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP2 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP2 subtype |
|---|
| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39775.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43116 |
|---|
| Residue: | 358 |
|---|
| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
|
|
|
|---|
| BDBM50206018 |
|---|
| n/a |
|---|
| Name | BDBM50206018 |
|---|
| Synonyms: | CHEMBL3967855 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H32O6 |
|---|
| Mol. Mass. | 404.4966 |
|---|
| SMILES | [H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)COc3ccccc3)[C@@]1([H])CC[C@H](CCCC(O)=O)CO2 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
