92 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25922884	5	Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis.	Riken Center For Sustainable Resource Science
25016232	109	CoMFA and CoMSIA analysis of ACE-inhibitory, antimicrobial and bitter-tasting peptides.	Tianjin University
24900839	24	Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes.	Vanderbilt University Department of Chemistry
24735644	19	Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-ß hydrolysis.	University of Lille
23061607	10	Organosilicon molecules with medicinal applications.	University of California Davis
3379417	5	Chemical and pharmaceutical studies on medicinal plants in Paraguay. Geraniin, an angiotensin-converting enzyme inhibitor from "paraparai mi," Phyllanthus niruri.	TBA
18078750	76	Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite.	Glaxosmithkline
9379435	30	Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.	University of Michigan
7629809	140	Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues.	University of Illinois At Chicago
8360884	134	Three-dimensional quantitative structure-activity relationship of angiotesin-converting enzyme and thermolysin inhibitors. II. A comparison of CoMFA models incorporating molecular orbital fields and desolvation free energies based on active-analog and complementary-receptor-field alignment rules.	Washington University
	20	Dual metalloprotease inhibitors. III. utilization of bicyclic and monocyclic diazepinone based mercaptoacetyls	TBA
	26	Dual metalloprotease inhibitors. II. Effect of substitution and stereochemistry on benzazepinone based mercaptoacetyls	TBA
	30	Dual metalloprotease inhibitors. I. constrained peptidomimetics of mercaptoacyl dipeptides	TBA
21413808	170	Synopsis of some recent tactical application of bioisosteres in drug design.	Bristol-Myers Squibb Pharmaceutical Research and Development
21381769	56	Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.	Universite£
22882079	26	Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase.	Aarhus University
21780776	40	Remarkable potential of thea-aminophosphonate/phosphinate structural motif in medicinal chemistry.	Wroclaw University of Technology
19715320	87	Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.	University of Florida
19596577	26	Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.	Dipartimento Di Chimica
18160283	26	Targeting ACE and ECE with dual acting inhibitors.	Universit£
16220969	219	Designed multiple ligands. An emerging drug discovery paradigm.	Organon Laboratories
15658862	30	Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.	University Institute of Pathology
12852763	20	Computer-aided selection of potential antihypertensive compounds with dual mechanism of action.	Institute of Biomedical Chemistry of Russian Academy of Medical Sciences
12477342	27	2002 Alfred Burger Award Address in Medicinal Chemistry. Natural products and design: interrelated approaches in drug discovery.	Merck Research Laboratories
10669559	180	Protease inhibitors: current status and future prospects.	University of Queensland
10882358	62	Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.	F. Hoffmann-La Roche
10508425	68	Mixture-based synthetic combinatorial libraries.	Torrey Pines Institute For Molecular Studies
8021926	41	New thiol inhibitors of neutral endopeptidase EC 3.4.24.11: synthesis and enzyme active-site recognition.	University of Paris
8340909	14	Excursions in drug discovery.	Merck Research Laboratories
1995872	5	Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors.	University of Calgary
2160536	13	Angiotensin converting enzyme inhibitors. 10. Aryl sulfonamide substituted N-[1-carboxy-3-phenylpropyl]-L-alanyl-L-proline derivatives as novel antihypertensives.	Rorer Central Research
2544729	8	Angiotensin converting enzyme inhibitors: spirapril and related compounds.	Schering-Plough
2566685	47	Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements.	University of Wisconsin-Madison
2913292	23	Studies on angiotensin converting enzyme inhibitors. 4. Synthesis and angiotensin converting enzyme inhibitory activities of 3-acyl-1-alkyl-2-oxoimidazolidine-4-carboxylic acid derivatives.	Tanabe Seiyaku
3005569	17	Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations.	TBA
3020249	29	Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.	TBA
2993618	19	Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme.	TBA
2983076	2	Conformational analysis and active site modelling of angiotensin-converting enzyme inhibitors.	TBA
2999394	21	Angiotensin converting enzyme inhibitors: structure-activity profile of 1-benzazepin-2-one derivatives.	TBA
6173481	24	Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors.	TBA
6259352	8	Synthesis and angiotensin-converting enzyme inhibitory activity of 3-(Mercaptomethyl)-2-oxo-1-pyrrolidineacetic acids and 3-(Mercaptomethyl)-2-oxo-1-piperidineacetic acids.	TBA
	66	Dual inhibition of neutral endopeptidase and angiotensin-converting enzyme by N-phosphonomethyl and N-carboxyalkyl dipeptides	TBA
	20	4-Substituted proline derivatives that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11.	TBA
	11	Thiol and hydroxamic acid containing inhibitors of endothelin converting enzyme	TBA
19949058	15	Blockade of X4-tropic HIV-1 cellular entry by GSK812397, a potent noncompetitive CXCR4 receptor antagonist.	Glaxosmithkline
19899765	69	Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.	Cea
19703773	63	The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.	Gsk Medicines Research Centre
1517742	9	Inhibition of Angiotensin-I-Converting Enzyme by Tetrahydroxyxanthones Isolated from Tripterospermum lanceolatum	TBA
	23	Novel low molecular renin inhibitors which show good oral blood pressure lowering effects in marmosets	TBA
	27	Dual inhibition of angiotensin-converting enzyme and neutral endopeptidase by tricyclic benzazepinone thiols	TBA
	28	α-Mercaptoacyl dipeptides that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11	TBA
	5	Peptide mimics of glycylproline as inhibitors of prolidase	TBA
	7	The design of a dipeptide library for screening at peptide receptor sites	TBA
	2	Synthesis of 6-amino-5-oxo-7-phenyl-1,4-oxazepines as conformationally constrained gauche (−) dipeptide mimetics	TBA
	1	An acyliminium ion route to Cis and Trans "Anti" phe-gly dipeptide mimetics	TBA
19042128	76	Synthesis and biological evaluation of N-mercaptoacylcysteine derivatives as leukotriene A4 hydrolase inhibitors.	Santen Pharmaceutical
18790648	317	Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.	University of Athens
18701300	55	Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides.	University of Leipzig
18674901	32	Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.	Santen Pharmaceutical
16784850	14	Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors.	University of Cape Town
16784843	4	Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme.	University of Cape Town
16464585	4	Structure-activity relationship study between Ornithyl-Proline and Lysyl-Proline based tripeptidomimics as angiotensin-converting enzyme inhibitors.	Institute of Genomics and Integrative Biology
11551755	18	Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.	British Biotech Pharmaceuticals
11384231	26	2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.	F. Hoffmann-La Roche
27563406	128	Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.	Roche Pharma Research and Early Development
32337993	11	Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme.	University of Bath
30300845	43	1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.	Universit£
9484512	130	Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives.	Shionogi
9046341	44	Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.	Ciba-Geigy
30655952	89	Discovery of TD-0212, an Orally Active Dual Pharmacology AT	Theravance Biopharma Us
8421293	32	Exploration of neutral endopeptidase active site by a series of new thiol-containing inhibitors.	University of Paris
24088053	11	Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching.	E£Tv£S Lor£Nd University
24095015	4	Perindopril and ramipril phosphonate analogues as a new class of angiotensin converting enzyme inhibitors.	Universit£
8057292	83	Mercaptoacyl amino acid inhibitors of atriopeptidase. 1. Structure-activity relationship studies of methionine and S-alkylcysteine derivatives.	Schering-Plough Research Institute
7966160	7	PRO_LIGAND: an approach to de novo molecular design. 2. Design of novel molecules from molecular field analysis (MFA) models and pharmacophores.	Proteus Molecular Design
16889963	3	The molecular basis for the selection of captopril cis and trans conformations by angiotensin I converting enzyme.	Mrc Laboratory of Molecular Biology, Hills Road, Cambridge, Cb2 2Qh
6288947	6	Angiotensin converting enzyme inhibitors: modifications of a tripeptide analogue.	TBA
30372620	8	Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.	University of Bath
29039662	62	Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds.	Csir-National Chemical Laboratory
29405714	4	Metabolomics-Guided Discovery of Microginin Peptides from Cultures of the Cyanobacterium Microcystis aeruginosa.	University of North Carolina Wilmington
29032034	13	Therapeutic investigations of novel indoxyl-based indolines: A drug target validation and Structure-Activity Relationship of angiotensin-converting enzyme inhibitors with cardiovascular regulation and thrombolytic potential.	Vit University
28442252	62	Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome.	Ranbaxy Laboratories
1331459	1	The first mechanism-based inactivators for angiotensin-converting enzyme.	Baxter Diagnostics