The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28165742 |
14 |
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity. |
Universit£ |
| 27541271 |
247 |
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. |
Genentech |
| 27158141 |
11 |
Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies. |
Charles River Laboratories |
| 26755394 |
14 |
Identification of benzothiophene amides as potent inhibitors of human nicotinamide phosphoribosyltransferase. |
Second Military Medical University |
| 25556090 |
99 |
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility. |
Genentech |
| 24021463 |
37 |
Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). |
Forma Therapeutics |
| 24900822 |
4 |
Thiazolocarboxamide Analogues as NAMPT Inhibitors. |
Dart Neuroscience |
| 24405419 |
96 |
Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). |
Genentech |
| 24433859 |
80 |
Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). |
Genentech |
| 24279990 |
14 |
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. |
Forma Therapeutics |
| 24164086 |
17 |
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship. |
Topotarget |
| 23679915 |
11 |
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. |
Universit£ |
| 23899614 |
60 |
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). |
Genentech |
| 23859118 |
60 |
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors. |
Forma Therapeutics |
| 23668988 |
81 |
Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties. |
Genentech |
| 23617784 |
74 |
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors. |
Forma Therapeutics |
| 21080724 |
57 |
Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt). |
Myrexis |
| 21330015 |
2 |
Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents. |
School of Life Science |
| 31818629 |
2 |
Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. |
Gazi University |
| 27224875 |
46 |
Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities. |
Chinese Academy of Sciences |
| 31749905 |
20 |
Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT). |
Novartis Institute For Biomedical Research |
| 30992165 |
21 |
Discovery of trans-3-(pyridin-3-yl)acrylamide-derived sulfamides as potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for the potential treatment of cancer. |
Chinese Academy of Sciences |
| 31938461 |
20 |
Nicotinamide Phosphoribosyltransferase (NAMPT) Is a New Target of Antitumor Agent Chidamide. |
Second Military Medical University |
| 29348808 |
35 |
Dual NAMPT/HDAC Inhibitors as a New Strategy for Multitargeting Antitumor Drug Discovery. |
Second Military Medical University |
| 28610984 |
51 |
SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT). |
Abbvie |
| 28885834 |
80 |
Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. |
Second Military Medical University |
| 24648521 |
2 |
Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance. |
St. Paul'S Hospital'S Centre of Heart and Lung Innovation |
| 12365460 |
11 |
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study. |
University of Porto-Rua Anibal Cunha |
| 11906289 |
87 |
Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP). |
Cnrs |
| 1375293 |
42 |
Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 2. Tricyclic pyridobenzoxazepinones and dibenzoxazepinones. |
Boehringer Ingelheim Pharmaceuticals |
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