The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 26810316 |
29 |
Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. |
Merck Research Laboratories |
| 25254640 |
64 |
Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2. |
Syntrix Biosystems |
| 24075145 |
17 |
Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate. |
Glaxosmithkline |
| 23403082 |
28 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. |
Broad Institute of Mit and Harvard |
| 15922596 |
7 |
Novel phomactin analogues as PAF receptor ligands. |
The University of Nottingham |
| 16220969 |
219 |
Designed multiple ligands. An emerging drug discovery paradigm. |
Organon Laboratories |
| 1404229 |
15 |
Development, synthesis, and biological evaluation of (-)-trans-(2S,5S)-2-[3-[(2-oxopropyl)sulfonyl]-4-n-propoxy-5-(3- hydroxypropoxy)-phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent orally active platelet-activating factor (PAF) antagonist and its water-soluble prodrug phosphate ester. |
Merck Research Laboratories |
| 9871752 |
4 |
A 3D-QSAR study on ginkgolides and their analogues with comparative molecular field analysis. |
Chinese Academy of Sciences |
| | 19 |
Cyclic ether acetal platelet activating factor (PAF) receptor antagonists II: imidazo[4,5-c]pyridyl derivatives |
TBA |
| | 28 |
Cyclic ether acetal platelet activating factor (PAF) receptor antagonists I: 3-pyridyl derivatives |
TBA |
| | 8 |
A partial pharmacophore for the platelet activating factor (PAF) receptor |
TBA |
| | 4 |
Synthesis and biological activity of the platelet-activating factor antagonist ()-trans-2-(3-methoxy-4-phenylsulfonylethoxy-5-n-propylsulfonylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-671,284) and its analogs |
TBA |
| | 7 |
Synthesis and biological activity of MK 287 (L-680,573): a potent, specific and orally active paf receptor antagonist |
TBA |
| | 42 |
Cmi-206: A potent dual platelet activating factor antagonist and 5-lipoxygenase inhibitor |
TBA |
| | 18 |
Enantiodifferentiation of dihydropyridine PAF antagonists |
TBA |
| 16722655 |
28 |
Discovery of a novel, orally active, small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist. |
Pfizer |
| 9599246 |
28 |
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist. |
University of Virginia |
| 8230095 |
11 |
Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. |
Sandoz Research Institute |
| 7830265 |
34 |
Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines. |
Sandoz Research Institute |
| 3339617 |
34 |
Pyrido[2,1-b]quinazolinecarboxamide derivatives as platelet activating factor antagonists. |
Hoffmann-La Roche |
| 2754709 |
57 |
Pentadienyl carboxamide derivatives as antagonists of platelet-activating factor. |
Roche Research Center |
| 2754708 |
27 |
Biphenylcarboxamide derivatives as antagonists of platelet-activating factor. |
Roche Research Center |
| 2170651 |
13 |
Propenyl carboxamide derivatives as antagonists of platelet activating factor. |
Hoffmann-La Roche |
| 2016721 |
35 |
Thienotriazolodiazepines as platelet-activating factor antagonists. Steric limitations for the substituent in position 2. |
Roche Research Center |
| 2002463 |
78 |
Triazolobenzo- and triazolothienodiazepines as potent antagonists of platelet activating factor. |
Roche Research Center |
| 1671420 |
49 |
Dual antagonists of platelet activating factor and histamine. Identification of structural requirements for dual activity of N-Acyl-4-(5,6-dihydro-11H-benzo [5,6]cyclohepta-[1,2-b]pyridin-11-ylidene)piperidines. |
Schering-Plough |
| 26833890 |
18 |
Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease. |
Yogi Vemana University |
| 26469307 |
7 |
Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b. |
University of Leipzig |
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