The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
12639549 |
2 |
Inhibition of inosine monophosphate dehydrogenase (IMPDH) by 2-[2-(Z)-fluorovinyl]inosine 5'-monophosphate. |
The University of Georgia |
12729643 |
31 |
Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening. |
Roche Discovery Welwyn |
24900625 |
52 |
Design and Discovery of 2-Arylquinazolin-4-ones as Potent and Selective Inhibitors of Tankyrases. |
University of Bath |
23668331 |
120 |
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. |
Brandeis University |
20650640 |
24 |
Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure. |
University of Minnesota |
6142953 |
5 |
Inhibitors of inosinic acid dehydrogenase. 2-Substituted inosinic acids. |
TBA |
22950983 |
81 |
Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. |
Brandeis University |
22464133 |
5 |
Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07. |
Chinese Academy of Sciences |
22310229 |
102 |
Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. |
Brandeis University |
19624136 |
48 |
Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. |
Brandeis University |
11806722 |
14 |
Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
Pharmasset |
12014950 |
24 |
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity. |
TBA |
9484510 |
3 |
Synthesis of a methylenebis(phosphonate) analogue of mycophenolic adenine dinucleotide: a glucuronidation-resistant MAD analogue of NAD. |
Codon Pharmaceuticals |
9572896 |
20 |
Isosteric analogues of nicotinamide adenine dinucleotide derived from furanfurin, thiophenfurin, and selenophenfurin as mammalian inosine monophosphate dehydrogenase (type I and II) inhibitors. |
Universit£ |
9258359 |
9 |
Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity. |
Codon Pharmaceuticals |
9016322 |
10 |
Rationally designed inhibitors of inosine monophosphate dehydrogenase. |
University of Chicago |
22172700 |
6 |
The design, synthesis and in vitro immunosuppressive evaluation of novel isobenzofuran derivatives. |
Shenyang Pharmaceutical University |
21924610 |
3 |
Aminothiazoles as¿-secretase modulators. |
F. Hoffmann-La Roche |
21324702 |
40 |
Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. |
University of Minnesota |
20934342 |
14 |
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives. |
Hokkaido University |
20491506 |
8 |
Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. |
University of Minnesota |
18809333 |
14 |
Mycophenolic acid analogs with a modified metabolic profile. |
University of Minnesota |
18583139 |
26 |
Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. |
University of Minnesota |
18038969 |
14 |
Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment. |
University of Minnesota |
17395461 |
2 |
Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor. |
University of Minnesota |
16884314 |
4 |
Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase. |
University of Minnesota |
16621550 |
27 |
Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH. |
Gilead Sciences |
16483773 |
24 |
Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships. |
Ucb Pharma |
16483769 |
15 |
Low molecular weight indole fragments as IMPDH inhibitors. |
Ucb Pharma |
16202581 |
21 |
Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors. |
Ucb Pharma |
15664851 |
14 |
Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships. |
Celltech R and D |
14505670 |
36 |
3-cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12781195 |
49 |
Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12657279 |
25 |
Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12657262 |
14 |
Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3. |
Bristol-Myers Squibb Pri |
12565969 |
36 |
Quinolone-based IMPDH inhibitors: introduction of basic residues on ring D and SAR of the corresponding mono, di and benzofused analogues. |
Bristol-Myers Squibb Pri |
12565968 |
40 |
Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series. |
Bristol-Myers Squibb Pri |
12392738 |
15 |
The TosMIC approach to 3-(oxazol-5-yl) indoles: application to the synthesis of indole-based IMPDH inhibitors. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12372516 |
14 |
A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12270177 |
23 |
Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
12270168 |
40 |
Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase. |
Bristol-Myers Squibb Pri |
12127522 |
30 |
Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
11965381 |
22 |
Novel diamide-based inhibitors of IMPDH. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
8863796 |
65 |
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid. |
Syntex Research |
24269162 |
84 |
NAD-based inhibitors with anticancer potential. |
University of Minnesota |
23937979 |
6 |
Discovery of N-(2,3,5-triazoyl)mycophenolic amide and mycophenolic epoxyketone as novel inhibitors of human IMPDH. |
Hokkaido University |
30223117 |
9 |
Discovery of novel human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents. |
Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management |
30322754 |
48 |
Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. |
The University of Queensland |
29746130 |
100 |
Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents. |
National Institute of Allergy and Infectious Diseases |