37 articles for thisTarget

---

The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27228159	2	Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.	Mahidol University
26287401	39	Lanostane Triterpenes from the Tibetan Medicinal Mushroom Ganoderma leucocontextum and Their Inhibitory Effects on HMG-CoA Reductase anda-Glucosidase.	Chinese Academy of Sciences
25022881	1	Molecular modeling studies of atorvastatin analogues as HMGR inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations.	Shanghai Institute of Technology
25311563	12	Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors.	Instituto Polit£Cnico Nacional (Ipn)
23570542	48	Design and synthesis of dual-action inhibitors targeting histone deacetylases and 3-hydroxy-3-methylglutaryl coenzyme A reductase for cancer treatment.	National Taiwan University
19879766	11	Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.	Institute of Pharmaceutical Industry
15686906	34	Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA).	National Institute of Pharmaceutical Education and Research (NIPER)
1527791	8	Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.	British Bio-Technology
1597859	14	Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones.	Warner-Lambert
1656041	75	Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.	Hoechst
21872367	2	Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.	Central Drug Research Institute (Csir)
20494585	27	Peptide fragmentation as an approach in modeling of an active peptide and designing a competitive inhibitory peptide for HMG-CoA reductase.	Institute of The Chemistry of Plant Substances
	11	Novel Acetylenic Acids from the Root Bark of Paramacrolobium caeruleum: Inhibitors of 3-Hydroxy-3-methyl-glutaryl Coenzyme A Reductase	TBA
	18	Synthesis of tetrazol-1-yl analogs of HMG-COA reductase inhibitor BMS180431 (formerly BMY21950)	TBA
	2	Phosphinic acid inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme a reductase	TBA
17574412	31	Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.	Pfizer
17574411	15	Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.	Pfizer
15686898	8	Molecular docking of the highly hypolipidemic agent alpha-asarone with the catalytic portion of HMG-CoA reductase.	Universidad Nacional AutóNoma De MéXico
11392538	2	Synthesis and biological evaluations of condensed pyridine and condensed pyrimidine-based HMG-CoA reductase inhibitors.	Central Research Institute
31902650	2	Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols.	The University of Tokyo
31573805	2	Bipolaricins A-I, Ophiobolin-Type Tetracyclic Sesterterpenes from a Phytopathogenic	Huazhong University of Science and Technology
31188592	39	Why Some Targets Benefit from beyond Rule of Five Drugs.	Boston University
8426367	10	32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis.	Institute
8057282	2	Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription.	Upjohn Laboratories
11170677	1	Synthesis of a novel lysophosphatidylcholine.	Graduate School of Okayama University
2296036	48	Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids.	Hoechst
2153213	29	Synthesis and biological activity of new HMG-CoA reductase inhibitors. 2. Derivatives of 7-(1H-pyrrol-3-yl)-substituted-3,5-dihydroxyhept-6(E)-enoic (-heptanoic) acids.	Hoechst
28850227	85	Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.	St. John'S University
1433193	7	3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.	Merck Research Laboratories
19875078	5	Discovery of potent and reversible monoacylglycerol lipase inhibitors.	University of California Irvine
19716475	20	Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.	Burnham Institute For Medical Research
19389627	2	Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.	Pfizer