47 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27769668	32	The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents.	Southern Research Institute
25799376	2	Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents.	Taipei Medical University
26312433	20	Design, synthesis and evaluation of thiohydantoin derivatives as potent topoisomerase I (Top1) inhibitors with anticancer activity.	Shiv Nadar University
25913198	2	Stereoselective synthesis of 11-phenylundeca-5Z,9Z-dienoic acid and investigation of its human topoisomerase I and IIa inhibitory activity.	Russian Academy of Science
15808469	32	Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships.	Kumamoto University
22305612	7	Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.	Dongguk University-Seoul
23092389	5	Lanostanoids from fungi: a group of potential anticancer compounds.	TBA
22867097	1	Inhibition of human topoisomerases I and II by simocyclinone D8.	University of Minnesota Medical School
21542600	4	Inverse virtual screening of antitumor targets: pilot study on a small database of natural bioactive compounds.	Universita Di Salerno
20662543	18	Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2.	Kaohsiung Medical University
20371180	122	Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides.	Stephen F. Austin State University
15974606	5	Indole alkaloids and other constituents of Rauwolfia serpentina.	Kobe Pharmaceutical University
18083028	5	Synthesis and biological evaluation of bengacarboline derivatives.	Universit£
15801827	4	Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex.	Decode Biostructures
10821712	18	Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity.	Neogenesis
9003520	15	Camptothecin and minor-groove binder hybrid molecules: synthesis, inhibition of topoisomerase I, and anticancer cytotoxicity in vitro.	University of Alberta
8691444	105	Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.	National Cancer Institute-Bethesda
7707314	23	Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs.	Glaxo Inc. Research Institute
8410981	63	Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.	Research Triangle Institute
22014228	10	Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis.	University of Thessaly
22014547	2	Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.	University of Cagliari
1324981	3	A Strategy for Identifying Novel, Mechanistically Unique Inhibitors of Topoisomerase I	TBA
	10	Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins	TBA
	9	Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives	TBA
	4	Novel A-ring modified camptothecins as topoisomerase I inhibitors	TBA
	1	The synthesis and evaluation of flexible analogues of the topoisomerase I inhibitor, camptothecin	TBA
19397324	63	Synthesis and biological activities of topoisomerase I inhibitors, 6-arylmethylamino analogues of edotecarin.	Tsukuba Research Institute
19254843	2	Synthesis of new camptothecin analogs with improved antitumor activities.	Chugai Pharmaceutical
12444712	3	Total synthesis and biological evaluation of (5Z,9Z)-5,9-hexadecadienoic acid, an inhibitor of human topoisomerase I.	University of Puerto Rico
11430001	72	Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba.	Kumamoto University
17194596	3	Synthesis, cytotoxicity, and DNA topoisomerase II inhibitory activity of benzofuroquinolinediones.	Ewha Womans University
15801816	15	Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11.	The Bristol-Myers Squibb Pharmaceutical Research Institute
15454230	16	Camptothecin analogs with bulky, hydrophobic substituents at the 7-position via a Grignard reaction.	Research Triangle Institute
15026047	29	Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship.	Kumamoto University
14980693	6	Synthesis, topoisomerase I inhibition and structure-activity relationship study of 2,4,6-trisubstituted pyridine derivatives.	Liaoning Normal University
10743939	63	Synthesis and biological activities of NB-506 analogues modified at the glucose group.	Banyu Tsukuba Research Institute
10612590	56	Synthesis and biological activities of NB-506 analogues: Effects of the positions of two hydroxyl groups at the indole rings.	Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
10476878	8	Naphthazarin derivatives (II): formation of glutathione conjugate, inhibition of DNA topoisomerase-I and cytotoxicity.	Chungnam National University
10340602	100	Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506.	Banyu Tsukuba Research Institute
10021917	4	Indolocarbazole poisons of human topoisomerase I: regioisomeric analogues of ED-110.	Medichem Research
8576914	14	Water soluble inhibitors of topoisomerase I: quaternary salt derivatives of camptothecin.	Glaxo Wellcome Research Institute
7853331	7	Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I.	Glaxo Research Institute
7752206	20	Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines.	Stanford University Medical School
7699706	34	Rigid analogs of camptothecin as DNA topoisomerase I inhibitors.	Glaxo Research Institute
7699697	34	Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I.	Chungnam National University
28513176	5	Selective Inhibition of Escherichia coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono- and Bisbenzimidazoles.	Clemson University