Enzyme Monomer Search

Marvin 2D Structure

Wt: 409.4 BDBM50174833	Wt: 393.4 BDBM50174834	Wt: 393.4 BDBM50174835	Wt: 239.2 BDBM50174836	Wt: 409.4 BDBM50174837
Wt: 255.2 BDBM50174838

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 26 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trans-sialidase (Trypanosoma cruzi)	BDBM50174833 (CHEMBL199442 \| N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.70E+3	-32.0	2.50E+3	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
University of British Columbia					More data for this Ligand-Target Pair
Trans-sialidase (Trypanosoma cruzi)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.60E+3	-31.5	900	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
University of British Columbia					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Functional Crop Curated by ChEMBL					Assay Description Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot analysis				Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM
Department of Functional Crop Curated by ChEMBL					More data for this Ligand-Target Pair
Trans-sialidase (Trypanosoma cruzi)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi trans-sialidase using CF3MuSA as substrate by UV/visible spectrophotometric method				Eur J Med Chem 158: 25-33 (2018) Article DOI: 10.1016/j.ejmech.2018.08.089 BindingDB Entry DOI: 10.7270/Q2J105TR
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174833 (CHEMBL199442 \| N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Functional Crop Curated by ChEMBL					Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysis				Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM
Department of Functional Crop Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174833 (CHEMBL199442 \| N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Trans-sialidase (Trypanosoma cruzi)	BDBM50174834 (CHEMBL382280 \| N-(3-(3-(4-hydroxyphenyl)acryloyl)p...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
University of British Columbia					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174834 (CHEMBL382280 \| N-(3-(3-(4-hydroxyphenyl)acryloyl)p...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium channel subfamily K member 10 (Rattus norvegicus)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of rat TREK2 channel -mediated current expressed in HEK293 at 60 mV holding potential by patch clamp method				Bioorg Med Chem Lett 20: 4237-9 (2010) Article DOI: 10.1016/j.bmcl.2010.05.033 BindingDB Entry DOI: 10.7270/Q25Q4ZXM
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Trans-sialidase (Trypanosoma cruzi)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	7.6	35
University of British Columbia					Assay Description Inhibition assay using trans-sialidase, a membrane-associated protein.				Chembiochem 10: 2475-9 (2009) Article DOI: 10.1002/cbic.200900108 BindingDB Entry DOI: 10.7270/Q2MG7N10
University of British Columbia					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bos taurus)	BDBM50174834 (CHEMBL382280 \| N-(3-(3-(4-hydroxyphenyl)acryloyl)p...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bos taurus)	BDBM50174833 (CHEMBL199442 \| N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bos taurus)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bos taurus)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Alpha-mannosidase (Canavalia ensiformis)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Alpha-mannosidase (Canavalia ensiformis)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Alpha-mannosidase (Canavalia ensiformis)	BDBM50174833 (CHEMBL199442 \| N-(3-(3-(3,4-dihydroxyphenyl)acrylo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Alpha-mannosidase (Canavalia ensiformis)	BDBM50174834 (CHEMBL382280 \| N-(3-(3-(4-hydroxyphenyl)acryloyl)p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174838 (1-(4-aminophenyl)-3-(3,4-dihydroxyphenyl)prop-2-en...) Show SMILES Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-amylase (Bacillus licheniformis)	BDBM50174837 (4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone \|...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against Bacillus licheniformis alpha amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174834 (CHEMBL382280 \| N-(3-(3-(4-hydroxyphenyl)acryloyl)p...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174836 (1-(3-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-o...) Show SMILES Nc1cccc(c1)C(=O)\C=C\c1ccc(O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-amylase (Hordeum vulgare)	BDBM50174835 (4'-(4-toluenesulfonamido)-4-hydroxychalcone \| 4'-(...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.47E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibitory activity against barley beta amylase				Bioorg Med Chem Lett 15: 5514-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.087 BindingDB Entry DOI: 10.7270/Q2FX7B6F
Gyeongsang National University Curated by ChEMBL					More data for this Ligand-Target Pair