Enzyme Monomer Search

Marvin 2D Structure

Wt: 199.1 BDBM50021959 Purchase	Wt: 340.0 BDBM50315411	Wt: 413.3 BDBM50347180	Wt: 558.6 BDBM50347181	Wt: 397.3 BDBM50347182
Wt: 397.3 BDBM50347183	Wt: 397.3 BDBM50347184	Wt: 383.2 BDBM50347185	Wt: 278.2 BDBM50347186	Wt: 278.2 BDBM50347187
Wt: 502.4 BDBM50347188	Wt: 321.3 BDBM50486723	Wt: 307.3 BDBM50486724	Wt: 510.4 BDBM50486725

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 139 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-CERCOA Curated by ChEMBL					Assay Description Inhibition constant (Ki) for TEM-1 beta-lactamase				J Med Chem 31: 370-4 (1988) BindingDB Entry DOI: 10.7270/Q21R6PHS
CNRS-CERCOA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase SHV-5 (Klebsiella pneumoniae)	BDBM50486725 (CHEMBL2236666) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-105				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+3	n/a	100	n/a	n/a	n/a	n/a	7.4	n/a
Case Western Reserve University					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...				Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW
Case Western Reserve University					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486725 (CHEMBL2236666) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Mycobacterium tuberculosis H37Rv)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Indian Institute of Technology					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in sodium phosphate buffer (50 mM, pH 7.2) and a 1 cm pathlengt...				Biochemistry 54: 5657-64 (2015) Article DOI: 10.1021/acs.biochem.5b00698 BindingDB Entry DOI: 10.7270/Q29W0D7G
Indian Institute of Technology					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assay				Antimicrob Agents Chemother 54: 2867-77 (2010) Article DOI: 10.1128/AAC.00197-10 BindingDB Entry DOI: 10.7270/Q2QJ7HJP
Case Western Reserve University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50486725 (CHEMBL2236666) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Citrobacter freundii beta-lactamase SHV-95				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50486725 (CHEMBL2236666) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Acinetobacter baumannii beta-lactamase SHV-48				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-5 (Klebsiella pneumoniae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-105				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-5 (Klebsiella pneumoniae)	BDBM50486724 (PENEM-1) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-105				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50486723 (PENEM-2) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Citrobacter freundii beta-lactamase SHV-95				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50486723 (PENEM-2) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Acinetobacter baumannii beta-lactamase SHV-48				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50486724 (PENEM-1) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	4.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Citrobacter freundii beta-lactamase SHV-95				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50486724 (PENEM-1) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	5.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Acinetobacter baumannii beta-lactamase SHV-48				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486723 (PENEM-2) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	6.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-5 (Klebsiella pneumoniae)	BDBM50486723 (PENEM-2) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-105				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Citrobacter freundii beta-lactamase SHV-95				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486724 (PENEM-1) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	2.27E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Acinetobacter baumannii beta-lactamase SHV-48				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50347184 (CHEMBL1795567) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta lactamase AmpC				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter gillenii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
H�pital de Bic�tre Curated by ChEMBL					Assay Description Inhibition of Citrobacter gillenii CIP 106783 Beta-lactamase GIL1 expressed in Escherichia coli DH10B				Antimicrob Agents Chemother 51: 1365-72 (2007) Article DOI: 10.1128/AAC.01152-06 BindingDB Entry DOI: 10.7270/Q2S46SS7
H�pital de Bic�tre Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CTX-M-15				Antimicrob Agents Chemother 51: 3089-95 (2007) Article DOI: 10.1128/AAC.00218-07 BindingDB Entry DOI: 10.7270/Q2BG2NR1
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50347182 (CHEMBL1795565) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta lactamase AmpC				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Salmonella enterica subsp. enterica serovar Westha...)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de R£f£rence des Salmonella Curated by ChEMBL					Assay Description Inhibition of Salmonella enterica serotype Westhampton beta-lactamase CTX-M-53				Antimicrob Agents Chemother 53: 1944-51 (2009) Article DOI: 10.1128/AAC.01581-08 BindingDB Entry DOI: 10.7270/Q2445MRF
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against Escherichia coli TEM-3 Beta-lactamase				J Med Chem 41: 3961-71 (1998) Article DOI: 10.1021/jm980023c BindingDB Entry DOI: 10.7270/Q2HT2NF0
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella pneumoniae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-55				Antimicrob Agents Chemother 52: 1897-8 (2008) Article DOI: 10.1128/AAC.01525-07 BindingDB Entry DOI: 10.7270/Q2PV6KKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	20.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50347188 (CHEMBL1795571) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta lactamase AmpC				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50347188 (CHEMBL1795571) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta lactamase AmpC				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli SHV1				J Med Chem 50: 4113-21 (2007) Article DOI: 10.1021/jm0703237 BindingDB Entry DOI: 10.7270/Q2FF3T5F
Lek Pharmaceuticals d.d. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	29.5	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
NABRIVA THERAPEUTICS AG US Patent					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d. Curated by ChEMBL					Assay Description Inhibition of Escherichia coli TEM1				J Med Chem 50: 4113-21 (2007) Article DOI: 10.1021/jm0703237 BindingDB Entry DOI: 10.7270/Q2FF3T5F
Lek Pharmaceuticals d.d. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella oxytoca)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Klebsiella oxytoca HC7 Class-IV K1 type beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase BRO-1 (Moraxella catarrhalis)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Branhamella catarrhalis 89001 Class-III BRO-1 type beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	30.3	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
NABRIVA THERAPEUTICS AG US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50347184 (CHEMBL1795567) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae beta lactamase P99				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas luteola)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Institut Pasteur Curated by ChEMBL					Assay Description Inhibition of Pseudomonas luteola LAM Beta-lactamase LUT-1				Antimicrob Agents Chemother 54: 45-51 (2010) Article DOI: 10.1128/AAC.00427-09 BindingDB Entry DOI: 10.7270/Q2KS6VCC
Institut Pasteur Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50347182 (CHEMBL1795565) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae beta lactamase P99				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for beta-lactamase inhibition activity of Escherichia coli after 15 min of preincubation with the enzyme at 37 degree C				Bioorg Med Chem Lett 7: 2217-2222 (1997) Article DOI: 10.1016/S0960-894X(97)00401-0 BindingDB Entry DOI: 10.7270/Q2M32VR6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	40.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Escherichia coli HA58R Class-III TEM-1 type beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50347183 (CHEMBL1795566) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta lactamase AmpC				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against beta-Lactamase enzyme derived from Escherichia coli WC3310 TEM-2				Bioorg Med Chem Lett 5: 1513-1518 (1995) Article DOI: 10.1016/0960-894X(95)00249-S BindingDB Entry DOI: 10.7270/Q2ZW1MDG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Proteus mirabilis)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	65.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Proteus vulgaris HJ33C Class-I beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Institut Pasteur Hellenique Curated by ChEMBL					Assay Description Inhibition of Escherichia coli beta-lactamase SCO1				Antimicrob Agents Chemother 51: 2185-8 (2007) Article DOI: 10.1128/AAC.01439-06 BindingDB Entry DOI: 10.7270/Q2028SFP
Institut Pasteur Hellenique Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase TEM (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
CHU Clermont-Ferrand Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DH5alpha beta-lactamase TEM-1				Antimicrob Agents Chemother 51: 4181-3 (2007) Article DOI: 10.1128/AAC.00614-07 BindingDB Entry DOI: 10.7270/Q2H131TX
CHU Clermont-Ferrand Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against Penicillinase from Staphylococcus aureus TH-14 using piperacillin (40 uM) as a substrate				J Med Chem 30: 1469-74 (1987) BindingDB Entry DOI: 10.7270/Q28G8JQ0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Class A beta-lactamase BCL-1 (Bacillus clausii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
H�pital de Bic�tre Curated by ChEMBL					Assay Description Inhibition of Bacillus clausii NR beta-lactamase BCL1 expressed in Escherichia coli BL21 (DE3)				Antimicrob Agents Chemother 51: 4009-14 (2007) Article DOI: 10.1128/AAC.00537-07 BindingDB Entry DOI: 10.7270/Q20R9QBS
H�pital de Bic�tre Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50347188 (CHEMBL1795571) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae beta lactamase P99				Bioorg Med Chem Lett 21: 4363-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.122 BindingDB Entry DOI: 10.7270/Q24Q7V94
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair

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