Compile Data Set for Download or QSAR

Found 74 hits with Last Name = 'haase' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002173 (3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...) Show SMILES Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 |c:15| Show InChI InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366263 (CHEMBL45535) Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(OC(F)(F)F)cc2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C23H23F3N2O6/c24-23(25,26)34-17-4-2-16(3-5-17)28-13-18(33-21(28)29)12-27-9-7-22(30,8-10-27)15-1-6-19-20(11-15)32-14-31-19/h1-6,11,18,30H,7-10,12-14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002158 (5-Fluoro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 |c:15| Show InChI InChI=1S/C23H25FN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002175 (6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...) Show SMILES COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 |c:14| Show InChI InChI=1S/C24H28N2O/c1-27-22-10-11-23-21(18-25-24(23)17-22)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366262 (CHEMBL417353) Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(OCC3CC3)cc2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H30N2O6/c29-25-28(20-4-6-21(7-5-20)31-16-18-1-2-18)15-22(34-25)14-27-11-9-26(30,10-12-27)19-3-8-23-24(13-19)33-17-32-23/h3-8,13,18,22,30H,1-2,9-12,14-17H2/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002169 (3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]...) Show SMILES Oc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 |c:13| Show InChI InChI=1S/C23H26N2O/c26-21-9-10-22-20(17-24-23(22)16-21)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366274 (CHEMBL47715) Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(Cl)cc2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H23ClN2O5/c23-16-2-4-17(5-3-16)25-13-18(30-21(25)26)12-24-9-7-22(27,8-10-24)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,27H,7-10,12-14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002160 (5-Chloro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...) Show SMILES Clc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 |c:15| Show InChI InChI=1S/C23H25ClN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002174 (3-{4-[4-(2-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Fc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25FN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002176 (3-[6-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-hexyl]...) Show SMILES C(CCCc1c[nH]c2ccccc12)CCN1CCC(=CC1)c1ccccc1 |c:20| Show InChI InChI=1S/C25H30N2/c1(4-12-23-20-26-25-14-8-7-13-24(23)25)2-9-17-27-18-15-22(16-19-27)21-10-5-3-6-11-21/h3,5-8,10-11,13-15,20,26H,1-2,4,9,12,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002177 (5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 |c:16| Show InChI InChI=1S/C24H28N2O/c1-27-22-10-11-24-23(17-22)21(18-25-24)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366265 (CHEMBL47774) Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccccc2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H24N2O5/c25-21-24(17-4-2-1-3-5-17)14-18(29-21)13-23-10-8-22(26,9-11-23)16-6-7-19-20(12-16)28-15-27-19/h1-7,12,18,26H,8-11,13-15H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002162 (2-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...) Show SMILES Cc1[nH]c2ccccc2c1CCCCN1CCC(=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C24H28N2/c1-19-22(23-12-5-6-13-24(23)25-19)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,25H,7-8,11,15-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002172 (3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]...) Show SMILES C(CCc1c[nH]c2ccccc12)CN1CCC(=CC1)c1ccccc1 |c:18| Show InChI InChI=1S/C23H26N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-13,18,24H,6-7,10,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366273 (CHEMBL417357) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccccc2)OC1=O Show InChI InChI=1S/C22H26N2O4/c1-27-19-9-7-18(8-10-19)24-16-20(28-21(24)25)15-23-13-11-22(26,12-14-23)17-5-3-2-4-6-17/h2-10,20,26H,11-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366269 (CHEMBL47714) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(OC)cc2)OC1=O Show InChI InChI=1S/C23H28N2O5/c1-28-19-7-3-17(4-8-19)23(27)11-13-24(14-12-23)15-21-16-25(22(26)30-21)18-5-9-20(29-2)10-6-18/h3-10,21,27H,11-16H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002170 (3-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)Cc1c[nH]c2ccccc12 |c:5| Show InChI InChI=1S/C22H24N2/c1-2-7-18(8-3-1)19-12-15-24(16-13-19)14-6-9-20-17-23-22-11-5-4-10-21(20)22/h1-5,7-8,10-12,17,23H,6,9,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002167 (3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl...) Show SMILES C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12 |c:6| Show InChI InChI=1S/C24H28N2/c1-3-9-20(10-4-1)21-14-17-26(18-15-21)16-8-2-5-11-22-19-25-24-13-7-6-12-23(22)24/h1,3-4,6-7,9-10,12-14,19,25H,2,5,8,11,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366258 (CHEMBL44604) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(F)cc2)OC1=O Show InChI InChI=1S/C22H25FN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366275 (CHEMBL417181) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(Cl)c(c2)C(F)(F)F)OC1=O Show InChI InChI=1S/C23H24ClF3N2O4/c1-32-17-5-3-16(4-6-17)29-14-18(33-21(29)30)13-28-10-8-22(31,9-11-28)15-2-7-20(24)19(12-15)23(25,26)27/h2-7,12,18,31H,8-11,13-14H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002171 (3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002159 (1-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...) Show SMILES Cn1cc(CCCCN2CCC(=CC2)c2ccccc2)c2ccccc12 |c:11| Show InChI InChI=1S/C24H28N2/c1-25-19-22(23-12-5-6-13-24(23)25)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,19H,7-8,11,15-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366253 (CHEMBL50771) Show SMILES CCOc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O Show InChI InChI=1S/C24H28N2O6/c1-2-29-19-6-4-18(5-7-19)26-15-20(32-23(26)27)14-25-11-9-24(28,10-12-25)17-3-8-21-22(13-17)31-16-30-21/h3-8,13,20,28H,2,9-12,14-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366277 (CHEMBL48075) Show SMILES OC1(CCN(C[C@H]2CN(C(=O)O2)c2ccc(F)cc2)CC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H23FN2O5/c23-16-2-4-17(5-3-16)25-13-18(30-21(25)26)12-24-9-7-22(27,8-10-24)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,27H,7-10,12-14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366254 (CHEMBL296504) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC(C)(C)Oc3c2)OC1=O Show InChI InChI=1S/C25H30N2O6/c1-24(2)32-21-9-4-17(14-22(21)33-24)25(29)10-12-26(13-11-25)15-20-16-27(23(28)31-20)18-5-7-19(30-3)8-6-18/h4-9,14,20,29H,10-13,15-16H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366260 (CHEMBL295891) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCCc3c2)OC1=O Show InChI InChI=1S/C24H28N2O5/c1-29-20-5-3-19(4-6-20)26-16-21(31-23(26)27)15-25-11-9-24(28,10-12-25)18-2-7-22-17(14-18)8-13-30-22/h2-7,14,21,28H,8-13,15-16H2,1H3/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366251 (CHEMBL46438) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(OC)c(OC)c2)OC1=O Show InChI InChI=1S/C24H30N2O6/c1-29-19-7-5-18(6-8-19)26-16-20(32-23(26)27)15-25-12-10-24(28,11-13-25)17-4-9-21(30-2)22(14-17)31-3/h4-9,14,20,28H,10-13,15-16H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366268 (CHEMBL298492) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(C)cc2)OC1=O Show InChI InChI=1S/C23H28N2O4/c1-17-3-5-18(6-4-17)23(27)11-13-24(14-12-23)15-21-16-25(22(26)29-21)19-7-9-20(28-2)10-8-19/h3-10,21,27H,11-16H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366267 (CHEMBL45686 | Panamesine) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O Show InChI InChI=1S/C23H26N2O6/c1-28-18-5-3-17(4-6-18)25-14-19(31-22(25)26)13-24-10-8-23(27,9-11-24)16-2-7-20-21(12-16)30-15-29-20/h2-7,12,19,27H,8-11,13-15H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366257 (CHEMBL48124) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(CC2)c2ccc3OCOc3c2)OC1=O Show InChI InChI=1S/C23H26N2O5/c1-27-19-5-3-18(4-6-19)25-14-20(30-23(25)26)13-24-10-8-16(9-11-24)17-2-7-21-22(12-17)29-15-28-21/h2-7,12,16,20H,8-11,13-15H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366276 (CHEMBL45849) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc(Cl)cc2)OC1=O Show InChI InChI=1S/C22H25ClN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002165 (3-{4-[4-(2-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Clc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25ClN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366271 (CHEMBL45968) Show SMILES Oc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O Show InChI InChI=1S/C22H24N2O6/c25-17-4-2-16(3-5-17)24-13-18(30-21(24)26)12-23-9-7-22(27,8-10-23)15-1-6-19-20(11-15)29-14-28-19/h1-6,11,18,25,27H,7-10,12-14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366261 (CHEMBL47678) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCCOc3c2)OC1=O Show InChI InChI=1S/C24H28N2O6/c1-29-19-5-3-18(4-6-19)26-16-20(32-23(26)27)15-25-10-8-24(28,9-11-25)17-2-7-21-22(14-17)31-13-12-30-21/h2-7,14,20,28H,8-13,15-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366255 (CHEMBL45962) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccsc2)OC1=O Show InChI InChI=1S/C20H24N2O4S/c1-25-17-4-2-16(3-5-17)22-13-18(26-19(22)23)12-21-9-7-20(24,8-10-21)15-6-11-27-14-15/h2-6,11,14,18,24H,7-10,12-13H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366256 (CHEMBL297634) Show SMILES COc1ccc(cc1)N1C[C@@H](CN2CCC(O)(CC2)c2ccccc2)OC1=O Show InChI InChI=1S/C22H26N2O4/c1-27-19-9-7-18(8-10-19)24-16-20(28-21(24)25)15-23-13-11-22(26,12-14-23)17-5-3-2-4-6-17/h2-10,20,26H,11-16H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366264 (CHEMBL295039) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2cccs2)OC1=O Show InChI InChI=1S/C20H24N2O4S/c1-25-16-6-4-15(5-7-16)22-14-17(26-19(22)23)13-21-10-8-20(24,9-11-21)18-3-2-12-27-18/h2-7,12,17,24H,8-11,13-14H2,1H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor of guinea pig brain by using [3H]SKF-10047 radioligand				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002168 (3-{4-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-...) Show SMILES COc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:9| Show InChI InChI=1S/C24H28N2O/c1-27-22-11-9-19(10-12-22)20-13-16-26(17-14-20)15-5-4-6-21-18-25-24-8-3-2-7-23(21)24/h2-3,7-13,18,25H,4-6,14-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002166 (3-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Clc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25ClN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50026045 ((R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC Show InChI InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366270 (CHEMBL47279) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC4(CCCC4)Oc3c2)OC1=O Show InChI InChI=1S/C27H32N2O6/c1-32-21-7-5-20(6-8-21)29-18-22(33-25(29)30)17-28-14-12-26(31,13-15-28)19-4-9-23-24(16-19)35-27(34-23)10-2-3-11-27/h4-9,16,22,31H,2-3,10-15,17-18H2,1H3/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50002238 ((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...) Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002163 (3-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]...) Show SMILES C(Cc1c[nH]c2ccccc12)N1CCC(=CC1)c1ccccc1 |c:16| Show InChI InChI=1S/C21H22N2/c1-2-6-17(7-3-1)18-10-13-23(14-11-18)15-12-19-16-22-21-9-5-4-8-20(19)21/h1-10,16,22H,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002164 (3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole | ...) Show SMILES C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C23H28N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-12,18,20,24H,6-7,10,13-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366250 (CHEMBL46496) Show SMILES COc1ccc(cc1)N1C[C@@H](CN2CCC(O)(CC2)c2ccc(OC)cc2)OC1=O Show InChI InChI=1S/C23H28N2O5/c1-28-19-7-3-17(4-8-19)23(27)11-13-24(14-12-23)15-21-16-25(22(26)30-21)18-5-9-20(29-2)10-6-18/h3-10,21,27H,11-16H2,1-2H3/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366272 (CHEMBL289645) Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(=CC2)c2ccc3OCOc3c2)OC1=O |c:16| Show InChI InChI=1S/C23H24N2O5/c1-27-19-5-3-18(4-6-19)25-14-20(30-23(25)26)13-24-10-8-16(9-11-24)17-2-7-21-22(12-17)29-15-28-21/h2-8,12,20H,9-11,13-15H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366252 (CHEMBL47834) Show SMILES CC(=O)Oc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCOc3c2)OC1=O Show InChI InChI=1S/C24H26N2O7/c1-16(27)32-19-5-3-18(4-6-19)26-14-20(33-23(26)28)13-25-10-8-24(29,9-11-25)17-2-7-21-22(12-17)31-15-30-21/h2-7,12,20,29H,8-11,13-15H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366259 (CHEMBL46169) Show SMILES COc1ccc(cc1)N1C[C@@H](CN2CCC(O)(CC2)c2ccc(Cl)cc2)OC1=O Show InChI InChI=1S/C22H25ClN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50366266 (CHEMBL43783) Show SMILES COc1ccc(cc1)N1C[C@@H](CN2CCC(O)(CC2)c2ccc(F)cc2)OC1=O Show InChI InChI=1S/C22H25FN2O4/c1-28-19-8-6-18(7-9-19)25-15-20(29-21(25)26)14-24-12-10-22(27,11-13-24)16-2-4-17(23)5-3-16/h2-9,20,27H,10-15H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) Show SMILES C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 |r| Show InChI InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047				Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P
					More data for this Ligand-Target Pair

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