BindingDB PrimarySearch

Found 397 hits with Last Name = 'hirsch' and Initial = 'akh'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50589973 (CHEMBL5184569) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50589973 (CHEMBL5184569) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50462575 (CHEMBL4238121) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin) pre-incubated for 2 hrs before fluorescence substrate addition and measured after 5 mins by fluorescence as...				J Med Chem 61: 9395-9409 (2018) Article DOI: 10.1021/acs.jmedchem.8b00266 BindingDB Entry DOI: 10.7270/Q2765J0C
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Elastase (Pseudomonas aeruginosa)	BDBM50542712 (CHEMBL4647152) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI) Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa LasB using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as fluorogenic substrate by fluorimetric assay				J Med Chem 63: 8359-8368 (2020) Article DOI: 10.1021/acs.jmedchem.0c00584 BindingDB Entry DOI: 10.7270/Q20005N6
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553887 (CHEMBL4779696) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Collagenase ColQ1 (Bacillus cereus (strain Q1))	BDBM50589971 (CHEMBL5187038) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553872 (CHEMBL4794376) Show SMILES COc1ccc(cc1OC)N1Cc2ccc(O)cc2OC1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM11859 (2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Collagenase ColH (Hathewaya histolytica)	BDBM11859 (2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553880 (CHEMBL4761710) Show SMILES Oc1ccc2cc(-c3ccc(Br)cc3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50746 (5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assay				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553871 (CHEMBL1392132) Show SMILES COc1ccc(cc1)-c1cc2ccc(O)cc2oc1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553883 (CHEMBL4791357) Show SMILES Oc1ccc(cc1)-n1cc(nn1)-c1cc2ccccc2cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553874 (CHEMBL4797003) Show SMILES Cc1ccc(cc1)-c1cc2ccc(O)cc2oc1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553881 (CHEMBL4739944) Show SMILES Oc1ccc2cc(-c3ccc(I)cc3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50240685 (CHEMBL1522581) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description In vitro inhibitory activity against [3H]-DTG in guinea pig brain membrane homogenates				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50745 (3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assay				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553873 (CHEMBL3739747) Show SMILES Oc1ccc2cc(-c3ccc(Cl)cc3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Bifunctional ligase/repressor BirA (Staphylococcus aureus)	BDBM161470 (US9108978, 4.01) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus biotin protein ligase by LC/MS-SIM analysis				J Med Chem 61: 9395-9409 (2018) Article DOI: 10.1021/acs.jmedchem.8b00266 BindingDB Entry DOI: 10.7270/Q2765J0C
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ELAV-like protein 1 (Homo sapiens (Human))	BDBM51309 (5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-(4-morpholi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assay				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase ColQ1 (Bacillus cereus (strain Q1))	BDBM50589972 (CHEMBL5191074) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553886 (CHEMBL4741927) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50240684 (CHEMBL1309685) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assay				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM61111 (5,7-dimethoxy-8-[3-oxidanylidene-3-pyrrolidin-1-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 (unknown origin)-ARE sequence of Mushashi1 transcript complex formation after 2 hrs by fluorescence polarization assay				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50096003 (7-Hydroxy-3-phenyl-chromen-2-one \| 7-hydroxy-3-phe...) Show SMILES Oc1ccc2cc(-c3ccccc3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553876 (CHEMBL4800460) Show SMILES COc1cccc(c1)-c1cc2ccc(O)cc2oc1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553878 (CHEMBL4760818) Show SMILES Oc1ccc2cc(-c3cccc(Cl)c3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553875 (CHEMBL4798868) Show SMILES Oc1ccc2cc(-c3ccc4ccccc4c3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM51568 (3-(4-fluorophenyl)-7-hydroxy-1-benzopyran-2-one \| ...) Show SMILES Oc1ccc2cc(-c3ccc(F)cc3)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Collagenase ColH (Hathewaya histolytica)	BDBM50589972 (CHEMBL5191074) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553877 (CHEMBL1801021) Show SMILES COc1ccccc1-c1cc2ccc(O)cc2oc1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM11859 (2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553885 (CHEMBL4745151) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50746 (5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-oxidanylide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase ColA (Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)	BDBM50589971 (CHEMBL5187038) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50240520 ((isothiocyanatomethyl)benzene \| BITC, 17 \| Benzyls...) Show SMILES S=C=NCc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50240685 (CHEMBL1522581) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase ColA (Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)	BDBM50589972 (CHEMBL5191074) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553882 (CHEMBL4751935) Show SMILES Oc1ccc(cc1)-n1cc(nn1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50745 (3-(5,7-dimethoxy-2-oxidanylidene-4-phenyl-chromen-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM51309 (5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-(4-morpholi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50240684 (CHEMBL1309685) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM61111 (5,7-dimethoxy-8-[3-oxidanylidene-3-pyrrolidin-1-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Inhibition of ELAV1 RRM1/RRM2 domains (unknown origin) interaction with ARE sequence of Mushashi1 transcript after 2 hrs by AlphaLISA method				J Med Chem 60: 8257-8267 (2017) Article DOI: 10.1021/acs.jmedchem.6b01871 BindingDB Entry DOI: 10.7270/Q2377BWD
University of Pavia Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553884 (CHEMBL4787577) Show SMILES COc1ccc(cc1)C(=O)N\N=C\c1ccc(O)c(F)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Collagenase ColH (Hathewaya histolytica)	BDBM50589971 (CHEMBL5187038) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50095995 (7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...) Show SMILES CCOC(=O)c1cc2ccc(O)cc2oc1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50553879 (CHEMBL4776234) Show SMILES Oc1ccc2cc(-c3ccccc3Cl)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair
Collagenase ColG (Clostridium histolyticum)	BDBM50589972 (CHEMBL5191074) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair
Collagenase ColG (Clostridium histolyticum)	BDBM50589971 (CHEMBL5187038) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00785 BindingDB Entry DOI: 10.7270/Q2HD80NZ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186426 (CHEMBL210858 \| US10336721, ISO-1 \| US10968198, ISO...) Show SMILES COC(=O)CC1CC(=NO1)c1ccc(O)cc1 \|c:7\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01160 BindingDB Entry DOI: 10.7270/Q2KW5KPR
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)

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