Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50064015![]() (7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibitory activity against L-arginine binding to Inducible nitric oxide synthase | J Med Chem 41: 1361-6 (1998) Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453625![]() (CHEMBL2110229) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453625![]() (CHEMBL2110229) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453616![]() (CHEMBL2110337) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036790![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036790![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036806![]() (2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453616![]() (CHEMBL2110337) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453625![]() (CHEMBL2110229) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453625![]() (CHEMBL2110229) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036793![]() (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036805![]() (4-(4-{2-Amino-2-[(R)-1-(3-phenyl-propylcarbamoyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036793![]() (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036802![]() ((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036802![]() ((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036797![]() (2-Amino-3-[4-(4-cyano-benzyloxy)-2,6-dimethyl-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 28.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453629![]() (CHEMBL170594) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453628![]() (CHEMBL2110227) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453616![]() (CHEMBL2110337) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453629![]() (CHEMBL170594) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50062142![]() (4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Neuronal nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036790![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50062142![]() (4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Inducible nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50062133![]() (4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Inducible nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036790![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036806![]() (2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453616![]() (CHEMBL2110337) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50104649![]() (7-(2-Nitro-ethyl)-azepan-(2Z)-ylideneamine | CHEMB...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Curated by ChEMBL | Assay Description Inhibition of inducible nitric oxide synthase | Bioorg Med Chem Lett 11: 2651-3 (2001) BindingDB Entry DOI: 10.7270/Q24T6HPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50064015![]() (7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... | J Med Chem 41: 1361-6 (1998) Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50066778![]() (5-Ethyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50066778![]() (5-Ethyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hyd...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50064018![]() (7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... | J Med Chem 41: 1361-6 (1998) Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50062133![]() (4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Neuronal nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50062132![]() (6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Inducible nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036787![]() (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 221 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50066775![]() (5-Pentyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50066785![]() (4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM50062142![]() (4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS) | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50453625![]() (CHEMBL2110229) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50104649![]() (7-(2-Nitro-ethyl)-azepan-(2Z)-ylideneamine | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 339 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Curated by ChEMBL | Assay Description Inhibition of Neuronal nitric oxide synthase | Bioorg Med Chem Lett 11: 2651-3 (2001) BindingDB Entry DOI: 10.7270/Q24T6HPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50066774![]() (4-Methyl-5-pentyl-pyrrolidin-(2E)-ylideneamine; hy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM50066774![]() (4-Methyl-5-pentyl-pyrrolidin-(2E)-ylideneamine; hy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036793![]() (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 367 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50036793![]() (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 367 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Curated by ChEMBL | Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes | J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50066785![]() (4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase | J Med Chem 41: 3675-83 (1998) Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM50062137![]() (6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development Curated by ChEMBL | Assay Description Inhibition of human Neuronal nitric oxide synthase | J Med Chem 41: 96-101 (1998) Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 | |||||||||||
More data for this Ligand-Target Pair |
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