Compile Data Set for Download or QSAR

Found 125 hits with Last Name = 'george' and Initial = 'cf'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined as ability to displace [3H]-U-69, radioligand from Opioid receptor kappa 1				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50039026 (4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(O)c1 Show InChI InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding in Guinea pig Caudate stimulated by the opioid receptor agonist Mu-DAMGO				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined as ability to displace [3H]-DAMGO radioligand from Mu opioid receptor				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C21H27NO/c1-17-16-22(13-11-18-7-4-3-5-8-18)14-12-21(17,2)19-9-6-10-20(23)15-19/h3-10,15,17,23H,11-14,16H2,1-2H3/t17-,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Mu opioid receptor using [3H]-Naltrexone as radioligand				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C21H27NO/c1-17-16-22(13-11-18-7-4-3-5-8-18)14-12-21(17,2)19-9-6-10-20(23)15-19/h3-10,15,17,23H,11-14,16H2,1-2H3/t17-,21+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]-Naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50039029 ((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r| Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098462 (4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-hydroxy-ph...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(O)c1 Show InChI InChI=1S/C26H35N3O2/c1-5-16-27-17-15-25(20(4)19-27)29(23-9-8-10-24(30)18-23)22-13-11-21(12-14-22)26(31)28(6-2)7-3/h5,8-14,18,20,25,30H,1,6-7,15-17,19H2,2-4H3/t20-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by U69,593 in Opioid receptor kappa 1				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Mu opioid receptor using [3H]naltrexone as radioligand				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in rat brain membranes.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 using [3H]ethylketocyclazocine as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Opioid receptor kappa 1 using [3H]-Ethylketocyclazocine as radioligand				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against Opioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding to Opioid receptor kappa 1				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083637 (4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083637 (4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50072452 (3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10...) Show SMILES C[C@@]12CN(CCc3ccccc3)CC[C@@]1(Cc1ccccc1C2)c1cccc(O)c1 Show InChI InChI=1S/C28H31NO/c1-27-19-23-10-5-6-11-24(23)20-28(27,25-12-7-13-26(30)18-25)15-17-29(21-27)16-14-22-8-3-2-4-9-22/h2-13,18,30H,14-17,19-21H2,1H3/t27-,28-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding Opioid receptor kappa 1				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50072452 (3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10...) Show SMILES C[C@@]12CN(CCc3ccccc3)CC[C@@]1(Cc1ccccc1C2)c1cccc(O)c1 Show InChI InChI=1S/C28H31NO/c1-27-19-23-10-5-6-11-24(23)20-28(27,25-12-7-13-26(30)18-25)15-17-29(21-27)16-14-22-8-3-2-4-9-22/h2-13,18,30H,14-17,19-21H2,1H3/t27-,28-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding to Opioid receptor kappa 1				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50072452 (3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10...) Show SMILES C[C@@]12CN(CCc3ccccc3)CC[C@@]1(Cc1ccccc1C2)c1cccc(O)c1 Show InChI InChI=1S/C28H31NO/c1-27-19-23-10-5-6-11-24(23)20-28(27,25-12-7-13-26(30)18-25)15-17-29(21-27)16-14-22-8-3-2-4-9-22/h2-13,18,30H,14-17,19-21H2,1H3/t27-,28-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding in Guinea pig Caudate stimulated by the opioid receptor agonist Mu-DAMGO				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50072452 (3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10...) Show SMILES C[C@@]12CN(CCc3ccccc3)CC[C@@]1(Cc1ccccc1C2)c1cccc(O)c1 Show InChI InChI=1S/C28H31NO/c1-27-19-23-10-5-6-11-24(23)20-28(27,25-12-7-13-26(30)18-25)15-17-29(21-27)16-14-22-8-3-2-4-9-22/h2-13,18,30H,14-17,19-21H2,1H3/t27-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined as ability to displace [3H]-DAMGO radioligand from Mu opioid receptor				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083637 (4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50067447 (3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]no...) Show SMILES C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding activity against kOpioid receptor kappa 1 using [3H]U69,593 as radioligand in guinea pig membranes .				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098465 (CHEMBL353745 | N,N-Diethyl-4-{[3-methyl-1-(3-methy...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1ccccc1 Show InChI InChI=1S/C28H39N3O/c1-6-30(7-2)28(32)24-13-15-26(16-14-24)31(25-11-9-8-10-12-25)27-18-20-29(21-23(27)5)19-17-22(3)4/h8-17,23,27H,6-7,18-21H2,1-5H3/t23-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098446 (4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	18.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by SNC80 (Opioid receptor delta 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [35S]-GTP-gammaS, binding in Guinea pig Caudate stimulated by the Opioid receptor delta 1 agonist Delta-SNC...				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098451 (4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50067446 (3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-...) Show SMILES C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 Show InChI InChI=1S/C16H23NO/c1-12-15-7-4-8-16(12,9-10-17(15)2)13-5-3-6-14(18)11-13/h3,5-6,11-12,15,18H,4,7-10H2,1-2H3/t12-,15?,16?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]-GTP-gammaS, binding in guinea pig caudate stimulated by DAMGO (Opioid receptor mu 1)				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098447 (4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(OC)c1 Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098468 (CHEMBL176806 | N,N-Diethyl-4-{[3-methyl-1-(2-methy...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C27H37N3O/c1-6-29(7-2)27(31)23-13-15-25(16-14-23)30(24-11-9-8-10-12-24)26-17-18-28(19-21(3)4)20-22(26)5/h8-16,22,26H,3,6-7,17-20H2,1-2,4-5H3/t22-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098458 (CHEMBL177610 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1cccc(-[#8]-[#6])c1 Show InChI InChI=1S/C29H41N3O2/c1-7-31(8-2)29(33)24-12-14-25(15-13-24)32(26-10-9-11-27(20-26)34-6)28-17-19-30(21-23(28)5)18-16-22(3)4/h9-16,20,23,28H,7-8,17-19,21H2,1-6H3/t23-,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50039026 (4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(O)c1 Show InChI InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [3H]DAMGO to the mu opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098455 (4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1cccc(OC)c1 Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098457 (4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C21H27NO/c1-17-16-22(13-11-18-7-4-3-5-8-18)14-12-21(17,2)19-9-6-10-20(23)15-19/h3-10,15,17,23H,11-14,16H2,1-2H3/t17-,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Opioid receptor kappa 1 using [3H]-Ethylketocyclazocine as radioligand				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50045767 ((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...) Show SMILES C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C21H27NO/c1-17-16-22(13-11-18-7-4-3-5-8-18)14-12-21(17,2)19-9-6-10-20(23)15-19/h3-10,15,17,23H,11-14,16H2,1-2H3/t17-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 using [3H]-Ethylketocyclazocine as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098446 (4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50072453 (3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahy...) Show SMILES CN1CC[C@@]2(Cc3ccccc3C[C@]2(C)C1)c1cccc(O)c1 Show InChI InChI=1S/C21H25NO/c1-20-13-16-6-3-4-7-17(16)14-21(20,10-11-22(2)15-20)18-8-5-9-19(23)12-18/h3-9,12,23H,10-11,13-15H2,1-2H3/t20-,21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined as ability to displace [3H]-U-69, radioligand from Opioid receptor kappa 1				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098466 (CHEMBL175511 | N,N-Diethyl-4-{[3-methyl-1-(3-pheny...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1ccccc1 Show InChI InChI=1S/C32H39N3O/c1-4-34(5-2)32(36)28-18-20-30(21-19-28)35(29-16-10-7-11-17-29)31-22-24-33(25-26(31)3)23-12-15-27-13-8-6-9-14-27/h6-21,26,31H,4-5,22-25H2,1-3H3/b15-12+/t26-,31+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50098459 (CHEMBL434685 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1cccc(OC)c1 Show InChI InChI=1S/C28H39N3O2/c1-7-30(8-2)28(32)23-12-14-24(15-13-23)31(25-10-9-11-26(18-25)33-6)27-16-17-29(19-21(3)4)20-22(27)5/h9-15,18,22,27H,3,7-8,16-17,19-20H2,1-2,4-6H3/t22-,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [H]DADLE to the delta opioid receptor from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50098462 (4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-hydroxy-ph...) Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(O)c1 Show InChI InChI=1S/C26H35N3O2/c1-5-16-27-17-15-25(20(4)19-27)29(23-9-8-10-24(30)18-23)22-13-11-21(12-14-22)26(31)28(6-2)7-3/h5,8-14,18,20,25,30H,1,6-7,15-17,19H2,2-4H3/t20-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	76.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain				J Med Chem 44: 972-87 (2001) BindingDB Entry DOI: 10.7270/Q2V69K8G
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50045772 (3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol ...) Show SMILES C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11-10-15(3)8-7-14(11,2)12-5-4-6-13(16)9-12/h4-6,9,11,16H,7-8,10H2,1-3H3/t11-,14+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was determined against Mu opioid receptor using [3H]-Naltrexone as radioligand				Bioorg Med Chem Lett 8: 3149-52 (1999) BindingDB Entry DOI: 10.7270/Q2S75FGQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50045772 (3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol ...) Show SMILES C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11-10-15(3)8-7-14(11,2)12-5-4-6-13(16)9-12/h4-6,9,11,16H,7-8,10H2,1-3H3/t11-,14+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 using [3H]-Naloxone as radioligand.				J Med Chem 41: 4143-9 (1998) Article DOI: 10.1021/jm980290i BindingDB Entry DOI: 10.7270/Q2RB73Q6
					More data for this Ligand-Target Pair

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