Compile Data Set for Download or QSAR

Found 178 hits with Last Name = 'finkin-groner' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607682 (CHEMBL5220685) Show SMILES COC(=O)[C@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607676 (CHEMBL5218698) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607678 (CHEMBL5218878) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCNC(=O)C1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607686 (CHEMBL5219830) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607673 (CHEMBL5220895) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3CC(C2)O3)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607674 (CHEMBL5220347) Show SMILES Cn1cc(Cc2ccccc2OCCN2CC3(COC3)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM50400030 (CHEMBL2177713) Show SMILES CCN(C)C(=O)Oc1cccc2C(CCC(=O)OC)CNc12 Show InChI InChI=1S/C16H22N2O4/c1-4-18(2)16(20)22-13-7-5-6-12-11(10-17-15(12)13)8-9-14(19)21-3/h5-7,11,17H,4,8-10H2,1-3H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of equine BuChE after 120 mins by Ellman's method				J Med Chem 55: 10700-15 (2012) Article DOI: 10.1021/jm301411g BindingDB Entry DOI: 10.7270/Q23X87S3
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607685 (CHEMBL5220647) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCOC[C@@H]1CO)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607672 (CHEMBL5220723) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCOCC2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607679 (CHEMBL5218615) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCS(=O)(=O)CC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607675 (CHEMBL5219922) Show SMILES Cn1cc(Cc2ccccc2OCCN2CCNC(=O)C2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607680 (CHEMBL5218702) Show SMILES CC1(O)CCN(CCOc2ccccc2Cc2cn(nc2-c2cc(Cl)nc(N)n2)C(F)F)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607681 (CHEMBL5218552) Show SMILES COC(=O)[C@@H]1COCCN1CCOc1ccccc1Cc1cn(nc1-c1cc(Cl)nc(N)n1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607667 (CHEMBL5219530) Show SMILES COC(=O)c1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607684 (CHEMBL5219443) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577248 (CHEMBL4878379) Show SMILES COC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607683 (CHEMBL5219579) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCCN1CCO[C@@H](CO)C1)C(F)F |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Rattus norvegicus)	BDBM50607677 (CHEMBL5220632) Show SMILES Nc1nc(Cl)cc(n1)-c1nn(cc1Cc1ccccc1OCC(=O)N1CCOCC1)C(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Parkinson disease protein 7 (Homo sapiens)	BDBM50597609 (CHEMBL5202724) Show SMILES COc1cc(F)cc2C(=O)C(=O)N(CCc3ccccc3)c12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair
Parkinson disease protein 7 (Homo sapiens)	BDBM50597599 (CHEMBL406190) Show SMILES Brc1cc2C(=O)C(=O)N(CCc3ccccc3)c2c(Br)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607660 (CHEMBL5221008) Show SMILES Cn1cc(Cc2ccccc2Cl)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607666 (CHEMBL5220075) Show SMILES COc1ccccc1Cc1cn(C)nc1-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Parkinson disease protein 7 (Homo sapiens)	BDBM50597613 (CHEMBL5192433) Show SMILES Fc1ccc2N(CCc3ccccc3)C(=O)C(Cl)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607671 (CHEMBL5221093) Show SMILES Cn1cc(Cc2ccccc2Oc2ccccc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577243 (CHEMBL4868801) Show SMILES Cc1c(Cc2cccc(Cl)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50607662 (CHEMBL5219193) Show SMILES Nc1nc(Cl)cc(n1)-c1nn2ccccc2c1Cc1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair
Parkinson disease protein 7 (Homo sapiens)	BDBM50597603 (CHEMBL5176828) Show SMILES CCN1C(=O)C(=O)c2cc(F)ccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair
Parkinson disease protein 7 (Homo sapiens)	BDBM50597598 (CHEMBL5172713) Show SMILES Fc1ccc2N(CCc3ccccc3)C(=O)C(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577244 (CHEMBL4864668) Show SMILES Cc1c(Cc2cccc(F)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577236 (CHEMBL4857305) Show SMILES Cn1cc(Cc2ccccc2F)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577232 (CHEMBL4849033) Show SMILES Cn1cc(Cc2cccs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) Show SMILES [H][C@@](C)(N(C)C)c1cccc(OC(=O)N(C)CC)c1 Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bar Ilan University Curated by ChEMBL					Assay Description Inhibition of equine BuChE after 120 mins by Ellman's method				J Med Chem 55: 10700-15 (2012) Article DOI: 10.1021/jm301411g BindingDB Entry DOI: 10.7270/Q23X87S3
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01133 BindingDB Entry DOI: 10.7270/Q2057M2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Parkinson disease protein 7 (Homo sapiens)	BDBM50597611 (CHEMBL5205386) Show SMILES O=C1C=C(CCc2ccccc2)c2ccccc2C1=O |t:2| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00062d BindingDB Entry DOI: 10.7270/Q2RV0SRF
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)

Displayed 1 to 50 (of 178 total )  |  Next  |  Last  >>

Jump to: