BindingDB PrimarySearch

Found 137 hits with Last Name = 'hussain' and Initial = 'f'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome c oxidase subunit 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193713 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3n) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193706 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3g) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193709 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3j) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193717 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3r) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189387 (3-((1-(2-chlorophenyl)-1H-1,2,3-triazol-4-yl)methy...) Show SMILES Clc1ccccc1-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193701 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3b) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189384 (3-((1-(pyridin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)...) Show SMILES O=c1oc2cccnc2n1Cc1cn(nn1)-c1cccnc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome c oxidase subunit 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193703 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3d) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189386 (3-((1-(2-bromophenyl)-1H-1,2,3-triazol-4-yl)methyl...) Show SMILES Brc1ccccc1-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189389 (3-((1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl)methy...) Show SMILES Fc1ccccc1-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193702 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3c) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	437	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM13066 (2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...) Show SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mins by UV-v...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193710 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3k) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193712 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3m) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	577	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193716 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3q) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	587	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea \|...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189394 (3-((1-o-tolyl-1H-1,2,3-triazol-4-yl)methyl)oxazolo...) Show SMILES Cc1ccccc1-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189397 (3-((1-(2-methoxyphenyl)-1H-1,2,3-triazol-4-yl)meth...) Show SMILES COc1ccccc1-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193700 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3a) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	744	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50558938 (CHEMBL4797337) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50558934 (CHEMBL4754218) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human 5LOX expressed in baculovirus infected Sf insect cells using linoleic acid as substrate preincubated for 5 mins follo...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193704 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3e) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	916	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Cytochrome c oxidase subunit 2 (Homo sapiens (Human))	BDBM50558934 (CHEMBL4754218) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193714 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3o) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193708 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3i) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193705 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3f) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193707 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3h) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193715 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3p) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM193711 (Pyrimidin-4-one-1,2,3-triazole conjugate, 3l) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolved in dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...				Bioorg Chem 68: 41-55 (2016) Article DOI: 10.1016/j.bioorg.2016.07.007 BindingDB Entry DOI: 10.7270/Q2WM1C6H
Jamia Hamdard (Hamdard University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016433 (CHEMBL3264693) Show SMILES Clc1ccc(cc1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome c oxidase subunit 2 (Homo sapiens (Human))	BDBM50558936 (CHEMBL4794507) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016431 (CHEMBL3264691) Show SMILES COc1ccc(cc1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016401 (CHEMBL3264699) Show SMILES Fc1ccccc1-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM189385 (3-((1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl)methy...) Show SMILES Fc1ccc(cc1)-n1cc(Cn2c3ncccc3oc2=O)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	30
Hamdard University (Jamia Hamdard)					Assay Description In a typical assay, 10 �L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 �...				Chem Biol Drug Des 87: 918-26 (2016) Article DOI: 10.1111/cbdd.12724 BindingDB Entry DOI: 10.7270/Q28914NR
Hamdard University (Jamia Hamdard)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016438 (CHEMBL3264698) Show SMILES Brc1ccccc1-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016435 (CHEMBL3264695) Show SMILES Brc1ccc(cc1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016428 (CHEMBL3264702) Show SMILES CCOc1ccc(cc1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016434 (CHEMBL3264694) Show SMILES Clc1ccccc1-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016442 (CHEMBL3264690) Show SMILES CCc1ccc(cc1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016427 (CHEMBL3264701) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016429 (CHEMBL3264703) Show SMILES C(Sc1nc2ccccc2o1)c1cn(nn1)-c1cccnc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome c oxidase subunit 2 (Homo sapiens (Human))	BDBM50558937 (CHEMBL4779865) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human COX2 expressed in baculovirus infected Sf21 cells using arachidonic acid as substrate preincubated for 5 mins followe...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111863 BindingDB Entry DOI: 10.7270/Q27S7SFQ
TBA					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016419 (CHEMBL3264700) Show SMILES Cc1ccc(cc1C)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50016432 (CHEMBL3264692) Show SMILES Clc1cccc(c1)-n1cc(CSc2nc3ccccc3o2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of COX-2 (unknown origin)				Eur J Med Chem 81: 204-17 (2014) Article DOI: 10.1016/j.ejmech.2014.05.012 BindingDB Entry DOI: 10.7270/Q2GM88VQ
Jamia Hamdard (Hamdard University) Curated by ChEMBL					More data for this Ligand-Target Pair

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