Compile Data Set for Download or QSAR

Found 227 hits with Last Name = 'sanz' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270852 (CHEMBL4125770) Show SMILES Cl.NC(=N)Nc1cc2CCCCc2s1 Show InChI InChI=1S/C9H13N3S/c10-9(11)12-8-5-6-3-1-2-4-7(6)13-8/h5H,1-4H2,(H4,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270853 (CHEMBL4128374) Show SMILES Cl.NC(=N)Nc1cc2CCCc2s1 Show InChI InChI=1S/C8H11N3S/c9-8(10)11-7-4-5-2-1-3-6(5)12-7/h4H,1-3H2,(H4,9,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270851 (CHEMBL4127137) Show SMILES Cl.NC(=N)Nc1cc2CCCCCc2s1 Show InChI InChI=1S/C10H15N3S/c11-10(12)13-9-6-7-4-2-1-3-5-8(7)14-9/h6H,1-5H2,(H4,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270781 (CHEMBL4129213) Show SMILES Cl.NC(=N)Nc1nc2CCCc2s1 Show InChI InChI=1S/C7H10N4S/c8-6(9)11-7-10-4-2-1-3-5(4)12-7/h1-3H2,(H4,8,9,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	706	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270854 (CHEMBL4127933) Show SMILES Cl.NC(=N)Nc1sc2CCCCc2c1C#N Show InChI InChI=1S/C10H12N4S/c11-5-7-6-3-1-2-4-8(6)15-9(7)14-10(12)13/h1-4H2,(H4,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	733	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270855 (CHEMBL4129427) Show SMILES Cl.NC(=N)NCCc1cccs1 Show InChI InChI=1S/C7H11N3S/c8-7(9)10-4-3-6-2-1-5-11-6/h1-2,5H,3-4H2,(H4,8,9,10)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	751	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270857 (CHEMBL4126539) Show SMILES Cl.NC(=N)Nc1sc2CCCCCc2c1C#N Show InChI InChI=1S/C11H14N4S/c12-6-8-7-4-2-1-3-5-9(7)16-10(8)15-11(13)14/h1-5H2,(H4,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270780 (CHEMBL4125903) Show SMILES Cl.NC(=N)Nc1nc2CCCCc2s1 Show InChI InChI=1S/C8H12N4S/c9-7(10)12-8-11-5-3-1-2-4-6(5)13-8/h1-4H2,(H4,9,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270856 (CHEMBL4127002) Show SMILES Cl.NC(=N)Nc1ccsc1 Show InChI InChI=1S/C5H7N3S/c6-5(7)8-4-1-2-9-3-4/h1-3H,(H4,6,7,8)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270858 (CHEMBL4130226) Show SMILES Cl.NC(=N)Nc1sc2CCCc2c1C#N Show InChI InChI=1S/C9H10N4S/c10-4-6-5-2-1-3-7(5)14-8(6)13-9(11)12/h1-3H2,(H4,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50013046 (1-(Thiophen-2-ylmethyl)guanidine | CHEMBL93064 | N...) Show SMILES NC(=N)NCc1cccs1 Show InChI InChI=1S/C6H9N3S/c7-6(8)9-4-5-2-1-3-10-5/h1-3H,4H2,(H4,7,8,9)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270866 (CHEMBL4125729) Show SMILES Cl.CCOC(=O)c1c(NC(N)=N)sc2CCCCc12 Show InChI InChI=1S/C12H17N3O2S/c1-2-17-11(16)9-7-5-3-4-6-8(7)18-10(9)15-12(13)14/h2-6H2,1H3,(H4,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270867 (CHEMBL4128049) Show SMILES Cl.CCOC(=O)c1c(NC(N)=N)sc2CCCc12 Show InChI InChI=1S/C11H15N3O2S/c1-2-16-10(15)8-6-4-3-5-7(6)17-9(8)14-11(12)13/h2-5H2,1H3,(H4,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270859 (CHEMBL4126954) Show SMILES Cl.CCOC(=O)c1c(C)csc1NC(N)=N Show InChI InChI=1S/C9H13N3O2S/c1-3-14-8(13)6-5(2)4-15-7(6)12-9(10)11/h4H,3H2,1-2H3,(H4,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.65E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270865 (CHEMBL4129015) Show SMILES Cl.CCOC(=O)c1c(NC(N)=N)sc2CCCCCc12 Show InChI InChI=1S/C13H19N3O2S/c1-2-18-12(17)10-8-6-4-3-5-7-9(8)19-11(10)16-13(14)15/h2-7H2,1H3,(H4,14,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270869 (CHEMBL4128195) Show SMILES Cl.COC(=O)c1ccsc1NC(N)=N Show InChI InChI=1S/C7H9N3O2S/c1-12-6(11)4-2-3-13-5(4)10-7(8)9/h2-3H,1H3,(H4,8,9,10)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50270868 (CHEMBL4127048) Show SMILES Cl.COC(=O)c1sccc1NC(N)=N Show InChI InChI=1S/C7H9N3O2S/c1-12-6(11)5-4(2-3-13-5)10-7(8)9/h2-3H,1H3,(H4,8,9,10)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2 adrenergic receptor in human brain prefrontal cortex membranes after 30 mins by microbeta liquid scintillati...				Eur J Med Chem 138: 38-50 (2017) Article DOI: 10.1016/j.ejmech.2017.06.008 BindingDB Entry DOI: 10.7270/Q2BV7K3C
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437233 (CHEMBL2402911) Show SMILES CC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C21H23NO4/c1-14(23)15-6-5-7-16(12-15)19-13-18(10-11-20(19)24)26-21(25)22-17-8-3-2-4-9-17/h5-7,10-13,17,24H,2-4,8-9H2,1H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Apolipoprotein(a) (Human)	BDBM544456 ((2S)-3-[3-[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-3-...) Show SMILES OC(=O)[C@@H](Cc1cccc(Nc2cccc(C[C@@H]([C@H]3CCNC3)C(O)=O)c2)c1)C1CCNC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.314	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...				Citation and Details BindingDB Entry DOI: 10.7270/Q21N84BN
					More data for this Ligand-Target Pair
Apolipoprotein(a) (Human)	BDBM544455 (3-[3-[[bis[[3-[2-carboxy-2-[(3R)-pyrrolidin-3-yl]p...) Show SMILES CC(Cc1cccc(CN(Cc2cccc(CC(C)([C@H]3CCNC3)C(O)=O)c2)Cc2cccc(CC(C)([C@H]3CCNC3)C(O)=O)c2)c1)(C1CCNC1)C(O)=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.314	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...				Citation and Details BindingDB Entry DOI: 10.7270/Q21N84BN
					More data for this Ligand-Target Pair
Apolipoprotein(a) (Human)	BDBM544449 ((2S)-3-[3-[[Bis[[3-[(2S)-2-carboxy-2-[(3R)-pyrroli...) Show SMILES OC(=O)[C@@H](Cc1cccc(CN(Cc2cccc(C[C@@H]([C@H]3CCNC3)C(O)=O)c2)Cc2cccc(C[C@@H]([C@H]3CCNC3)C(O)=O)c2)c1)C1CCNC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.314	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...				Citation and Details BindingDB Entry DOI: 10.7270/Q21N84BN
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437232 (3‐(3‐carbamoylphenyl)‐4‐me...) Show SMILES COc1ccc(OC(=O)NC2CCCCC2)cc1-c1cccc(c1)C(N)=O Show InChI InChI=1S/C21H24N2O4/c1-26-19-11-10-17(27-21(25)23-16-8-3-2-4-9-16)13-18(19)14-6-5-7-15(12-14)20(22)24/h5-7,10-13,16H,2-4,8-9H2,1H3,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437231 (CHEMBL2402925) Show SMILES NC(=O)c1cccc(c1)-c1cc(O)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H22N2O4/c21-19(24)14-6-4-5-13(9-14)15-10-17(23)12-18(11-15)26-20(25)22-16-7-2-1-3-8-16/h4-6,9-12,16,23H,1-3,7-8H2,(H2,21,24)(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM14434 (6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl...) Show SMILES Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1 Show InChI InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.860	n/a	n/a	n/a	n/a	7.5	22
Janssen Research Foundation					Assay Description Compounds were tested as inhibitors of FTase in vitro using purified human enzyme to catalyze the reaction between [3H] FPP and a biotinylated peptid...				Cancer Res 61: 131-7 (2001) BindingDB Entry DOI: 10.7270/Q20C4T2R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437230 (CHEMBL2402922) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1CO Show InChI InChI=1S/C21H24N2O4/c22-20(25)15-6-4-5-14(11-15)19-12-18(10-9-16(19)13-24)27-21(26)23-17-7-2-1-3-8-17/h4-6,9-12,17,24H,1-3,7-8,13H2,(H2,22,25)(H,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437229 (CHEMBL2402915) Show SMILES CN(C)C(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C22H26N2O4/c1-24(2)21(26)16-8-6-7-15(13-16)19-14-18(11-12-20(19)25)28-22(27)23-17-9-4-3-5-10-17/h6-8,11-14,17,25H,3-5,9-10H2,1-2H3,(H,23,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437228 (CHEMBL2402920) Show SMILES OCc1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C20H23NO4/c22-13-14-5-4-6-15(11-14)18-12-17(9-10-19(18)23)25-20(24)21-16-7-2-1-3-8-16/h4-6,9-12,16,22-23H,1-3,7-8,13H2,(H,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437225 (CHEMBL2402926) Show SMILES COc1cc(OC(=O)NC2CCCCC2)cc(c1)-c1cccc(c1)C(N)=O Show InChI InChI=1S/C21H24N2O4/c1-26-18-11-16(14-6-5-7-15(10-14)20(22)24)12-19(13-18)27-21(25)23-17-8-3-2-4-9-17/h5-7,10-13,17H,2-4,8-9H2,1H3,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437226 (CHEMBL2402919) Show SMILES CC(O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C21H25NO4/c1-14(23)15-6-5-7-16(12-15)19-13-18(10-11-20(19)24)26-21(25)22-17-8-3-2-4-9-17/h5-7,10-14,17,23-24H,2-4,8-9H2,1H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437227 (CHEMBL2402927 | US9187413, 1b (URB937)) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C20H22N2O4/c21-19(24)14-6-4-5-13(11-14)17-12-16(9-10-18(17)23)26-20(25)22-15-7-2-1-3-8-15/h4-6,9-12,15,23H,1-3,7-8H2,(H2,21,24)(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Apolipoprotein(a) (Human)	BDBM544454 ((2S)-3-[3-[[[3-[(2S)-2-Carboxy-2-[(3R)-pyrrolidin-...) Show SMILES OC(=O)[C@@H](Cc1cccc(CNCc2cccc(C[C@@H]([C@H]3CCNC3)C(O)=O)c2)c1)C1CCNC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The in vitro binding affinity of compounds to the intended target human Apo(a) protein is tested in a competitive binding assay. Human Apo(a) protein...				Citation and Details BindingDB Entry DOI: 10.7270/Q21N84BN
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437224 (CHEMBL2402918) Show SMILES Cc1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C20H23NO3/c1-14-6-5-7-15(12-14)18-13-17(10-11-19(18)22)24-20(23)21-16-8-3-2-4-9-16/h5-7,10-13,16,22H,2-4,8-9H2,1H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437223 (CHEMBL2402916) Show SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C19H22N2O5S/c20-27(24,25)16-8-4-5-13(11-16)17-12-15(9-10-18(17)22)26-19(23)21-14-6-2-1-3-7-14/h4-5,8-12,14,22H,1-3,6-7H2,(H,21,23)(H2,20,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585211 (US11530193, Example 127) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C1CCN(CC1)C(C)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585168 (US11530193, Example 79) Show SMILES CC(C)n1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(-c2ccc(cc2)C(F)(F)F)c1=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585207 (US11530193, Example 123) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C1CCOCC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM50250527 (CHEMBL4066837) Show SMILES Cl.[H][C@@]1(CCCN1)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N[C@@H](C)CC)nc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C24H34N4O4S.ClH/c1-4-16(2)26-21-14-18(15-22(28-21)33(3,31)32)24(30)27-20(13-17-9-6-5-7-10-17)23(29)19-11-8-12-25-19;/h5-7,9-10,14-16,19-20,23,25,29H,4,8,11-13H2,1-3H3,(H,26,28)(H,27,30);1H/t16-,19+,20-,23+;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Inhibition of Fc-fused BACE1 (1 to 460 residues) (unknown origin) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by fluore...				J Med Chem 60: 9807-9820 (2017) Article DOI: 10.1021/acs.jmedchem.7b01304 BindingDB Entry DOI: 10.7270/Q29S1TGX
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585210 (US11530193, Example 126) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C1CCNCC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585159 (US11530193, Example 70) Show SMILES CC1(C)C(=O)Nc2c1cc(Nc1nc(ncc1C(N)=O)N1CCC[C@H](N)C1)cc2-c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437222 (CHEMBL2402914) Show SMILES CNC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C21H24N2O4/c1-22-20(25)15-7-5-6-14(12-15)18-13-17(10-11-19(18)24)27-21(26)23-16-8-3-2-4-9-16/h5-7,10-13,16,24H,2-4,8-9H2,1H3,(H,22,25)(H,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585158 (US11530193, Example 69) Show SMILES CC1(C)C(=O)Nc2c1cc(Nc1nc(ncc1C(N)=O)N1CCC[C@H](N)C1)cc2C1=CCCCC1 |r,t:33| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585167 (US11530193, Example 78) Show SMILES CC(C)n1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(-c2ccc(Cl)cc2)c1=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437221 (CHEMBL2402917) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C20H23NO5S/c1-27(24,25)17-9-5-6-14(12-17)18-13-16(10-11-19(18)22)26-20(23)21-15-7-3-2-4-8-15/h5-6,9-13,15,22H,2-4,7-8H2,1H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585218 (US11530193, Example 133) Show SMILES COc1ccc(cc1)-c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(c1)C(C)(C)O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585217 (US11530193, Example 132) Show SMILES COc1ccc(cc1)-c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585172 (US11530193, Example 83) Show SMILES CC(C)n1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(C2CCC(F)(F)CC2)c1=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM26739 (3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino US Patent					Assay Description The assays for compounds described herein are amenable to high throughput screening. Preferred assays thus detect binding of the inhibitor to FAAH or...				US Patent US9187413 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VD1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM14434 (6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl...) Show SMILES Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1 Show InChI InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	7.5	22
Janssen Research Foundation					Assay Description Compounds were tested as inhibitors of FTase in vitro using purified human enzyme to catalyze the reaction between [3H] FPP and a biotinylated peptid...				Cancer Res 61: 131-7 (2001) BindingDB Entry DOI: 10.7270/Q20C4T2R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585208 (US11530193, Example 124) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C1CCS(=O)(=O)CC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1D (Homo sapiens (Human))	BDBM585216 (US11530193, Example 131) Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C1CCCCC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following describes an ADP-Glo Kinase Assay, which measures the ADP formed from a kinase reaction; the ADP generated is converted into ATP and is...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QZ2FTP
					More data for this Ligand-Target Pair

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