Found 4749 hits with Last Name = 'whitlock' and Initial = 'g' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614966
(US20230271939, Example 4)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)c3ncccc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614995
(US20230271939, Example 33)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614999
(US20230271939, Example 37)Show SMILES COc1n[nH]c2ncc(cc12)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cnc2OC)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615005
(US20230271939, Comp Ex 4 | WO2018030466, Example 5)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ccc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614985
(US20230271939, Example 23)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cn[nH]c23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614973
(US20230271939, Example 11)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3c(N)nccn23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614994
(US20230271939, Example 32)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]c(=O)[nH]c3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614968
(US20230271939, Example 6)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615000
(US20230271939, Example 38)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)c3nccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614972
(US20230271939, Example 10)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ncc(F)c(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614979
(US20230271939, Example 17)Show SMILES OCc1cc(Cl)cc(c1Cl)S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614966
(US20230271939, Example 4)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)c3ncccc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615001
(US20230271939, Comp Ex 1)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
PDB
UniChem
| PDB
US Patent
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614965
(US20230271939, Compound Example 3 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]ncc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615002
(US20230271939, Comp Ex 2 | WO2018030466, Example 1...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1cccc(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614973
(US20230271939, Example 11)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3c(N)nccn23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614964
(US20230271939, Example 2)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1Cl | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614995
(US20230271939, Example 33)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(C)c3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614984
(US20230271939, Example 22)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3nn(C)cc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614993
(US20230271939, Example 31)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnn3cccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614963
(US20230271939, Compound Example 1 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614963
(US20230271939, Compound Example 1 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614969
(US20230271939, Example 7)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnn3c(N)ccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614978
(US20230271939, Example 16)Show SMILES Nc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614971
(US20230271939, Example 9)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3ccccc3n2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614987
(US20230271939, Example 25)Show SMILES CNc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cnc2OC)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615005
(US20230271939, Comp Ex 4 | WO2018030466, Example 5)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ccc3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615001
(US20230271939, Comp Ex 1)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
PDB
UniChem
| PDB
US Patent
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50319819
(1-(2-(3-fluoro-2-methoxyphenyl)-1-phenylethyl)pipe...)Show InChI InChI=1S/C19H23FN2O/c1-23-19-16(8-5-9-17(19)20)14-18(15-6-3-2-4-7-15)22-12-10-21-11-13-22/h2-9,18,21H,10-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay |
Bioorg Med Chem Lett 20: 3788-92 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.052
BindingDB Entry DOI: 10.7270/Q2SN09X4 |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614968
(US20230271939, Example 6)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614963
(US20230271939, Compound Example 1 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614963
(US20230271939, Compound Example 1 | US20230271939,...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614983
(US20230271939, Example 21)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3[nH]ncc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614992
(US20230271939, Example 30)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3ccnn3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614971
(US20230271939, Example 9)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3ccccc3n2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614967
(US20230271939, Example 5)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3nccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614969
(US20230271939, Example 7)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnn3c(N)ccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614986
(US20230271939, Example 24)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3cnn(C)c23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614964
(US20230271939, Example 2)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc(N)nc2)c1Cl | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614990
(US20230271939, Example 28)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]c(=O)[nH]c3n2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614998
(US20230271939, Example 36)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]c(=O)n(C)c3c2)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614967
(US20230271939, Example 5)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cncc3nccnc23)c1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50310652
((S)-3-chloro-N-isobutyl-2-methyl-N-(pyrrolidin-3-y...)Show InChI InChI=1S/C16H23ClN2O/c1-11(2)10-19(13-7-8-18-9-13)16(20)14-5-4-6-15(17)12(14)3/h4-6,11,13,18H,7-10H2,1-3H3/t13-/m0/s1 | PDB
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| CHEMBL
PC cid
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UniChem
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| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation counting |
Bioorg Med Chem Lett 19: 5078-81 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.049
BindingDB Entry DOI: 10.7270/Q2JQ115V |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50310647
((S)-2,3-dichloro-N-phenyl-N-(pyrrolidin-3-yl)benza...)Show SMILES Clc1cccc(C(=O)N([C@H]2CCNC2)c2ccccc2)c1Cl |r| Show InChI InChI=1S/C17H16Cl2N2O/c18-15-8-4-7-14(16(15)19)17(22)21(13-9-10-20-11-13)12-5-2-1-3-6-12/h1-8,13,20H,9-11H2/t13-/m0/s1 | PDB
KEGG
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| CHEMBL
PC cid
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UniChem
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation counting |
Bioorg Med Chem Lett 19: 5078-81 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.049
BindingDB Entry DOI: 10.7270/Q2JQ115V |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50310662
((S)-2,4-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)Show SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1ccc(Cl)cc1Cl |r| Show InChI InChI=1S/C15H20Cl2N2O/c1-10(2)9-19(12-5-6-18-8-12)15(20)13-4-3-11(16)7-14(13)17/h3-4,7,10,12,18H,5-6,8-9H2,1-2H3/t12-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation counting |
Bioorg Med Chem Lett 19: 5078-81 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.049
BindingDB Entry DOI: 10.7270/Q2JQ115V |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM614970
(US20230271939, Example 8)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3c(N)cccn23)c1F | PDB
MMDB
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UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| US Patent
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
eIF-2-alpha kinase GCN2
(Homo sapiens (Human)) | BDBM615002
(US20230271939, Comp Ex 2 | WO2018030466, Example 1...)Show SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1cccc(C#Cc2cnc(N)nc2)c1F | PDB
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| PC cid
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UniChem
| US Patent
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc.
US Patent
| |
US Patent US10174003 (2019)
BindingDB Entry DOI: 10.7270/Q2Q244CX |
More data for this
Ligand-Target Pair | |
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