Compile Data Set for Download or QSAR

Found 51 hits with Last Name = 'winston-mcpherson' and Initial = 'gn'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535693 (CHEMBL4572783) Show SMILES Fc1ccc2[nH]c(Cc3c[nH]c4c(F)cccc34)cc2c1 Show InChI InChI=1S/C17H12F2N2/c18-12-4-5-16-10(6-12)7-13(21-16)8-11-9-20-17-14(11)2-1-3-15(17)19/h1-7,9,20-21H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 24 hrs followed by medium replenishment and measured after 24 hrs by ELISA				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535683 (CHEMBL4549362) Show SMILES Fc1ccc2[nH]c(Cc3c[nH]c4c(Cl)cccc34)cc2c1 Show InChI InChI=1S/C17H12ClFN2/c18-15-3-1-2-14-11(9-20-17(14)15)8-13-7-10-6-12(19)4-5-16(10)21-13/h1-7,9,20-21H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535686 (CHEMBL4562557) Show SMILES Fc1cccc2c(Cc3cc4ccccc4[nH]3)c[nH]c12 Show InChI InChI=1S/C17H13FN2/c18-15-6-3-5-14-12(10-19-17(14)15)9-13-8-11-4-1-2-7-16(11)20-13/h1-8,10,19-20H,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535688 (CHEMBL4585306) Show SMILES Cc1cccc2c(Cc3cc4ccccc4[nH]3)c[nH]c12 Show InChI InChI=1S/C18H16N2/c1-12-5-4-7-16-14(11-19-18(12)16)10-15-9-13-6-2-3-8-17(13)20-15/h2-9,11,19-20H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535690 (CHEMBL4528279) Show SMILES CC(C)c1c(Cc2cn(C)c3ccccc23)n(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C28H28N2O2S/c1-19(2)28-24-10-6-8-12-26(24)30(33(31,32)22-15-13-20(3)14-16-22)27(28)17-21-18-29(4)25-11-7-5-9-23(21)25/h5-16,18-19H,17H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535687 (CHEMBL4435394) Show SMILES Cc1ccc2c(Cc3cc4ccccc4[nH]3)c[nH]c2c1 Show InChI InChI=1S/C18H16N2/c1-12-6-7-16-14(11-19-18(16)8-12)10-15-9-13-4-2-3-5-17(13)20-15/h2-9,11,19-20H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535689 (CHEMBL4462933) Show SMILES Cc1c(Cc2cn(C)c3ccccc23)n(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C26H24N2O2S/c1-18-12-14-21(15-13-18)31(29,30)28-25-11-7-4-8-22(25)19(2)26(28)16-20-17-27(3)24-10-6-5-9-23(20)24/h4-15,17H,16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535685 (CHEMBL4531399) Show SMILES Cc1ccc(cc1)S(=O)(=O)n1c(Cc2cn(C)c3ccccc23)c(-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C31H26N2O2S/c1-22-16-18-25(19-17-22)36(34,35)33-29-15-9-7-13-27(29)31(23-10-4-3-5-11-23)30(33)20-24-21-32(2)28-14-8-6-12-26(24)28/h3-19,21H,20H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535691 (CHEMBL4461546) Show SMILES Cc1c(Cc2c[nH]c3c(Cl)cccc23)n(c2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C25H21ClN2O2S/c1-16-10-12-19(13-11-16)31(29,30)28-23-9-4-3-6-20(23)17(2)24(28)14-18-15-27-25-21(18)7-5-8-22(25)26/h3-13,15,27H,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535692 (CHEMBL4545753) Show SMILES Clc1cccc2c(Cc3cc4ccccc4[nH]3)c[nH]c12 Show InChI InChI=1S/C17H13ClN2/c18-15-6-3-5-14-12(10-19-17(14)15)9-13-8-11-4-1-2-7-16(11)20-13/h1-8,10,19-20H,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50535684 (CHEMBL4446521) Show SMILES Cc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H16N2/c1-12-6-7-18-16(8-12)14(11-19-18)10-15-9-13-4-2-3-5-17(13)20-15/h2-9,11,19-20H,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50049059 (CHEMBL3319503 | US10730833, Compound 10a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C17H13ClN2/c18-13-5-6-17-15(9-13)12(10-19-17)8-14-7-11-3-1-2-4-16(11)20-14/h1-7,9-10,19-20H,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibition of human PCSK9 in HepG2 cells incubated for 48 hrs by AlphaLISA assay				Bioorg Med Chem Lett 29: 2345-2348 (2019) Article DOI: 10.1016/j.bmcl.2019.06.014 BindingDB Entry DOI: 10.7270/Q25142RQ
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049062 (CHEMBL3319500 | US10730833, Compound 11c | US99696...) Show SMILES COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C19H16N2O2/c1-23-13-6-7-17-15(9-13)12(10-20-17)8-19-16(11-22)14-4-2-3-5-18(14)21-19/h2-7,9-11,20-21H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049061 (CHEMBL3319501 | US10730833, Compound 11d | US99696...) Show SMILES Cn1cc(Cc2[nH]c3ccccc3c2C=O)c2ccccc12 Show InChI InChI=1S/C19H16N2O/c1-21-11-13(14-6-3-5-9-19(14)21)10-18-16(12-22)15-7-2-4-8-17(15)20-18/h2-9,11-12,20H,10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049060 (CHEMBL3319502 | US10730833, Compound 6' | US996968...) Show SMILES C(c1cc2ccccc2[nH]1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C17H14N2/c1-3-7-16-12(5-1)9-14(19-16)10-13-11-18-17-8-4-2-6-15(13)17/h1-9,11,18-19H,10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049059 (CHEMBL3319503 | US10730833, Compound 10a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C17H13ClN2/c18-13-5-6-17-15(9-13)12(10-19-17)8-14-7-11-3-1-2-4-16(11)20-14/h1-7,9-10,19-20H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	>6.70E+3	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049058 (CHEMBL3319504 | US10730833, Compound 10c | US99696...) Show SMILES COc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H16N2O/c1-21-15-6-7-18-16(10-15)13(11-19-18)9-14-8-12-4-2-3-5-17(12)20-14/h2-8,10-11,19-20H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049057 (CHEMBL3319505 | US10730833, Compound 10d | US99696...) Show SMILES Cn1cc(Cc2cc3ccccc3[nH]2)c2ccccc12 Show InChI InChI=1S/C18H16N2/c1-20-12-14(16-7-3-5-9-18(16)20)11-15-10-13-6-2-4-8-17(13)19-15/h2-10,12,19H,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049065 (CHEMBL3319497 | US10730833, Compound 6 | US9969686...) Show SMILES O=Cc1c(Cc2c[nH]c3ccccc23)[nH]c2ccccc12 Show InChI InChI=1S/C18H14N2O/c21-11-15-14-6-2-4-8-17(14)20-18(15)9-12-10-19-16-7-3-1-5-13(12)16/h1-8,10-11,19-20H,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049064 (CHEMBL3319498 | US10730833, Compound 11a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C18H13ClN2O/c19-12-5-6-16-14(8-12)11(9-20-16)7-18-15(10-22)13-3-1-2-4-17(13)21-18/h1-6,8-10,20-21H,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049063 (CHEMBL3319499 | US10730833, Compound 11b | US99696...) Show SMILES Clc1cccc2c(Cc3[nH]c4ccccc4c3C=O)c[nH]c12 Show InChI InChI=1S/C18H13ClN2O/c19-15-6-3-5-12-11(9-20-18(12)15)8-17-14(10-22)13-4-1-2-7-16(13)21-17/h1-7,9-10,20-21H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049062 (CHEMBL3319500 | US10730833, Compound 11c | US99696...) Show SMILES COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C19H16N2O2/c1-23-13-6-7-17-15(9-13)12(10-20-17)8-19-16(11-22)14-4-2-3-5-18(14)21-19/h2-7,9-11,20-21H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049061 (CHEMBL3319501 | US10730833, Compound 11d | US99696...) Show SMILES Cn1cc(Cc2[nH]c3ccccc3c2C=O)c2ccccc12 Show InChI InChI=1S/C19H16N2O/c1-21-11-13(14-6-3-5-9-19(14)21)10-18-16(12-22)15-7-2-4-8-17(15)20-18/h2-9,11-12,20H,10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049060 (CHEMBL3319502 | US10730833, Compound 6' | US996968...) Show SMILES C(c1cc2ccccc2[nH]1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C17H14N2/c1-3-7-16-12(5-1)9-14(19-16)10-13-11-18-17-8-4-2-6-15(13)17/h1-9,11,18-19H,10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049059 (CHEMBL3319503 | US10730833, Compound 10a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C17H13ClN2/c18-13-5-6-17-15(9-13)12(10-19-17)8-14-7-11-3-1-2-4-16(11)20-14/h1-7,9-10,19-20H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	>6.70E+3	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049058 (CHEMBL3319504 | US10730833, Compound 10c | US99696...) Show SMILES COc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H16N2O/c1-21-15-6-7-18-16(10-15)13(11-19-18)9-14-8-12-4-2-3-5-17(12)20-14/h2-8,10-11,19-20H,9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049057 (CHEMBL3319505 | US10730833, Compound 10d | US99696...) Show SMILES Cn1cc(Cc2cc3ccccc3[nH]2)c2ccccc12 Show InChI InChI=1S/C18H16N2/c1-20-12-14(16-7-3-5-9-18(16)20)11-15-10-13-6-2-4-8-17(13)19-15/h2-10,12,19H,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
Wisconsin Alumni Research Foundation US Patent					Assay Description This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....				US Patent US10730833 (2020) BindingDB Entry DOI: 10.7270/Q2BK1GFK
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50541261 (CHEMBL4646273) Show SMILES Cn1c2ccccc2c2cc3[nH]c4ccccc4c3c(C=O)c12 Show InChI InChI=1S/C20H14N2O/c1-22-18-9-5-3-6-12(18)14-10-17-19(15(11-23)20(14)22)13-7-2-4-8-16(13)21-17/h2-11,21H,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126959 BindingDB Entry DOI: 10.7270/Q2WQ07B9
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50541262 (6-Formylindolo[3,2-B]Carbazole | CHEMBL472031) Show SMILES O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12 Show InChI InChI=1S/C19H12N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10,20-21H	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126959 BindingDB Entry DOI: 10.7270/Q2WQ07B9
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565588 (CHEMBL4779430) Show SMILES Fc1ccc2nc(Cc3c[nH]c4c(F)cccc34)[nH]c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	348	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565589 (CHEMBL4789986) Show SMILES Fc1ccc2nc([nH]c2c1)C(=O)c1c[nH]c2c(F)cccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565590 (CHEMBL4780905) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1c[nH]c2c(F)cccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565591 (CHEMBL4783308) Show SMILES Cn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565592 (CHEMBL4788701) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(CCN2CCOCC2)c2c(F)cccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565593 (CHEMBL4779800) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(CCCN2CCOCC2)c2c(F)cccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565594 (CHEMBL4783828) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(CCCCN2CCOCC2)c2c(F)cccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	88	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565595 (CHEMBL4785006) Show SMILES CCCCn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565596 (CHEMBL4797870) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(c2c(F)cccc12)S(=O)(=O)CCN1CCOCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.690	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049063 (CHEMBL3319499 | US10730833, Compound 11b | US99696...) Show SMILES Clc1cccc2c(Cc3[nH]c4ccccc4c3C=O)c[nH]c12 Show InChI InChI=1S/C18H13ClN2O/c19-15-6-3-5-12-11(9-20-18(12)15)8-17-14(10-22)13-4-1-2-7-16(13)21-17/h1-7,9-10,20-21H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049064 (CHEMBL3319498 | US10730833, Compound 11a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C18H13ClN2O/c19-12-5-6-16-14(8-12)11(9-20-16)7-18-15(10-22)13-3-1-2-4-17(13)21-18/h1-6,8-10,20-21H,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049065 (CHEMBL3319497 | US10730833, Compound 6 | US9969686...) Show SMILES O=Cc1c(Cc2c[nH]c3ccccc23)[nH]c2ccccc12 Show InChI InChI=1S/C18H14N2O/c21-11-15-14-6-2-4-8-17(14)20-18(15)9-12-10-19-16-7-3-1-5-13(12)16/h1-8,10-11,19-20H,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of St Andrews					Assay Description AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.				J Med Chem 52: 2673-82 (2009) BindingDB Entry DOI: 10.7270/Q2DN47DP
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049065 (CHEMBL3319497 | US10730833, Compound 6 | US9969686...) Show SMILES O=Cc1c(Cc2c[nH]c3ccccc23)[nH]c2ccccc12 Show InChI InChI=1S/C18H14N2O/c21-11-15-14-6-2-4-8-17(14)20-18(15)9-12-10-19-16-7-3-1-5-13(12)16/h1-8,10-11,19-20H,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049064 (CHEMBL3319498 | US10730833, Compound 11a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C18H13ClN2O/c19-12-5-6-16-14(8-12)11(9-20-16)7-18-15(10-22)13-3-1-2-4-17(13)21-18/h1-6,8-10,20-21H,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049063 (CHEMBL3319499 | US10730833, Compound 11b | US99696...) Show SMILES Clc1cccc2c(Cc3[nH]c4ccccc4c3C=O)c[nH]c12 Show InChI InChI=1S/C18H13ClN2O/c19-15-6-3-5-12-11(9-20-18(12)15)8-17-14(10-22)13-4-1-2-7-16(13)21-17/h1-7,9-10,20-21H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049062 (CHEMBL3319500 | US10730833, Compound 11c | US99696...) Show SMILES COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 Show InChI InChI=1S/C19H16N2O2/c1-23-13-6-7-17-15(9-13)12(10-20-17)8-19-16(11-22)14-4-2-3-5-18(14)21-19/h2-7,9-11,20-21H,8H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049061 (CHEMBL3319501 | US10730833, Compound 11d | US99696...) Show SMILES Cn1cc(Cc2[nH]c3ccccc3c2C=O)c2ccccc12 Show InChI InChI=1S/C19H16N2O/c1-21-11-13(14-6-3-5-9-19(14)21)10-18-16(12-22)15-7-2-4-8-17(15)20-18/h2-9,11-12,20H,10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049060 (CHEMBL3319502 | US10730833, Compound 6' | US996968...) Show SMILES C(c1cc2ccccc2[nH]1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C17H14N2/c1-3-7-16-12(5-1)9-14(19-16)10-13-11-18-17-8-4-2-6-15(13)17/h1-9,11,18-19H,10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049059 (CHEMBL3319503 | US10730833, Compound 10a | US99696...) Show SMILES Clc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C17H13ClN2/c18-13-5-6-17-15(9-13)12(10-19-17)8-14-7-11-3-1-2-4-16(11)20-14/h1-7,9-10,19-20H,8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.70E+3	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human))	BDBM50565597 (CHEMBL4783880) Show SMILES Cn1c(nc2ccc(F)cc12)C(=O)c1cn(c2c(F)cccc12)S(=O)(=O)CCN1CCNCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	161	n/a	n/a	n/a	n/a
TBA					Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM50049057 (CHEMBL3319505 | US10730833, Compound 10d | US99696...) Show SMILES Cn1cc(Cc2cc3ccccc3[nH]2)c2ccccc12 Show InChI InChI=1S/C18H16N2/c1-20-12-14(16-7-3-5-9-18(16)20)11-15-10-13-6-2-4-8-17(13)19-15/h2-10,12,19H,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assay				Bioorg Med Chem Lett 24: 4023-5 (2014) Article DOI: 10.1016/j.bmcl.2014.06.009 BindingDB Entry DOI: 10.7270/Q2TX3H0Q
					More data for this Ligand-Target Pair

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