Compile Data Set for Download or QSAR

Found 126 hits with Last Name = 'boblewski' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50271255 (1-[(Imidazolidin-2-yl)imino]indazole hydrochloride...) Show SMILES [#6]-1-[#6]-[#7]\[#6](-[#7]-1)=[#7]/n1ncc2ccccc12 Show InChI InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497435 (CHEMBL3343699) Show SMILES Fc1ccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c2c1 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497438 (CHEMBL3343704) Show SMILES Fc1ccc2cnn(CC3=NCCN3)c2c1 |t:9| Show InChI InChI=1S/C11H11FN4/c12-9-2-1-8-6-15-16(10(8)5-9)7-11-13-3-4-14-11/h1-2,5-6H,3-4,7H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334197 (7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...) Show SMILES Clc1cccc2c(N=C3NCCN3)[nH]nc12 |(13.68,-39.86,;13.64,-41.39,;12.29,-42.12,;12.25,-43.67,;13.56,-44.47,;14.92,-43.74,;16.37,-44.25,;17.18,-45.57,;18.71,-45.54,;19.59,-44.27,;21.07,-44.71,;21.09,-46.25,;19.64,-46.76,;17.3,-43.03,;16.43,-41.77,;14.95,-42.2,)| Show InChI InChI=1S/C10H10ClN5/c11-7-3-1-2-6-8(7)15-16-9(6)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497439 (CHEMBL3343700) Show SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12 Show InChI InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164835 (CHEMBL3800398) Show SMILES Cl.Fc1ccc2n(CC3=NCCN3)ccc2c1 |t:7| Show InChI InChI=1S/C12H12FN3.ClH/c13-10-1-2-11-9(7-10)3-6-16(11)8-12-14-4-5-15-12;/h1-3,6-7H,4-5,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497436 (CHEMBL3343703) Show SMILES Fc1ccc2n(CC3=NCCN3)ncc2c1 |t:7| Show InChI InChI=1S/C11H11FN4/c12-9-1-2-10-8(5-9)6-15-16(10)7-11-13-3-4-14-11/h1-2,5-6H,3-4,7H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50497435 (CHEMBL3343699) Show SMILES Fc1ccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c2c1 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2A adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334195 (4-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...) Show SMILES Clc1cccc2n[nH]c(N=C3NCCN3)c12 |(20.22,-2.74,;20.26,-1.21,;18.95,-.4,;18.99,1.14,;20.34,1.87,;21.66,1.07,;23.13,1.5,;24.01,.23,;23.07,-.99,;23.88,-2.31,;25.41,-2.28,;26.29,-1.01,;27.77,-1.45,;27.8,-2.99,;26.34,-3.5,;21.62,-.47,)| Show InChI InChI=1S/C10H10ClN5/c11-6-2-1-3-7-8(6)9(16-15-7)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50271255 (1-[(Imidazolidin-2-yl)imino]indazole hydrochloride...) Show SMILES [#6]-1-[#6]-[#7]\[#6](-[#7]-1)=[#7]/n1ncc2ccccc12 Show InChI InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2A adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497440 (CHEMBL3343698) Show SMILES Fc1ccc2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc2c1 Show InChI InChI=1S/C10H10FN5/c11-8-1-2-9-7(5-8)6-14-16(9)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50497439 (CHEMBL3343700) Show SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12 Show InChI InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2A adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50497435 (CHEMBL3343699) Show SMILES Fc1ccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c2c1 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2B adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50271255 (1-[(Imidazolidin-2-yl)imino]indazole hydrochloride...) Show SMILES [#6]-1-[#6]-[#7]\[#6](-[#7]-1)=[#7]/n1ncc2ccccc12 Show InChI InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2B adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164841 (CHEMBL3798191) Show SMILES Cl.Brc1cccc2ccn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C12H12BrN3.ClH/c13-10-3-1-2-9-4-7-16(12(9)10)8-11-14-5-6-15-11;/h1-4,7H,5-6,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334196 (3-[(Imidazolidin-2-yl)imino]-4-methylindazole hydr...) Show SMILES Cc1cccc2n[nH]c(N=C3NCCN3)c12 |(-5.16,-15.24,;-5.12,-13.71,;-6.43,-12.91,;-6.38,-11.36,;-5.04,-10.63,;-3.72,-11.44,;-2.24,-11.01,;-1.37,-12.27,;-2.31,-13.49,;-1.5,-14.81,;.03,-14.78,;.91,-13.51,;2.39,-13.95,;2.42,-15.49,;.97,-16,;-3.76,-12.98,)| Show InChI InChI=1S/C11H13N5/c1-7-3-2-4-8-9(7)10(16-15-8)14-11-12-5-6-13-11/h2-4H,5-6H2,1H3,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334194 (3-[(Imidazolidin-2-yl)imino]indazole hydrochloride...) Show SMILES C1CNC(N1)=Nc1[nH]nc2ccccc12 |(1.21,-.87,;1.24,-2.41,;-.21,-2.92,;-1.14,-1.7,;-.27,-.43,;-2.68,-1.73,;-3.49,-.41,;-2.55,.82,;-3.42,2.08,;-4.9,1.65,;-6.21,2.45,;-7.56,1.72,;-7.61,.18,;-6.29,-.63,;-4.93,.11,)| Show InChI InChI=1S/C10H11N5/c1-2-4-8-7(3-1)9(15-14-8)13-10-11-5-6-12-10/h1-4H,5-6H2,(H3,11,12,13,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50497439 (CHEMBL3343700) Show SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12 Show InChI InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2B adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334206 (3-[(Imidazolidin-2-yl)imino]-4-methoxyindazole hyd...) Show SMILES COc1cccc2n[nH]c(N=C3NCCN3)c12 |(13.29,-18.77,;14.63,-18.04,;14.68,-16.51,;13.36,-15.7,;13.41,-14.16,;14.76,-13.43,;16.07,-14.23,;17.55,-13.8,;18.42,-15.07,;17.48,-16.29,;18.29,-17.61,;19.83,-17.58,;20.71,-16.31,;22.18,-16.75,;22.21,-18.29,;20.76,-18.8,;16.04,-15.77,)| Show InChI InChI=1S/C11H13N5O/c1-17-8-4-2-3-7-9(8)10(16-15-7)14-11-12-5-6-13-11/h2-4H,5-6H2,1H3,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497433 (CHEMBL3343702) Show SMILES Fc1cccc2n(CC3=NCCN3)ncc12 |t:8| Show InChI InChI=1S/C11H11FN4/c12-9-2-1-3-10-8(9)6-15-16(10)7-11-13-4-5-14-11/h1-3,6H,4-5,7H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334204 (3-[(Imidazolidin-2-yl)imino]-6-methylindazole hydr...) Show SMILES Cc1ccc2c(N=C3NCCN3)[nH]nc2c1 |(-5.95,-39.45,;-4.64,-40.25,;-4.69,-41.79,;-3.37,-42.6,;-2.01,-41.86,;-.57,-42.38,;.24,-43.7,;1.78,-43.67,;2.66,-42.4,;4.13,-42.84,;4.16,-44.38,;2.71,-44.89,;.37,-41.16,;-.5,-39.9,;-1.98,-40.32,;-3.29,-39.52,)| Show InChI InChI=1S/C11H13N5/c1-7-2-3-8-9(6-7)15-16-10(8)14-11-12-4-5-13-11/h2-3,6H,4-5H2,1H3,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334203 (6-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...) Show SMILES Clc1ccc2c(N=C3NCCN3)[nH]nc2c1 |(31.19,-27.47,;32.5,-28.27,;32.46,-29.82,;33.77,-30.62,;35.13,-29.89,;36.58,-30.4,;37.39,-31.72,;38.92,-31.69,;39.8,-30.42,;41.28,-30.86,;41.3,-32.4,;39.85,-32.91,;37.51,-29.18,;36.64,-27.92,;35.17,-28.35,;33.85,-27.54,)| Show InChI InChI=1S/C10H10ClN5/c11-6-1-2-7-8(5-6)15-16-9(7)14-10-12-3-4-13-10/h1-2,5H,3-4H2,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497434 (CHEMBL3343697) Show SMILES Fc1cccc2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc12 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-3-9-7(8)6-14-16(9)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	416	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164834 (CHEMBL3798638) Show SMILES Cl.Brc1cccc2n(CC3=NCCN3)ccc12 |t:8| Show InChI InChI=1S/C12H12BrN3.ClH/c13-10-2-1-3-11-9(10)4-7-16(11)8-12-14-5-6-15-12;/h1-4,7H,5-6,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497436 (CHEMBL3343703) Show SMILES Fc1ccc2n(CC3=NCCN3)ncc2c1 |t:7| Show InChI InChI=1S/C11H11FN4/c12-9-1-2-10-8(5-9)6-15-16(10)7-11-13-3-4-14-11/h1-2,5-6H,3-4,7H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	476	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497438 (CHEMBL3343704) Show SMILES Fc1ccc2cnn(CC3=NCCN3)c2c1 |t:9| Show InChI InChI=1S/C11H11FN4/c12-9-2-1-8-6-15-16(10(8)5-9)7-11-13-3-4-14-11/h1-2,5-6H,3-4,7H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	518	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497433 (CHEMBL3343702) Show SMILES Fc1cccc2n(CC3=NCCN3)ncc12 |t:8| Show InChI InChI=1S/C11H11FN4/c12-9-2-1-3-10-8(9)6-15-16(10)7-11-13-4-5-14-11/h1-3,6H,4-5,7H2,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	535	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50497435 (CHEMBL3343699) Show SMILES Fc1ccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c2c1 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2C adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50271255 (1-[(Imidazolidin-2-yl)imino]indazole hydrochloride...) Show SMILES [#6]-1-[#6]-[#7]\[#6](-[#7]-1)=[#7]/n1ncc2ccccc12 Show InChI InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2C adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164837 (CHEMBL3800446) Show SMILES Cl.Fc1ccc2ccn(CC3=NCCN3)c2c1 |t:9| Show InChI InChI=1S/C12H12FN3.ClH/c13-10-2-1-9-3-6-16(11(9)7-10)8-12-14-4-5-15-12;/h1-3,6-7H,4-5,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	789	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497435 (CHEMBL3343699) Show SMILES Fc1ccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c2c1 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	918	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164842 (CHEMBL3798387) Show SMILES Br.Cc1cccc2ccn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C13H15N3.BrH/c1-10-3-2-4-11-5-8-16(13(10)11)9-12-14-6-7-15-12;/h2-5,8H,6-7,9H2,1H3,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50497439 (CHEMBL3343700) Show SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12 Show InChI InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RS-79948-197 from human alpha2C adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497439 (CHEMBL3343700) Show SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12 Show InChI InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497440 (CHEMBL3343698) Show SMILES Fc1ccc2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc2c1 Show InChI InChI=1S/C10H10FN5/c11-8-1-2-9-7(5-8)6-14-16(9)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50497437 (CHEMBL3343701) Show SMILES Fc1c(F)c(F)c2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc2c1F Show InChI InChI=1S/C10H7F4N5/c11-5-4-3-17-19(18-10-15-1-2-16-10)9(4)8(14)7(13)6(5)12/h3H,1-2H2,(H2,15,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497434 (CHEMBL3343697) Show SMILES Fc1cccc2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc12 Show InChI InChI=1S/C10H10FN5/c11-8-2-1-3-9-7(8)6-14-16(9)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334205 (4-Bromo-3-[(imidazolidin-2-yl)imino]indazole hydro...) Show SMILES Brc1cccc2n[nH]c(N=C3NCCN3)c12 |(7.5,-1.88,;7.54,-.35,;6.23,.46,;6.27,2,;7.62,2.73,;8.94,1.93,;10.41,2.36,;11.29,1.09,;10.35,-.13,;11.16,-1.45,;12.69,-1.42,;13.57,-.15,;15.05,-.59,;15.08,-2.13,;13.62,-2.64,;8.9,.39,)| Show InChI InChI=1S/C10H10BrN5/c11-6-2-1-3-7-8(6)9(16-15-7)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164838 (CHEMBL3797854) Show SMILES Cl.Clc1ccc2ccn(CC3=NCCN3)c2c1 |t:9| Show InChI InChI=1S/C12H12ClN3.ClH/c13-10-2-1-9-3-6-16(11(9)7-10)8-12-14-4-5-15-12;/h1-3,6-7H,4-5,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164839 (CHEMBL3797661) Show SMILES Cl.Fc1cccc2ccn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C12H12FN3.ClH/c13-10-3-1-2-9-4-7-16(12(9)10)8-11-14-5-6-15-11;/h1-4,7H,5-6,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334202 (3-[(Imidazolidin-2-ylo)imino]-5-methoxyindazole hy...) Show SMILES COc1ccc2n[nH]c(N=C3NCCN3)c2c1 |(14.75,-30.58,;16.06,-31.39,;17.41,-30.66,;17.45,-29.12,;18.8,-28.38,;20.12,-29.19,;21.59,-28.76,;22.47,-30.02,;21.53,-31.25,;22.34,-32.56,;23.87,-32.53,;24.75,-31.26,;26.22,-31.71,;26.25,-33.25,;24.8,-33.75,;20.08,-30.73,;18.72,-31.46,)| Show InChI InChI=1S/C11H13N5O/c1-17-7-2-3-9-8(6-7)10(16-15-9)14-11-12-4-5-13-11/h2-3,6H,4-5H2,1H3,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334208 (3-[(Imidazolidin-2-yl)imino]-5-methylindazole hydr...) Show SMILES Cc1ccc2n[nH]c(N=C3NCCN3)c2c1 |(-5.41,-29.94,;-4.06,-29.21,;-4.01,-27.67,;-2.67,-26.94,;-1.35,-27.74,;.13,-27.31,;1,-28.57,;.06,-29.8,;.87,-31.12,;2.4,-31.08,;3.28,-29.82,;4.76,-30.26,;4.79,-31.8,;3.34,-32.31,;-1.39,-29.28,;-2.75,-30.02,)| Show InChI InChI=1S/C11H13N5/c1-7-2-3-9-8(6-7)10(16-15-9)14-11-12-4-5-13-11/h2-3,6H,4-5H2,1H3,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164840 (CHEMBL3799780) Show SMILES Cl.Clc1cccc2ccn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C12H12ClN3.ClH/c13-10-3-1-2-9-4-7-16(12(9)10)8-11-14-5-6-15-11;/h1-4,7H,5-6,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164836 (CHEMBL3798967) Show SMILES Cl.Brc1ccc2n(CC3=NCCN3)ccc2c1 |t:7| Show InChI InChI=1S/C12H12BrN3.ClH/c13-10-1-2-11-9(7-10)3-6-16(11)8-12-14-4-5-15-12;/h1-3,6-7H,4-5,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164833 (CHEMBL3799346) Show SMILES Cl.Fc1cccc2n(CC3=NCCN3)ccc12 |t:8| Show InChI InChI=1S/C12H12FN3.ClH/c13-10-2-1-3-11-9(10)4-7-16(11)8-12-14-5-6-15-12;/h1-4,7H,5-6,8H2,(H,14,15);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50497437 (CHEMBL3343701) Show SMILES Fc1c(F)c(F)c2n(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)ncc2c1F Show InChI InChI=1S/C10H7F4N5/c11-5-4-3-17-19(18-10-15-1-2-16-10)9(4)8(14)7(13)6(5)12/h3H,1-2H2,(H2,15,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 87: 386-97 (2014) Article DOI: 10.1016/j.ejmech.2014.09.083 BindingDB Entry DOI: 10.7270/Q2MW2M45
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164845 (CHEMBL3799081) Show SMILES Br.C(Oc1cccc2ccn(CC3=NCCN3)c12)c1ccccc1 |t:11| Show InChI InChI=1S/C19H19N3O.BrH/c1-2-5-15(6-3-1)14-23-17-8-4-7-16-9-12-22(19(16)17)13-18-20-10-11-21-18;/h1-9,12H,10-11,13-14H2,(H,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164843 (CHEMBL3800486) Show SMILES Cl.CCc1cccc2ccn(CC3=NCCN3)c12 |t:11| Show InChI InChI=1S/C14H17N3.ClH/c1-2-11-4-3-5-12-6-9-17(14(11)12)10-13-15-7-8-16-13;/h3-6,9H,2,7-8,10H2,1H3,(H,15,16);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164832 (CHEMBL3797481) Show SMILES Cl.C(C1=NCCN1)n1ccc2ccccc12 |t:1| Show InChI InChI=1S/C12H13N3.ClH/c1-2-4-11-10(3-1)5-8-15(11)9-12-13-6-7-14-12;/h1-5,8H,6-7,9H2,(H,13,14);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50334207 (5-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...) Show SMILES Clc1ccc2n[nH]c(N=C3NCCN3)c2c1 |(28.5,-15.61,;29.85,-14.88,;29.89,-13.34,;31.24,-12.61,;32.55,-13.41,;34.03,-12.98,;34.9,-14.24,;33.97,-15.47,;34.78,-16.79,;36.31,-16.75,;37.19,-15.49,;38.66,-15.93,;38.69,-17.47,;37.24,-17.97,;32.52,-14.95,;31.16,-15.69,)| Show InChI InChI=1S/C10H10ClN5/c11-6-1-2-8-7(5-6)9(16-15-8)14-10-12-3-4-13-10/h1-2,5H,3-4H2,(H3,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting				Bioorg Med Chem 19: 321-9 (2011) Article DOI: 10.1016/j.bmc.2010.11.020 BindingDB Entry DOI: 10.7270/Q2FQ9WX5
					More data for this Ligand-Target Pair

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