Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human)) | BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Barrow Neurological Institute Curated by PDSP Ki Database | Mol Pharmacol 64: 1283-94 (2003) Article DOI: 10.1124/mol.64.6.1283 BindingDB Entry DOI: 10.7270/Q2GF0S2V | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122323 (US8729113, 35) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -53.1 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109401 (US8604061, 115) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50001885 ((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by PDSP Ki Database | Neuropsychopharmacology 28: 519-26 (2003) Article DOI: 10.1038/sj.npp.1300027 BindingDB Entry DOI: 10.7270/Q2833QKK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5 (Homo sapiens (Human)) | BDBM10484 (US11091471, Example RO-301 | US8846719, 301) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W66PWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250244 (US11697636, Example 154 | US9452980, 154) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.200 | -57.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122301 (US8729113, 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | -51.5 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109373 (US8604061, 48) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109462 (US8604061, 201) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250244 (US11697636, Example 154 | US9452980, 154) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human)) | BDBM86311 (CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Barrow Neurological Institute Curated by PDSP Ki Database | Mol Pharmacol 64: 1283-94 (2003) Article DOI: 10.1124/mol.64.6.1283 BindingDB Entry DOI: 10.7270/Q2GF0S2V | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50001888 ((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by PDSP Ki Database | Neuropsychopharmacology 28: 519-26 (2003) Article DOI: 10.1038/sj.npp.1300027 BindingDB Entry DOI: 10.7270/Q2833QKK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122333 (US8729113, 57) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -50.5 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250242 (US11697636, Example 152 | US9452980, 152) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -56.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250242 (US11697636, Example 152 | US9452980, 152) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50048803 (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by PDSP Ki Database | Neuropsychopharmacology 28: 519-26 (2003) Article DOI: 10.1038/sj.npp.1300027 BindingDB Entry DOI: 10.7270/Q2833QKK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109408 (US8604061, 127) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM109581 (US8604061, 316) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109564 (US8604061, 354) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122298 (US8729113, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -50.5 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122380 (US8729113, 136) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | -49.9 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250211 (US10501411, Example 121 | US11697636, Example 121 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250232 (US10501411, Example 142 | US11697636, Example 142 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr... | US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human)) | BDBM513240 (6-((5-methyl-3-(6-methylpyridazin-3-yl)isoxazol-4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W66PWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5 (Homo sapiens (Human)) | BDBM513334 (US11091471, Example RE-B) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s... | Citation and Details BindingDB Entry DOI: 10.7270/Q2W66PWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250211 (US10501411, Example 121 | US11697636, Example 121 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250232 (US10501411, Example 142 | US11697636, Example 142 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250240 (US11697636, Example 150 | US9452980, 150) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250240 (US11697636, Example 150 | US9452980, 150) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM250232 (US10501411, Example 142 | US11697636, Example 142 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109390 (US8604061, 103) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109446 (US8604061, 178) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109580 (US8604061, 296) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM109528 (US8604061, 298) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description Radioligand binding assay using TAAR1. | US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM122318 (US8729113, 30) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | -49.9 | n/a | n/a | n/a | n/a | n/a | n/a | 4 |
Hoffmann-La Roche Inc. US Patent | Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-... | US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW | |||||||||||
More data for this Ligand-Target Pair |
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