Compile Data Set for Download or QSAR

Found 986 hits with Last Name = 'ho' and Initial = 'kh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053067 ((2S,3S,4S)-3-Carboxymethyl-4-(1-phenyl-vinyl)-pyrr...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccccc1 Show InChI InChI=1S/C15H17NO4/c1-9(10-5-3-2-4-6-10)12-8-16-14(15(19)20)11(12)7-13(17)18/h2-6,11-12,14,16H,1,7-8H2,(H,17,18)(H,19,20)/t11-,12+,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053071 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-3-methyl...) Show SMILES Cc1cc(ccc1F)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H18FNO4/c1-8-5-10(3-4-13(8)17)9(2)12-7-18-15(16(21)22)11(12)6-14(19)20/h3-5,11-12,15,18H,2,6-7H2,1H3,(H,19,20)(H,21,22)/t11-,12+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053075 ((2S,3S,4S)-4-(1-Biphenyl-3-yl-vinyl)-3-carboxymeth...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C21H21NO4/c1-13(18-12-22-20(21(25)26)17(18)11-19(23)24)15-8-5-9-16(10-15)14-6-3-2-4-7-14/h2-10,17-18,20,22H,1,11-12H2,(H,23,24)(H,25,26)/t17-,18+,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053083 ((2S,3S,4S)-3-Carboxymethyl-4-(1-m-tolyl-vinyl)-pyr...) Show SMILES Cc1cccc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO4/c1-9-4-3-5-11(6-9)10(2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,2,7-8H2,1H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053080 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,4-dimethyl-phen...) Show SMILES Cc1ccc(cc1C)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C17H21NO4/c1-9-4-5-12(6-10(9)2)11(3)14-8-18-16(17(21)22)13(14)7-15(19)20/h4-6,13-14,16,18H,3,7-8H2,1-2H3,(H,19,20)(H,21,22)/t13-,14+,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053088 ((2S,3S,4S)-3-Carboxymethyl-4-(1-p-tolyl-vinyl)-pyr...) Show SMILES Cc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO4/c1-9-3-5-11(6-4-9)10(2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,2,7-8H2,1H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053087 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-phenyl)-...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(F)cc1 Show InChI InChI=1S/C15H16FNO4/c1-8(9-2-4-10(16)5-3-9)12-7-17-14(15(20)21)11(12)6-13(18)19/h2-5,11-12,14,17H,1,6-7H2,(H,18,19)(H,20,21)/t11-,12+,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053064 ((2S,3S,4S)-4-[1-(4-Butoxy-phenyl)-vinyl]-3-carboxy...) Show SMILES CCCCOc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C19H25NO5/c1-3-4-9-25-14-7-5-13(6-8-14)12(2)16-11-20-18(19(23)24)15(16)10-17(21)22/h5-8,15-16,18,20H,2-4,9-11H2,1H3,(H,21,22)(H,23,24)/t15-,16+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494356 (CHEMBL3088070) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053063 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methoxy-phenyl)...) Show SMILES COc1cccc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO5/c1-9(10-4-3-5-11(6-10)22-2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,1,7-8H2,2H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053059 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-propyl-phenyl)-...) Show SMILES CCCc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C18H23NO4/c1-3-4-12-5-7-13(8-6-12)11(2)15-10-19-17(18(22)23)14(15)9-16(20)21/h5-8,14-15,17,19H,2-4,9-10H2,1H3,(H,20,21)(H,22,23)/t14-,15+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053068 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-isopropenyl-phe...) Show SMILES CC(=C)c1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C18H21NO4/c1-10(2)12-4-6-13(7-5-12)11(3)15-9-19-17(18(22)23)14(15)8-16(20)21/h4-7,14-15,17,19H,1,3,8-9H2,2H3,(H,20,21)(H,22,23)/t14-,15+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053073 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-methoxy-phenyl)...) Show SMILES COc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO5/c1-9(10-3-5-11(22-2)6-4-10)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,1,7-8H2,2H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053061 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-chloro-phenyl)-...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H16ClNO4/c1-8(9-2-4-10(16)5-3-9)12-7-17-14(15(20)21)11(12)6-13(18)19/h2-5,11-12,14,17H,1,6-7H2,(H,18,19)(H,20,21)/t11-,12+,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053082 ((2S,3S,4S)-4-[1-(4-Butyl-phenyl)-vinyl]-3-carboxym...) Show SMILES CCCCc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C19H25NO4/c1-3-4-5-13-6-8-14(9-7-13)12(2)16-11-20-18(19(23)24)15(16)10-17(21)22/h6-9,15-16,18,20H,2-5,10-11H2,1H3,(H,21,22)(H,23,24)/t15-,16+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053065 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenethyloxy-ph...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(OCCc2ccccc2)cc1 Show InChI InChI=1S/C23H25NO5/c1-15(20-14-24-22(23(27)28)19(20)13-21(25)26)17-7-9-18(10-8-17)29-12-11-16-5-3-2-4-6-16/h2-10,19-20,22,24H,1,11-14H2,(H,25,26)(H,27,28)/t19-,20+,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053089 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-ethyl-phenyl)-v...) Show SMILES CCc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C17H21NO4/c1-3-11-4-6-12(7-5-11)10(2)14-9-18-16(17(21)22)13(14)8-15(19)20/h4-7,13-14,16,18H,2-3,8-9H2,1H3,(H,19,20)(H,21,22)/t13-,14+,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053070 ((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(1-methylene-pr...) Show SMILES CCC(=C)c1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C19H23NO4/c1-4-11(2)13-5-7-14(8-6-13)12(3)16-10-20-18(19(23)24)15(16)9-17(21)22/h5-8,15-16,18,20H,2-4,9-10H2,1H3,(H,21,22)(H,23,24)/t15-,16+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053076 ((2S,3S,4S)-4-(1-Biphenyl-4-yl-vinyl)-3-carboxymeth...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H21NO4/c1-13(18-12-22-20(21(25)26)17(18)11-19(23)24)14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,17-18,20,22H,1,11-12H2,(H,23,24)(H,25,26)/t17-,18+,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053062 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,5-dimethyl-phen...) Show SMILES Cc1cc(C)cc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C17H21NO4/c1-9-4-10(2)6-12(5-9)11(3)14-8-18-16(17(21)22)13(14)7-15(19)20/h4-6,13-14,16,18H,3,7-8H2,1-2H3,(H,19,20)(H,21,22)/t13-,14+,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053074 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenoxy-phenyl)...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C21H21NO5/c1-13(18-12-22-20(21(25)26)17(18)11-19(23)24)14-7-9-16(10-8-14)27-15-5-3-2-4-6-15/h2-10,17-18,20,22H,1,11-12H2,(H,23,24)(H,25,26)/t17-,18+,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053077 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-phenethyloxy-ph...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1cccc(OCCc2ccccc2)c1 Show InChI InChI=1S/C23H25NO5/c1-15(20-14-24-22(23(27)28)19(20)13-21(25)26)17-8-5-9-18(12-17)29-11-10-16-6-3-2-4-7-16/h2-9,12,19-20,22,24H,1,10-11,13-14H2,(H,25,26)(H,27,28)/t19-,20+,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053058 ((4E,6E)-(R)-7-[4,5-Bis-(1-hydroxy-vinyl)-pyrrolidi...) Show SMILES C[C@H](C=CC=C(C)C1CNC(C1C(C)=O)C(C)=O)C(C)=O |w:4.3| Show InChI InChI=1S/C17H25NO3/c1-10(12(3)19)7-6-8-11(2)15-9-18-17(14(5)21)16(15)13(4)20/h6-8,10,15-18H,9H2,1-5H3/t10-,15?,16?,17?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053060 ((2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-car...) Show SMILES CC(C)(C)c1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C19H25NO4/c1-11(12-5-7-13(8-6-12)19(2,3)4)15-10-20-17(18(23)24)14(15)9-16(21)22/h5-8,14-15,17,20H,1,9-10H2,2-4H3,(H,21,22)(H,23,24)/t14-,15+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494356 (CHEMBL3088070) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053079 ((2S,3S,4S)-4-[1-(3-Butoxy-phenyl)-vinyl]-3-carboxy...) Show SMILES CCCCOc1cccc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C19H25NO5/c1-3-4-8-25-14-7-5-6-13(9-14)12(2)16-11-20-18(19(23)24)15(16)10-17(21)22/h5-7,9,15-16,18,20H,2-4,8,10-11H2,1H3,(H,21,22)(H,23,24)/t15-,16+,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053067 ((2S,3S,4S)-3-Carboxymethyl-4-(1-phenyl-vinyl)-pyrr...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccccc1 Show InChI InChI=1S/C15H17NO4/c1-9(10-5-3-2-4-6-10)12-8-16-14(15(19)20)11(12)7-13(17)18/h2-6,11-12,14,16H,1,7-8H2,(H,17,18)(H,19,20)/t11-,12+,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053061 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-chloro-phenyl)-...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H16ClNO4/c1-8(9-2-4-10(16)5-3-9)12-7-17-14(15(20)21)11(12)6-13(18)19/h2-5,11-12,14,17H,1,6-7H2,(H,18,19)(H,20,21)/t11-,12+,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053087 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-phenyl)-...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(F)cc1 Show InChI InChI=1S/C15H16FNO4/c1-8(9-2-4-10(16)5-3-9)12-7-17-14(15(20)21)11(12)6-13(18)19/h2-5,11-12,14,17H,1,6-7H2,(H,18,19)(H,20,21)/t11-,12+,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053088 ((2S,3S,4S)-3-Carboxymethyl-4-(1-p-tolyl-vinyl)-pyr...) Show SMILES Cc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO4/c1-9-3-5-11(6-4-9)10(2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,2,7-8H2,1H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Homo sapiens (Human))	BDBM86754 (LY 466195 | LY-466195) Show SMILES OC(=O)C1CC(F)(F)CN1C[C@H]1CC[C@H]2CN[C@@H](C[C@H]2C1)C(O)=O |r| Show InChI InChI=1S/C16H24F2N2O4/c17-16(18)5-13(15(23)24)20(8-16)7-9-1-2-10-6-19-12(14(21)22)4-11(10)3-9/h9-13,19H,1-8H2,(H,21,22)(H,23,24)/t9-,10-,11+,12-,13?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP Ki Database									J Pharmacol Exp Ther 318: 772-81 (2006) Article DOI: 10.1124/jpet.106.101428 BindingDB Entry DOI: 10.7270/Q2NP230D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053071 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-fluoro-3-methyl...) Show SMILES Cc1cc(ccc1F)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H18FNO4/c1-8-5-10(3-4-13(8)17)9(2)12-7-18-15(16(21)22)11(12)6-14(19)20/h3-5,11-12,15,18H,2,6-7H2,1H3,(H,19,20)(H,21,22)/t11-,12+,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053073 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-methoxy-phenyl)...) Show SMILES COc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO5/c1-9(10-3-5-11(22-2)6-4-10)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,1,7-8H2,2H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM50257823 (CHEMBL4089551) Show SMILES Nc1nc(-c2ccc(cc2)S(N)(=O)=O)c2c(c[nH]c2n1)C#N Show InChI InChI=1S/C13H10N6O2S/c14-5-8-6-17-12-10(8)11(18-13(15)19-12)7-1-3-9(4-2-7)22(16,20)21/h1-4,6H,(H2,16,20,21)(H3,15,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde , 161 Cathedral Street, Glasgow G4 0NR, Scotland, United Kingdom. Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...				J Med Chem 60: 7043-7066 (2017) Article DOI: 10.1021/acs.jmedchem.7b00484 BindingDB Entry DOI: 10.7270/Q2M90C4N
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053089 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-ethyl-phenyl)-v...) Show SMILES CCc1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C17H21NO4/c1-3-11-4-6-12(7-5-11)10(2)14-9-18-16(17(21)22)13(14)8-15(19)20/h4-7,13-14,16,18H,2-3,8-9H2,1H3,(H,19,20)(H,21,22)/t13-,14+,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	82.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494342 (CHEMBL3088072) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1cccs1 |r| Show InChI InChI=1S/C21H23N5O3S.ClH/c27-21(28)17-9-14-8-15(5-3-13(14)11-22-17)29-18-10-12(19-2-1-7-30-19)4-6-16(18)20-23-25-26-24-20;/h1-2,4,6-7,10,13-15,17,22H,3,5,8-9,11H2,(H,27,28)(H,23,24,25,26);1H/t13-,14+,15-,17-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053075 ((2S,3S,4S)-4-(1-Biphenyl-3-yl-vinyl)-3-carboxymeth...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C21H21NO4/c1-13(18-12-22-20(21(25)26)17(18)11-19(23)24)15-8-5-9-16(10-15)14-6-3-2-4-7-14/h2-10,17-18,20,22H,1,11-12H2,(H,23,24)(H,25,26)/t17-,18+,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053063 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methoxy-phenyl)...) Show SMILES COc1cccc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO5/c1-9(10-4-3-5-11(6-10)22-2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,1,7-8H2,2H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50257884 (CHEMBL4065551) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1nc(N)nc2[nH]cc(C#N)c12 Show InChI InChI=1S/C14H12N6O2S/c1-23(21,22)20-10-4-2-8(3-5-10)12-11-9(6-15)7-17-13(11)19-14(16)18-12/h2-5,7,20H,1H3,(H3,16,17,18,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde , 161 Cathedral Street, Glasgow G4 0NR, Scotland, United Kingdom. Curated by ChEMBL					Assay Description Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...				J Med Chem 60: 7043-7066 (2017) Article DOI: 10.1021/acs.jmedchem.7b00484 BindingDB Entry DOI: 10.7270/Q2M90C4N
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50494350 (CHEMBL3088064) Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H25N5O3.ClH/c29-23(30)20-11-17-10-18(8-6-16(17)13-24-20)31-21-12-15(14-4-2-1-3-5-14)7-9-19(21)22-25-27-28-26-22;/h1-5,7,9,12,16-18,20,24H,6,8,10-11,13H2,(H,29,30)(H,25,26,27,28);1H/t16-,17+,18-,20-;/m0./s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]ATPA from human Gluk1 receptor				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053080 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3,4-dimethyl-phen...) Show SMILES Cc1ccc(cc1C)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C17H21NO4/c1-9-4-5-12(6-10(9)2)11(3)14-8-18-16(17(21)22)13(14)7-15(19)20/h4-6,13-14,16,18H,3,7-8H2,1-2H3,(H,19,20)(H,21,22)/t13-,14+,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50439332 (CHEMBL2419745) Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](NCC(O)=O)C(c2ccccc2)c2ccccc2)s1 |r| Show InChI InChI=1S/C28H31N5O4S/c29-26(30)22-14-13-20(38-22)16-32-27(36)21-12-7-15-33(21)28(37)25(31-17-23(34)35)24(18-8-3-1-4-9-18)19-10-5-2-6-11-19/h1-6,8-11,13-14,21,24-25,31H,7,12,15-17H2,(H3,29,30)(H,32,36)(H,34,35)/t21-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences Curated by ChEMBL					Assay Description Inhibition of human t-PA				Bioorg Med Chem Lett 23: 4779-84 (2013) Article DOI: 10.1016/j.bmcl.2013.07.008 BindingDB Entry DOI: 10.7270/Q2X92CR8
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053083 ((2S,3S,4S)-3-Carboxymethyl-4-(1-m-tolyl-vinyl)-pyr...) Show SMILES Cc1cccc(c1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C16H19NO4/c1-9-4-3-5-11(6-9)10(2)13-8-17-15(16(20)21)12(13)7-14(18)19/h3-6,12-13,15,17H,2,7-8H2,1H3,(H,18,19)(H,20,21)/t12-,13+,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50053066 ((2S,3S,4S)-3-Carboxymethyl-4-{1-[4-(5-phenyl-penty...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(OCCCCCc2ccccc2)cc1 Show InChI InChI=1S/C26H31NO5/c1-18(23-17-27-25(26(30)31)22(23)16-24(28)29)20-11-13-21(14-12-20)32-15-7-3-6-10-19-8-4-2-5-9-19/h2,4-5,8-9,11-14,22-23,25,27H,1,3,6-7,10,15-17H2,(H,28,29)(H,30,31)/t22-,23+,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053065 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-phenethyloxy-ph...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(OCCc2ccccc2)cc1 Show InChI InChI=1S/C23H25NO5/c1-15(20-14-24-22(23(27)28)19(20)13-21(25)26)17-7-9-18(10-8-17)29-12-11-16-5-3-2-4-6-16/h2-10,19-20,22,24H,1,11-14H2,(H,25,26)(H,27,28)/t19-,20+,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053084 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(3-methyl-4-phenet...) Show SMILES Cc1cc(ccc1OCCc1ccccc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-15-12-18(8-9-21(15)30-11-10-17-6-4-3-5-7-17)16(2)20-14-25-23(24(28)29)19(20)13-22(26)27/h3-9,12,19-20,23,25H,2,10-11,13-14H2,1H3,(H,26,27)(H,28,29)/t19-,20+,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053076 ((2S,3S,4S)-4-(1-Biphenyl-4-yl-vinyl)-3-carboxymeth...) Show SMILES OC(=O)C[C@H]1[C@H](CN[C@@H]1C(O)=O)C(=C)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H21NO4/c1-13(18-12-22-20(21(25)26)17(18)11-19(23)24)14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,17-18,20,22H,1,11-12H2,(H,23,24)(H,25,26)/t17-,18+,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50053068 ((2S,3S,4S)-3-Carboxymethyl-4-[1-(4-isopropenyl-phe...) Show SMILES CC(=C)c1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O Show InChI InChI=1S/C18H21NO4/c1-10(2)12-4-6-13(7-5-12)11(3)15-9-19-17(18(22)23)14(15)8-16(20)21/h4-7,14-15,17,19H,1,3,8-9H2,2H3,(H,20,21)(H,22,23)/t14-,15+,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2				J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ
					More data for this Ligand-Target Pair

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