Compile Data Set for Download or QSAR

Found 85 hits with Last Name = 'thrasher' and Initial = 'kj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243396 (CHEMBL1231520) Show SMILES Nc1nc2ccc(NS(=O)(=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1 |r| Show InChI InChI=1S/C20H19N5O8S/c21-20-23-14-6-3-11(9-13(14)18(29)24-20)25-34(32,33)12-4-1-10(2-5-12)17(28)22-15(19(30)31)7-8-16(26)27/h1-6,9,15,25H,7-8H2,(H,22,28)(H,26,27)(H,30,31)(H3,21,23,24,29)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human AICARFT				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50006878 ((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled gastrin binding to gastrin receptor in guinea pig brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243461 (CHEMBL4075503) Show SMILES Fc1cc2cc[nH]c(=O)c2cc1NS(=O)(=O)c1ccc(s1)-c1ccc(=O)[nH]c1 Show InChI InChI=1S/C18H12FN3O4S2/c19-13-7-10-5-6-20-18(24)12(10)8-14(13)22-28(25,26)17-4-2-15(27-17)11-1-3-16(23)21-9-11/h1-9,22H,(H,20,24)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243462 (CHEMBL4083899) Show SMILES CC1(C)CC(=CNC1=O)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |c:4| Show InChI InChI=1S/C20H18FN3O4S2/c1-20(2)9-12(10-23-19(20)26)16-3-4-17(29-16)30(27,28)24-15-8-13-11(7-14(15)21)5-6-22-18(13)25/h3-8,10,24H,9H2,1-2H3,(H,22,25)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243463 (CHEMBL4100363) Show SMILES CCC1(C)CC(=CNC1=O)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |c:5| Show InChI InChI=1S/C21H20FN3O4S2/c1-3-21(2)10-13(11-24-20(21)27)17-4-5-18(30-17)31(28,29)25-16-9-14-12(8-15(16)22)6-7-23-19(14)26/h4-9,11,25H,3,10H2,1-2H3,(H,23,26)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50006878 ((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50006878 ((R)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benz...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(C)cc2)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C24H22N4O2/c1-16-12-14-18(15-13-16)25-24(30)27-22-23(29)28(2)20-11-7-6-10-19(20)21(26-22)17-8-4-3-5-9-17/h3-15,22H,1-2H3,(H2,25,27,30)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled CCK-8 sulfate binding to CCK-B receptor in mouse brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243486 (CHEMBL4081385) Show SMILES O[C@@H]1CN(C[C@@H]1F)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H15F2N3O4S2/c18-11-5-9-3-4-20-17(24)10(9)6-13(11)21-28(25,26)16-2-1-15(27-16)22-7-12(19)14(23)8-22/h1-6,12,14,21,23H,7-8H2,(H,20,24)/t12-,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50006842 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropox...) Show SMILES CC(C)Oc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O2/c1-17(2)33-21-7-5-6-20(15-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-16-29-24-12-11-19(28)14-23(18)24/h3-9,11-12,14-17,29H,10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243487 (CHEMBL4091668) Show SMILES O[C@@H]1CN(CC1(F)F)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H14F3N3O4S2/c18-11-5-9-3-4-21-16(25)10(9)6-12(11)22-29(26,27)15-2-1-14(28-15)23-7-13(24)17(19,20)8-23/h1-6,13,22,24H,7-8H2,(H,21,25)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243441 (CHEMBL4076500) Show SMILES OC1CCN(CC1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F Show InChI InChI=1S/C18H18FN3O4S2/c19-14-9-11-3-6-20-18(24)13(11)10-15(14)21-28(25,26)17-2-1-16(27-17)22-7-4-12(23)5-8-22/h1-3,6,9-10,12,21,23H,4-5,7-8H2,(H,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243443 (CHEMBL4070790) Show SMILES O[C@H]1CN(CC1(F)F)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H14F3N3O4S2/c18-11-5-9-3-4-21-16(25)10(9)6-12(11)22-29(26,27)15-2-1-14(28-15)23-7-13(24)17(19,20)8-23/h1-6,13,22,24H,7-8H2,(H,21,25)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243485 (CHEMBL4074469) Show SMILES O[C@H]1CCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H16FN3O4S2/c18-13-7-10-3-5-19-17(23)12(10)8-14(13)20-27(24,25)16-2-1-15(26-16)21-6-4-11(22)9-21/h1-3,5,7-8,11,20,22H,4,6,9H2,(H,19,23)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011943 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-dimethyla...) Show SMILES CN(C)c1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H23BrN4O/c1-30(2)19-6-5-7-20(15-19)31-25(29-24-9-4-3-8-21(24)26(31)32)13-10-17-16-28-23-12-11-18(27)14-22(17)23/h3-9,11-12,14-16,28H,10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243415 (CHEMBL4063104) Show SMILES O[C@@H]1CCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H16FN3O4S2/c18-13-7-10-3-5-19-17(23)12(10)8-14(13)20-27(24,25)16-2-1-15(26-16)21-6-4-11(22)9-21/h1-3,5,7-8,11,20,22H,4,6,9H2,(H,19,23)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243434 (CHEMBL4079085) Show SMILES O[C@H]1CCCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C18H18FN3O4S2/c19-14-8-11-5-6-20-18(24)13(11)9-15(14)21-28(25,26)17-4-3-16(27-17)22-7-1-2-12(23)10-22/h3-6,8-9,12,21,23H,1-2,7,10H2,(H,20,24)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243442 (CHEMBL4099409) Show SMILES O[C@H]1CN(C[C@H]1F)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C17H15F2N3O4S2/c18-11-5-9-3-4-20-17(24)10(9)6-13(11)21-28(25,26)16-2-1-15(27-16)22-7-12(19)14(23)8-22/h1-6,12,14,21,23H,7-8H2,(H,20,24)/t12-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50006838 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl...) Show SMILES CC(C)Oc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H25N3O2/c1-18(2)32-21-9-7-8-20(16-21)30-26(29-25-13-6-4-11-23(25)27(30)31)15-14-19-17-28-24-12-5-3-10-22(19)24/h3-13,16-18,28H,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243433 (CHEMBL4101204) Show SMILES O[C@@H]1CCCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F |r| Show InChI InChI=1S/C18H18FN3O4S2/c19-14-8-11-5-6-20-18(24)13(11)9-15(14)21-28(25,26)17-4-3-16(27-17)22-7-1-2-12(23)10-22/h3-6,8-9,12,21,23H,1-2,7,10H2,(H,20,24)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011957 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-ethyl-phe...) Show SMILES CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H22BrN3O/c1-2-17-7-11-20(12-8-17)30-25(29-24-6-4-3-5-21(24)26(30)31)14-9-18-16-28-23-13-10-19(27)15-22(18)23/h3-8,10-13,15-16,28H,2,9,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011939 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-methoxy-p...) Show SMILES COc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3O2/c1-31-19-10-8-18(9-11-19)29-24(28-23-5-3-2-4-20(23)25(29)30)13-6-16-15-27-22-12-7-17(26)14-21(16)22/h2-5,7-12,14-15,27H,6,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011953 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-dimethyla...) Show SMILES CN(C)c1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H23BrN4O/c1-30(2)19-9-11-20(12-10-19)31-25(29-24-6-4-3-5-21(24)26(31)32)14-7-17-16-28-23-13-8-18(27)15-22(17)23/h3-6,8-13,15-16,28H,7,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011954 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-methylsul...) Show SMILES CSc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3OS/c1-31-19-10-8-18(9-11-19)29-24(28-23-5-3-2-4-20(23)25(29)30)13-6-16-15-27-22-12-7-17(26)14-21(16)22/h2-5,7-12,14-15,27H,6,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011965 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-isopropyl...) Show SMILES CC(C)c1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O/c1-17(2)18-7-11-21(12-8-18)31-26(30-25-6-4-3-5-22(25)27(31)32)14-9-19-16-29-24-13-10-20(28)15-23(19)24/h3-8,10-13,15-17,29H,9,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011942 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-methoxy-p...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011942 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-methoxy-p...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011948 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-methylsul...) Show SMILES CSc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3OS/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011940 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-ethyl-phe...) Show SMILES CCc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H22BrN3O/c1-2-17-6-5-7-20(14-17)30-25(29-24-9-4-3-8-21(24)26(30)31)13-10-18-16-28-23-12-11-19(27)15-22(18)23/h3-9,11-12,14-16,28H,2,10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011945 (2-[2-(5-Chloro-1H-indol-3-yl)-ethyl]-3-(3-methoxy-...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Cl)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20ClN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011946 (3-(3-Methoxy-phenyl)-2-[2-(5-methyl-1H-indol-3-yl)...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(C)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H23N3O2/c1-17-10-12-23-22(14-17)18(16-27-23)11-13-25-28-24-9-4-3-8-21(24)26(30)29(25)19-6-5-7-20(15-19)31-2/h3-10,12,14-16,27H,11,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011950 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-propoxy-p...) Show SMILES CCCOc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O2/c1-2-14-33-21-7-5-6-20(16-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-17-29-24-12-11-19(28)15-23(18)24/h3-9,11-12,15-17,29H,2,10,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011966 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-cyclopent...) Show SMILES Brc1ccc2[nH]cc(CCc3nc4ccccc4c(=O)n3-c3cccc(OC4CCCC4)c3)c2c1 Show InChI InChI=1S/C29H26BrN3O2/c30-20-13-14-26-25(16-20)19(18-31-26)12-15-28-32-27-11-4-3-10-24(27)29(34)33(28)21-6-5-9-23(17-21)35-22-7-1-2-8-22/h3-6,9-11,13-14,16-18,22,31H,1-2,7-8,12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011958 (2-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-3-(3-methoxy...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(OC)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H23N3O3/c1-31-19-7-5-6-18(14-19)29-25(28-24-9-4-3-8-21(24)26(29)30)13-10-17-16-27-23-12-11-20(32-2)15-22(17)23/h3-9,11-12,14-16,27H,10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011962 (3-(3-Ethyl-phenyl)-2-[2-(1H-indol-3-yl)-ethyl]-3H-...) Show SMILES CCc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H23N3O/c1-2-18-8-7-9-20(16-18)29-25(28-24-13-6-4-11-22(24)26(29)30)15-14-19-17-27-23-12-5-3-10-21(19)23/h3-13,16-17,27H,2,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50006842 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropox...) Show SMILES CC(C)Oc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O2/c1-17(2)33-21-7-5-6-20(15-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-16-29-24-12-11-19(28)14-23(18)24/h3-9,11-12,14-17,29H,10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011961 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-ethoxy-ph...) Show SMILES CCOc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H22BrN3O2/c1-2-32-20-11-9-19(10-12-20)30-25(29-24-6-4-3-5-21(24)26(30)31)14-7-17-16-28-23-13-8-18(27)15-22(17)23/h3-6,8-13,15-16,28H,2,7,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011952 (2-[2-(5-Bromo-1H-indol-3-yl)-propyl]-3-(3-ethyl-ph...) Show SMILES CCc1cccc(c1)-n1c(CC(C)c2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O/c1-3-18-7-6-8-20(14-18)31-26(30-25-10-5-4-9-21(25)27(31)32)13-17(2)23-16-29-24-12-11-19(28)15-22(23)24/h4-12,14-17,29H,3,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011947 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-isopropox...) Show SMILES CC(C)Oc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O2/c1-17(2)33-21-11-9-20(10-12-21)31-26(30-25-6-4-3-5-22(25)27(31)32)14-7-18-16-29-24-13-8-19(28)15-23(18)24/h3-6,8-13,15-17,29H,7,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011941 (2-[2-(5-Fluoro-1H-indol-3-yl)-ethyl]-3-(3-methoxy-...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(F)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20FN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011964 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3,4-dimetho...) Show SMILES COc1ccc(cc1OC)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H22BrN3O3/c1-32-23-11-9-18(14-24(23)33-2)30-25(29-22-6-4-3-5-19(22)26(30)31)12-7-16-15-28-21-10-8-17(27)13-20(16)21/h3-6,8-11,13-15,28H,7,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011949 (2-[2-(1H-Indol-3-yl)-ethyl]-3-m-tolyl-3H-quinazoli...) Show SMILES Cc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H21N3O/c1-17-7-6-8-19(15-17)28-24(27-23-12-5-3-10-21(23)25(28)29)14-13-18-16-26-22-11-4-2-9-20(18)22/h2-12,15-16,26H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50006842 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropox...) Show SMILES CC(C)Oc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H24BrN3O2/c1-17(2)33-21-7-5-6-20(15-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-16-29-24-12-11-19(28)14-23(18)24/h3-9,11-12,14-17,29H,10,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled gastrin binding to gastrin/cholecystokinin type B receptor				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011956 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-methoxy-phenyl)-3...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H21N3O2/c1-30-19-8-6-7-18(15-19)28-24(27-23-12-5-3-10-21(23)25(28)29)14-13-17-16-26-22-11-4-2-9-20(17)22/h2-12,15-16,26H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011963 (3-Benzo[1,3]dioxol-5-yl-2-[2-(1H-indol-3-yl)-ethyl...) Show SMILES O=c1n(c(CCc2c[nH]c3ccccc23)nc2ccccc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C25H19N3O3/c29-25-19-6-2-4-8-21(19)27-24(12-9-16-14-26-20-7-3-1-5-18(16)20)28(25)17-10-11-22-23(13-17)31-15-30-22/h1-8,10-11,13-14,26H,9,12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011960 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-trifluoro...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H17BrF3N3O/c26-17-9-10-21-20(13-17)15(14-30-21)8-11-23-31-22-7-2-1-6-19(22)24(33)32(23)18-5-3-4-16(12-18)25(27,28)29/h1-7,9-10,12-14,30H,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50011940 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-ethyl-phe...) Show SMILES CCc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C26H22BrN3O/c1-2-17-6-5-7-20(14-17)30-25(29-24-9-4-3-8-21(24)26(30)31)13-10-18-16-28-23-12-11-19(27)15-22(18)23/h3-9,11-12,14-16,28H,2,10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled CCK-8 sulfate binding to CCK-B receptor in guinea pig brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50011942 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-methoxy-p...) Show SMILES COc1cccc(c1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3O2/c1-31-19-6-4-5-18(14-19)29-24(28-23-8-3-2-7-20(23)25(29)30)12-9-16-15-27-22-11-10-17(26)13-21(16)22/h2-8,10-11,13-15,27H,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled CCK-8 sulfate binding to Cholecystokinin type B receptor in guinea pig brain membranes				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011959 (3-(3-Bromo-phenyl)-2-[2-(1H-indol-3-yl)-ethyl]-3H-...) Show SMILES Brc1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C24H18BrN3O/c25-17-6-5-7-18(14-17)28-23(27-22-11-4-2-9-20(22)24(28)29)13-12-16-15-26-21-10-3-1-8-19(16)21/h1-11,14-15,26H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011955 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-trifluoromethyl-p...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H18F3N3O/c26-25(27,28)17-6-5-7-18(14-17)31-23(30-22-11-4-2-9-20(22)24(31)32)13-12-16-15-29-21-10-3-1-8-19(16)21/h1-11,14-15,29H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human))	BDBM50243477 (CHEMBL4092503) Show SMILES O=c1[nH]ccc2ccc(NS(=O)(=O)c3ccc(cc3)C#N)cc12 Show InChI InChI=1S/C16H11N3O3S/c17-10-11-1-5-14(6-2-11)23(21,22)19-13-4-3-12-7-8-18-16(20)15(12)9-13/h1-9,19H,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	608	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...				J Med Chem 60: 9599-9616 (2017) Article DOI: 10.1021/acs.jmedchem.7b01046 BindingDB Entry DOI: 10.7270/Q2222X6J
					More data for this Ligand-Target Pair

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