Compile Data Set for Download or QSAR

Found 90 hits with Last Name = 'takayama' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242558 (US9422240, 1-353) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)nc2)C1=O |c:7| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Rattus norvegicus (Rat))	BDBM242558 (US9422240, 1-353) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)nc2)C1=O |c:7| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of rat PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242528 (US9422240, 1-70) Show SMILES Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:15| Show InChI InChI=1S/C21H21N3O6/c1-13-2-5-15(6-3-13)30-17-7-4-14(10-22-17)12-24-9-8-16(25)19(21(24)29)20(28)23-11-18(26)27/h2-7,10,25H,8-9,11-12H2,1H3,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242531 (US9422240, 1-209) Show SMILES Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cc2)cc1 |t:15| Show InChI InChI=1S/C22H22N2O6/c1-14-2-6-16(7-3-14)30-17-8-4-15(5-9-17)13-24-11-10-18(25)20(22(24)29)21(28)23-12-19(26)27/h2-9,25H,10-13H2,1H3,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50272039 (CHEMBL4129773) Show SMILES [Na;v0+].[#6]-c1ccc(-[#8]-c2ccc(-[#6]-[#7]-3-[#6]-[#6]-[#6](-[#8])=[#6](-[#6](=O)-[#7]-[#6]-[#6](-[#8-])=O)-[#6]-3=O)nc2)cc1 |t:15| Show InChI InChI=1S/C21H21N3O6/c1-13-2-5-15(6-3-13)30-16-7-4-14(22-10-16)12-24-9-8-17(25)19(21(24)29)20(28)23-11-18(26)27/h2-7,10,25H,8-9,11-12H2,1H3,(H,23,28)(H,26,27)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50460324 (CHEMBL4226885) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCC4)c(F)c3)C2)CC1 Show InChI InChI=1S/C25H35FN2O4/c1-18(2)32-24(30)28-12-8-25(9-13-28)16-19(17-25)5-3-14-31-20-6-7-21(22(26)15-20)23(29)27-10-4-11-27/h6-7,15,18-19H,3-5,8-14,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50460305 (CHEMBL4227731) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCCC4)c(F)c3)C2)CC1 Show InChI InChI=1S/C26H37FN2O4/c1-19(2)33-25(31)29-13-9-26(10-14-29)17-20(18-26)6-5-15-32-21-7-8-22(23(27)16-21)24(30)28-11-3-4-12-28/h7-8,16,19-20H,3-6,9-15,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50460324 (CHEMBL4226885) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCC4)c(F)c3)C2)CC1 Show InChI InChI=1S/C25H35FN2O4/c1-18(2)32-24(30)28-12-8-25(9-13-28)16-19(17-25)5-3-14-31-20-6-7-21(22(26)15-20)23(29)27-10-4-11-27/h6-7,15,18-19H,3-5,8-14,16-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50460305 (CHEMBL4227731) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCCC4)c(F)c3)C2)CC1 Show InChI InChI=1S/C26H37FN2O4/c1-19(2)33-25(31)29-13-9-26(10-14-29)17-20(18-26)6-5-15-32-21-7-8-22(23(27)16-21)24(30)28-11-3-4-12-28/h7-8,16,19-20H,3-6,9-15,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP1A2 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50460309 (CHEMBL4226586) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CC(O)C4)c(F)c3)C2)CC1 Show InChI InChI=1S/C25H35FN2O5/c1-17(2)33-24(31)27-9-7-25(8-10-27)13-18(14-25)4-3-11-32-20-5-6-21(22(26)12-20)23(30)28-15-19(29)16-28/h5-6,12,17-19,29H,3-4,7-11,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50460309 (CHEMBL4226586) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CC(O)C4)c(F)c3)C2)CC1 Show InChI InChI=1S/C25H35FN2O5/c1-17(2)33-24(31)27-9-7-25(8-10-27)13-18(14-25)4-3-11-32-20-5-6-21(22(26)12-20)23(30)28-15-19(29)16-28/h5-6,12,17-19,29H,3-4,7-11,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50460305 (CHEMBL4227731) Show SMILES CC(C)OC(=O)N1CCC2(CC(CCCOc3ccc(C(=O)N4CCCC4)c(F)c3)C2)CC1 Show InChI InChI=1S/C26H37FN2O4/c1-19(2)33-25(31)29-13-9-26(10-14-29)17-20(18-26)6-5-15-32-21-7-8-22(23(27)16-21)24(30)28-11-3-4-12-28/h7-8,16,19-20H,3-6,9-15,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes				Bioorg Med Chem 26: 1832-1847 (2018) Article DOI: 10.1016/j.bmc.2018.02.032 BindingDB Entry DOI: 10.7270/Q2K64MQB
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186221 (CHEMBL3822759) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-23(2,3)31-22(28)26-11-9-18(10-12-26)27-21-15-24-20(13-17(21)14-25-27)16-5-7-19(8-6-16)32(4,29)30/h5-8,13-15,18H,9-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186222 (CHEMBL3822500) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C22H26N4O4S/c1-15(2)30-22(27)25-10-8-18(9-11-25)26-21-14-23-20(12-17(21)13-24-26)16-4-6-19(7-5-16)31(3,28)29/h4-7,12-15,18H,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186338 (CHEMBL3823329) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(=O)NCCO Show InChI InChI=1S/C26H27F2N7O2/c1-2-16-12-31-26(32-13-16)34-6-3-18(4-7-34)35-24-15-30-23(9-17(24)14-33-35)19-10-22(28)20(11-21(19)27)25(37)29-5-8-36/h9-15,18,36H,2-8H2,1H3,(H,29,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186339 (CHEMBL3823780) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)S(C)(=O)=O Show InChI InChI=1S/C24H25FN6O2S/c1-3-16-12-27-24(28-13-16)30-8-6-18(7-9-30)31-23-15-26-22(10-17(23)14-29-31)20-5-4-19(11-21(20)25)34(2,32)33/h4-5,10-15,18H,3,6-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186340 (CHEMBL3823396) Show SMILES CC(C)(OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C23H25F3N4O4S/c1-23(2,21(25)26)34-22(31)29-8-6-15(7-9-29)30-20-13-27-19(10-14(20)12-28-30)17-5-4-16(11-18(17)24)35(3,32)33/h4-5,10-13,15,21H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186341 (CHEMBL3823489) Show SMILES CC(C)CCN1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H30N4O2S/c1-17(2)8-11-26-12-9-20(10-13-26)27-23-16-24-22(14-19(23)15-25-27)18-4-6-21(7-5-18)30(3,28)29/h4-7,14-17,20H,8-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186342 (CHEMBL3822863) Show SMILES Cc1ccc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H25N5O2S/c1-17-3-8-24(26-14-17)28-11-9-20(10-12-28)29-23-16-25-22(13-19(23)15-27-29)18-4-6-21(7-5-18)32(2,30)31/h3-8,13-16,20H,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186343 (CHEMBL3824187) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H26N6O2S/c1-3-17-13-26-24(27-14-17)29-10-8-20(9-11-29)30-23-16-25-22(12-19(23)15-28-30)18-4-6-21(7-5-18)33(2,31)32/h4-7,12-16,20H,3,8-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186344 (CHEMBL3822488) Show SMILES CC(C)(OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C23H26F2N4O4S/c1-23(2,21(24)25)33-22(30)28-10-8-17(9-11-28)29-20-14-26-19(12-16(20)13-27-29)15-4-6-18(7-5-15)34(3,31)32/h4-7,12-14,17,21H,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186345 (CHEMBL3822762) Show SMILES CC(C)COC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-16(2)15-31-23(28)26-10-8-19(9-11-26)27-22-14-24-21(12-18(22)13-25-27)17-4-6-20(7-5-17)32(3,29)30/h4-7,12-14,16,19H,8-11,15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186346 (CHEMBL3823972) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(=O)NCCO Show InChI InChI=1S/C24H27F2N5O4/c1-14(2)35-24(34)30-6-3-16(4-7-30)31-22-13-28-21(9-15(22)12-29-31)17-10-20(26)18(11-19(17)25)23(33)27-5-8-32/h9-14,16,32H,3-8H2,1-2H3,(H,27,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186347 (CHEMBL3824111) Show SMILES CCCNC(=O)c1cc(F)c(cc1F)-c1cc2cnn(C3CCN(CC3)C(=O)OC(C)C)c2cn1 Show InChI InChI=1S/C25H29F2N5O3/c1-4-7-28-24(33)19-12-20(26)18(11-21(19)27)22-10-16-13-30-32(23(16)14-29-22)17-5-8-31(9-6-17)25(34)35-15(2)3/h10-15,17H,4-9H2,1-3H3,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186348 (CHEMBL3824019) Show SMILES CCNC(=O)c1cc(F)c(cc1F)-c1cc2cnn(C3CCN(CC3)C(=O)OC(C)C)c2cn1 Show InChI InChI=1S/C24H27F2N5O3/c1-4-27-23(32)18-11-19(25)17(10-20(18)26)21-9-15-12-29-31(22(15)13-28-21)16-5-7-30(8-6-16)24(33)34-14(2)3/h9-14,16H,4-8H2,1-3H3,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186349 (CHEMBL3823379) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(=O)N(C)C Show InChI InChI=1S/C24H27F2N5O3/c1-14(2)34-24(33)30-7-5-16(6-8-30)31-22-13-27-21(9-15(22)12-28-31)17-10-20(26)18(11-19(17)25)23(32)29(3)4/h9-14,16H,5-8H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186350 (CHEMBL3823398) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(N)=O Show InChI InChI=1S/C22H23F2N5O3/c1-12(2)32-22(31)28-5-3-14(4-6-28)29-20-11-26-19(7-13(20)10-27-29)15-8-18(24)16(21(25)30)9-17(15)23/h7-12,14H,3-6H2,1-2H3,(H2,25,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186351 (CHEMBL3822567) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)C(N)=O Show InChI InChI=1S/C22H24FN5O3/c1-13(2)31-22(30)27-7-5-16(6-8-27)28-20-12-25-19(10-15(20)11-26-28)17-4-3-14(21(24)29)9-18(17)23/h3-4,9-13,16H,5-8H2,1-2H3,(H2,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186352 (CHEMBL3823669) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)S(C)(=O)=O Show InChI InChI=1S/C22H25FN4O4S/c1-14(2)31-22(28)26-8-6-16(7-9-26)27-21-13-24-20(10-15(21)12-25-27)18-5-4-17(11-19(18)23)32(3,29)30/h4-5,10-14,16H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186353 (CHEMBL3824150) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(nc1)S(C)(=O)=O Show InChI InChI=1S/C21H25N5O4S/c1-14(2)30-21(27)25-8-6-17(7-9-25)26-19-13-22-18(10-16(19)12-24-26)15-4-5-20(23-11-15)31(3,28)29/h4-5,10-14,17H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	197	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186609 (CHEMBL3823744) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(Oc3cccc(c3)S(C)(=O)=O)ncc12 Show InChI InChI=1S/C22H26N4O5S/c1-15(2)30-22(27)25-9-7-17(8-10-25)26-20-14-23-21(11-16(20)13-24-26)31-18-5-4-6-19(12-18)32(3,28)29/h4-6,11-15,17H,7-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	266	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186719 (CHEMBL3822545) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(Oc3ccc(cc3)S(C)(=O)=O)ncc12 Show InChI InChI=1S/C22H26N4O5S/c1-15(2)30-22(27)25-10-8-17(9-11-25)26-20-14-23-21(12-16(20)13-24-26)31-18-4-6-19(7-5-18)32(3,28)29/h4-7,12-15,17H,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	177	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186722 (CHEMBL3823123) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-23(2,3)31-22(28)26-13-11-18(12-14-26)27-21-10-7-17(15-20(21)24-25-27)16-5-8-19(9-6-16)32(4,29)30/h5-10,15,18H,11-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186725 (CHEMBL3823843) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H29N3O4S/c1-24(2,3)31-23(28)26-13-11-20(12-14-26)27-22-10-7-18(15-19(22)16-25-27)17-5-8-21(9-6-17)32(4,29)30/h5-10,15-16,20H,11-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.050 BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268843 (CHEMBL4086175) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C25H27N5O2S/c1-3-18-15-26-25(27-16-18)29-12-10-22(11-13-29)30-24-9-6-20(14-21(24)17-28-30)19-4-7-23(8-5-19)33(2,31)32/h4-9,14-17,22H,3,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268844 (CHEMBL4059986) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1nnc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H25N7O2S/c1-3-16-13-25-23(26-14-16)29-10-8-18(9-11-29)30-22-15-24-20(12-21(22)27-28-30)17-4-6-19(7-5-17)33(2,31)32/h4-7,12-15,18H,3,8-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268845 (CHEMBL4088233) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1nnc2cc(ccc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H26N6O2S/c1-3-17-15-25-24(26-16-17)29-12-10-20(11-13-29)30-23-9-6-19(14-22(23)27-28-30)18-4-7-21(8-5-18)33(2,31)32/h4-9,14-16,20H,3,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268846 (CHEMBL4104975) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2c(C)c(ccc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C26H29N5O2S/c1-4-19-15-27-26(28-16-19)30-13-11-21(12-14-30)31-25-10-9-23(18(2)24(25)17-29-31)20-5-7-22(8-6-20)34(3,32)33/h5-10,15-17,21H,4,11-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268847 (CHEMBL4080747) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(c(C)cc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C26H29N5O2S/c1-4-19-15-27-26(28-16-19)30-11-9-22(10-12-30)31-25-13-18(2)24(14-21(25)17-29-31)20-5-7-23(8-6-20)34(3,32)33/h5-8,13-17,22H,4,9-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268848 (CHEMBL4087339) Show SMILES CCNC(=O)c1ccc(c(C)c1)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C26H30N8O/c1-4-18-14-29-26(30-15-18)33-10-8-20(9-11-33)34-24-16-28-22(13-23(24)31-32-34)21-7-6-19(12-17(21)3)25(35)27-5-2/h6-7,12-16,20H,4-5,8-11H2,1-3H3,(H,27,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268849 (CHEMBL4099323) Show SMILES CCNC(=O)c1ccc(c(Cl)c1)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C25H27ClN8O/c1-3-16-13-29-25(30-14-16)33-9-7-18(8-10-33)34-23-15-28-21(12-22(23)31-32-34)19-6-5-17(11-20(19)26)24(35)27-4-2/h5-6,11-15,18H,3-4,7-10H2,1-2H3,(H,27,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268850 (CHEMBL4072376) Show SMILES CCNC(=O)c1ccc(-c2cc3nnn(C4CCN(CC4)c4ncc(CC)cn4)c3cn2)c(c1)C(F)(F)F Show InChI InChI=1S/C26H27F3N8O/c1-3-16-13-32-25(33-14-16)36-9-7-18(8-10-36)37-23-15-31-21(12-22(23)34-35-37)19-6-5-17(24(38)30-4-2)11-20(19)26(27,28)29/h5-6,11-15,18H,3-4,7-10H2,1-2H3,(H,30,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268851 (CHEMBL4065009) Show SMILES CCNC(=O)c1ccc(cc1Cl)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C25H27ClN8O/c1-3-16-13-29-25(30-14-16)33-9-7-18(8-10-33)34-23-15-28-21(12-22(23)31-32-34)17-5-6-19(20(26)11-17)24(35)27-4-2/h5-6,11-15,18H,3-4,7-10H2,1-2H3,(H,27,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268852 (CHEMBL4073169) Show SMILES CCNC(=O)c1ccc(cc1C(F)(F)F)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C26H27F3N8O/c1-3-16-13-32-25(33-14-16)36-9-7-18(8-10-36)37-23-15-31-21(12-22(23)34-35-37)17-5-6-19(24(38)30-4-2)20(11-17)26(27,28)29/h5-6,11-15,18H,3-4,7-10H2,1-2H3,(H,30,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268853 (CHEMBL4064583) Show SMILES CCNC(=O)c1c(C)cc(cc1C)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C27H32N8O/c1-5-19-14-30-27(31-15-19)34-9-7-21(8-10-34)35-24-16-29-22(13-23(24)32-33-35)20-11-17(3)25(18(4)12-20)26(36)28-6-2/h11-16,21H,5-10H2,1-4H3,(H,28,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186222 (CHEMBL3822500) Show SMILES CC(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C22H26N4O4S/c1-15(2)30-22(27)25-10-8-18(9-11-25)26-21-14-23-20(12-17(21)13-24-26)16-4-6-19(7-5-16)31(3,28)29/h4-7,12-15,18H,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268854 (CHEMBL4068645) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1nnc2cc(ncc12)-c1ccc(c(F)c1)S(C)(=O)=O Show InChI InChI=1S/C23H24FN7O2S/c1-3-15-12-26-23(27-13-15)30-8-6-17(7-9-30)31-21-14-25-19(11-20(21)28-29-31)16-4-5-22(18(24)10-16)34(2,32)33/h4-5,10-14,17H,3,6-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186221 (CHEMBL3822759) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C23H28N4O4S/c1-23(2,3)31-22(28)26-11-9-18(10-12-26)27-21-15-24-20(13-17(21)14-25-27)16-5-7-19(8-6-16)32(4,29)30/h5-8,13-15,18H,9-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268855 (CHEMBL4103709) Show SMILES CCNC(=O)c1ccc(c(F)c1)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C25H27FN8O/c1-3-16-13-29-25(30-14-16)33-9-7-18(8-10-33)34-23-15-28-21(12-22(23)31-32-34)19-6-5-17(11-20(19)26)24(35)27-4-2/h5-6,11-15,18H,3-4,7-10H2,1-2H3,(H,27,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268856 (CHEMBL4079458) Show SMILES CCNC(=O)c1cc(F)c(cc1F)-c1cc2nnn(C3CCN(CC3)c3ncc(CC)cn3)c2cn1 Show InChI InChI=1S/C25H26F2N8O/c1-3-15-12-30-25(31-13-15)34-7-5-16(6-8-34)35-23-14-29-21(11-22(23)32-33-35)17-9-20(27)18(10-19(17)26)24(36)28-4-2/h9-14,16H,3-8H2,1-2H3,(H,28,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells assessed as stimulation of cAMP level measured after 30 mins by HTRF assay				Bioorg Med Chem 25: 4339-4354 (2017) Article DOI: 10.1016/j.bmc.2017.06.014 BindingDB Entry DOI: 10.7270/Q21V5HFG
					More data for this Ligand-Target Pair

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