Compile Data Set for Download or QSAR

Found 53 hits with Last Name = 'slayden' and Initial = 'od'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50375821 (TANAPROGET) Show SMILES Cn1c(ccc1-c1ccc2NC(=S)OC(C)(C)c2c1)C#N Show InChI InChI=1S/C16H15N3OS/c1-16(2)12-8-10(4-6-13(12)18-15(21)20-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human GR ligand binding domain expressed in african green monkey COS7 cells in presence of Dexamethasone by Gal4 hybrid assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50375823 (CHEMBL407847) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C22CCCC2)c(F)c1)C#N Show InChI InChI=1S/C18H16FN3O/c1-22-12(10-20)4-5-15(22)11-8-13-16(14(19)9-11)21-17(23)18(13)6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375817 (CHEMBL272663) Show SMILES CCC1(CC)C(=O)Nc2ccc(cc12)-c1ccc(C#N)n1C Show InChI InChI=1S/C18H19N3O/c1-4-18(5-2)14-10-12(6-8-15(14)20-17(18)22)16-9-7-13(11-19)21(16)3/h6-10H,4-5H2,1-3H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50144435 (1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCCC3)c2c1)C#N Show InChI InChI=1S/C19H19N3O/c1-22-14(12-20)6-8-17(22)13-5-7-16-15(11-13)19(18(23)21-16)9-3-2-4-10-19/h5-8,11H,2-4,9-10H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375822 (CHEMBL408648) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C22CCCCC2)c(F)c1)C#N Show InChI InChI=1S/C19H18FN3O/c1-23-13(11-21)5-6-16(23)12-9-14-17(15(20)10-12)22-18(24)19(14)7-3-2-4-8-19/h5-6,9-10H,2-4,7-8H2,1H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375827 (CHEMBL407848 | WAY-255348) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-9(7-12(17)14(11)19-15(16)21)13-5-4-10(8-18)20(13)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375831 (CHEMBL429572) Show SMILES Cn1c(ccc1-c1cc2c(N(CC=C)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C19H18FN3O/c1-5-8-23-17-14(19(2,3)18(23)24)9-12(10-15(17)20)16-7-6-13(11-21)22(16)4/h5-7,9-10H,1,8H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375824 (CHEMBL429928) Show SMILES CCC1(CC)C(=O)Nc2c1cc(cc2F)-c1ccc(C#N)n1C Show InChI InChI=1S/C18H18FN3O/c1-4-18(5-2)13-8-11(9-14(19)16(13)21-17(18)23)15-7-6-12(10-20)22(15)3/h6-9H,4-5H2,1-3H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50144438 (5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)OC(C)(C)c2c1)C#N Show InChI InChI=1S/C16H15N3O2/c1-16(2)12-8-10(4-6-13(12)18-15(20)21-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375827 (CHEMBL407848 | WAY-255348) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-9(7-12(17)14(11)19-15(16)21)13-5-4-10(8-18)20(13)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375826 (CHEMBL270714) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C(C)(C)c2c1F)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)13-11(19-15(16)21)6-5-10(14(13)17)12-7-4-9(8-18)20(12)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375826 (CHEMBL270714) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C(C)(C)c2c1F)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)13-11(19-15(16)21)6-5-10(14(13)17)12-7-4-9(8-18)20(12)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human AR ligand binding domain expressed in african green monkey COS7 cells in presence of 5-alpha-dihydrotestosterone by Gal4...				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human AR ligand binding domain expressed in african green monkey COS7 cells in presence of 5-alpha-dihydrotestosterone by Gal4...				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375818 (CHEMBL270908) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C(C)(C)c2c1)C#N Show InChI InChI=1S/C16H15N3O/c1-16(2)12-8-10(4-6-13(12)18-15(16)20)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375834 (CHEMBL271804) Show SMILES CC(C)N1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C19H20FN3O/c1-11(2)23-17-14(19(3,4)18(23)24)8-12(9-15(17)20)16-7-6-13(10-21)22(16)5/h6-9,11H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375823 (CHEMBL407847) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C22CCCC2)c(F)c1)C#N Show InChI InChI=1S/C18H16FN3O/c1-22-12(10-20)4-5-15(22)11-8-13-16(14(19)9-11)21-17(23)18(13)6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50121163 (3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...) Show SMILES O=C1Nc2ccc(cc2C11CCCCC1)-c1cccc(c1)C#N Show InChI InChI=1S/C20H18N2O/c21-13-14-5-4-6-15(11-14)16-7-8-18-17(12-16)20(19(23)22-18)9-2-1-3-10-20/h4-8,11-12H,1-3,9-10H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375836 (CHEMBL271552) Show SMILES CN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C17H16FN3O/c1-17(2)12-7-10(14-6-5-11(9-19)20(14)3)8-13(18)15(12)21(4)16(17)22/h5-8H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375819 (CHEMBL270052) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)Cc2c1)C#N Show InChI InChI=1S/C14H11N3O/c1-17-11(8-15)3-5-13(17)9-2-4-12-10(6-9)7-14(18)16-12/h2-6H,7H2,1H3,(H,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375825 (CHEMBL406235) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)cc1F)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-10(12(17)7-13(11)19-15(16)21)14-5-4-9(8-18)20(14)3/h4-7H,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375818 (CHEMBL270908) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C(C)(C)c2c1)C#N Show InChI InChI=1S/C16H15N3O/c1-16(2)12-8-10(4-6-13(12)18-15(16)20)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375839 (CHEMBL271149) Show SMILES Cn1c(ccc1-c1cc2c(N(C3CCCC3)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C21H22FN3O/c1-21(2)16-10-13(18-9-8-15(12-23)24(18)3)11-17(22)19(16)25(20(21)26)14-6-4-5-7-14/h8-11,14H,4-7H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50121163 (3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indo...) Show SMILES O=C1Nc2ccc(cc2C11CCCCC1)-c1cccc(c1)C#N Show InChI InChI=1S/C20H18N2O/c21-13-14-5-4-6-15(11-14)16-7-8-18-17(12-16)20(19(23)22-18)9-2-1-3-10-20/h4-8,11-12H,1-3,9-10H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50121164 (3-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-b...) Show SMILES CC1(C)C(=O)Nc2ccc(cc12)-c1cccc(c1)C#N Show InChI InChI=1S/C17H14N2O/c1-17(2)14-9-13(6-7-15(14)19-16(17)20)12-5-3-4-11(8-12)10-18/h3-9H,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375835 (CHEMBL437801) Show SMILES CCCN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C19H20FN3O/c1-5-8-23-17-14(19(2,3)18(23)24)9-12(10-15(17)20)16-7-6-13(11-21)22(16)4/h6-7,9-10H,5,8H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375840 (CHEMBL405428) Show SMILES CCN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C18H18FN3O/c1-5-22-16-13(18(2,3)17(22)23)8-11(9-14(16)19)15-7-6-12(10-20)21(15)4/h6-9H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375833 (CHEMBL437622) Show SMILES CC(C)CN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C20H22FN3O/c1-12(2)11-24-18-15(20(3,4)19(24)25)8-13(9-16(18)21)17-7-6-14(10-22)23(17)5/h6-9,12H,11H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375830 (CHEMBL271175) Show SMILES Cn1c(ccc1-c1cc2c(N(CC#C)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C19H16FN3O/c1-5-8-23-17-14(19(2,3)18(23)24)9-12(10-15(17)20)16-7-6-13(11-21)22(16)4/h1,6-7,9-10H,8H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375817 (CHEMBL272663) Show SMILES CCC1(CC)C(=O)Nc2ccc(cc12)-c1ccc(C#N)n1C Show InChI InChI=1S/C18H19N3O/c1-4-18(5-2)14-10-12(6-8-15(14)20-17(18)22)16-9-7-13(11-19)21(16)3/h6-10H,4-5H2,1-3H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375828 (CHEMBL271336) Show SMILES CC(=O)OCN1C(=O)C(C)(C)c2cc(cc(F)c12)-c1ccc(C#N)n1C Show InChI InChI=1S/C19H18FN3O3/c1-11(24)26-10-23-17-14(19(2,3)18(23)25)7-12(8-15(17)20)16-6-5-13(9-21)22(16)4/h5-8H,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375819 (CHEMBL270052) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)Cc2c1)C#N Show InChI InChI=1S/C14H11N3O/c1-17-11(8-15)3-5-13(17)9-2-4-12-10(6-9)7-14(18)16-12/h2-6H,7H2,1H3,(H,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human GR ligand binding domain expressed in african green monkey COS7 cells in presence of Dexamethasone by Gal4 hybrid assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375838 (CHEMBL271835) Show SMILES Cn1c(ccc1-c1cc2c(N(Cc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C23H20FN3O/c1-23(2)18-11-16(20-10-9-17(13-25)26(20)3)12-19(24)21(18)27(22(23)28)14-15-7-5-4-6-8-15/h4-12H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375832 (CHEMBL408696) Show SMILES Cn1c(ccc1-c1cc2c(N(C3CCCCC3)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C22H24FN3O/c1-22(2)17-11-14(19-10-9-16(13-24)25(19)3)12-18(23)20(17)26(21(22)27)15-7-5-4-6-8-15/h9-12,15H,4-8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50375827 (CHEMBL407848 | WAY-255348) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-9(7-12(17)14(11)19-15(16)21)13-5-4-10(8-18)20(13)3/h4-7H,1-3H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human AR ligand binding domain expressed in african green monkey COS7 cells in presence of 5-alpha-dihydrotestosterone by Gal4...				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375820 (CHEMBL270909) Show SMILES O=C1Cc2cc(ccc2N1)-c1ccc([nH]1)C#N Show InChI InChI=1S/C13H9N3O/c14-7-10-2-4-11(15-10)8-1-3-12-9(5-8)6-13(17)16-12/h1-5,15H,6H2,(H,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375829 (CHEMBL409147) Show SMILES Cn1c(ccc1-c1cc2c(N(CCc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C24H22FN3O/c1-24(2)19-13-17(21-10-9-18(15-26)27(21)3)14-20(25)22(19)28(23(24)29)12-11-16-7-5-4-6-8-16/h4-10,13-14H,11-12H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human MR ligand binding domain expressed in african green monkey COS7 cells in presence of aldosterone by Gal4 hybrid assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50375423 (ASOPRISNIL) Show SMILES COC[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(CN=O)cc1)OC |r,c:17,t:10| Show InChI InChI=1S/C28H35NO4/c1-27-15-24(19-6-4-18(5-7-19)16-29-31)26-22-11-9-21(30)14-20(22)8-10-23(26)25(27)12-13-28(27,33-3)17-32-2/h4-7,14,23-25H,8-13,15-17H2,1-3H3/t23-,24+,25-,27-,28+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human ER ligand binding domain expressed in african green monkey COS7 cells in presence of 17-beta-estradiol by Gal4 hybrid as...				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50375827 (CHEMBL407848 | WAY-255348) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C16H14FN3O/c1-16(2)11-6-9(7-12(17)14(11)19-15(16)21)13-5-4-10(8-18)20(13)3/h4-7H,1-3H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human MR ligand binding domain expressed in african green monkey COS7 cells in presence of aldosterone by Gal4 hybrid assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375823 (CHEMBL407847) Show SMILES Cn1c(ccc1-c1cc2c(NC(=O)C22CCCC2)c(F)c1)C#N Show InChI InChI=1S/C18H16FN3O/c1-22-12(10-20)4-5-15(22)11-8-13-16(14(19)9-11)21-17(23)18(13)6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375821 (TANAPROGET) Show SMILES Cn1c(ccc1-c1ccc2NC(=S)OC(C)(C)c2c1)C#N Show InChI InChI=1S/C16H15N3OS/c1-16(2)12-8-10(4-6-13(12)18-15(21)20-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50144435 (1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCCC3)c2c1)C#N Show InChI InChI=1S/C19H19N3O/c1-22-14(12-20)6-8-17(22)13-5-7-16-15(11-13)19(18(23)21-16)9-3-2-4-10-19/h5-8,11H,2-4,9-10H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair

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