Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442711 (CHEMBL2442509) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442711 (CHEMBL2442509) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442710 (CHEMBL1303766) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442718 (CHEMBL2442512) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442710 (CHEMBL1303766) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442717 (CHEMBL2442515) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442716 (CHEMBL2442510) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442715 (CHEMBL2442513) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442714 (CHEMBL1830821) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442713 (CHEMBL2442514) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442712 (CHEMBL2442508) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442701 (CHEMBL2074836) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442702 (CHEMBL2442511 | US9296728, 26) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442703 (CHEMBL2442507) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442706 (CHEMBL2442504) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442705 (CHEMBL2442505) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442704 (CHEMBL2442506) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442709 (CHEMBL2442516) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442708 (CHEMBL2442517) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442707 (CHEMBL2442503) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM50442701 (CHEMBL2074836) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Exp£rimentale et Clinique (IREC) Curated by ChEMBL | Assay Description Inhibition of MCT4-mediated [14C]-lactate uptake in human SiHa cells in lactate-containing medium assessed as remaining lactate concentration in cult... | Bioorg Med Chem 21: 7107-17 (2013) Article DOI: 10.1016/j.bmc.2013.09.010 BindingDB Entry DOI: 10.7270/Q2H133G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527817 (CHEMBL4466441) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.11E+9 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disruption by n... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.33E+8 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H I8A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50527803 (CHEMBL4557180) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.17E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Competitive binding affinity to human N-terminal His6-tagged LDH-5 expressed in Escherichia coli Rosetta (DE3) assessed as protein-compound interacti... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527818 (CHEMBL4575384) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.05E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527816 (CHEMBL4452577) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527815 (CHEMBL4468125) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.42E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527814 (CHEMBL4471310) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527813 (CHEMBL4456560) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9.78E+8 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H T2A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527812 (CHEMBL4475220) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.49E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527805 (CHEMBL4440124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.02E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) in sodium phosphate buffer at pH 7.6 b... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527803 (CHEMBL4557180) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant full length human His-tagged LDH-1 (1 to 322 residues) expressed in Escherichia coli assessed as protein-... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527811 (CHEMBL4450669) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 4.65E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527810 (CHEMBL4532326) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.13E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527809 (CHEMBL4456178) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527808 (CHEMBL4582140) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.98E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527807 (CHEMBL4525659) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.87E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527806 (CHEMBL4437918) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527805 (CHEMBL4440124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.05E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9.54E+8 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H K6A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.01E+9 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H E5A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527804 (CHEMBL4453053) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.78E+6 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) measured after 5 mins by Red-NHS fluor... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9.91E+8 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H K4A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50527803 (CHEMBL4557180) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) after 5 mins by Red-NHS fluorescence dye... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50420178 (GUANIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.24E+8 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity full length human N-terminal His6-tagged LDH-H L3A mutant expressed in Escherichia coli Rosetta (DE3) assessed as tetrameric disrupt... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50527803 (CHEMBL4557180) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.72E+5 | n/a | n/a | n/a | n/a |
Universit£ Catholique de Louvain (UCLouvain) Curated by ChEMBL | Assay Description Binding affinity to human N-terminal His6-tagged human LDH-5 expressed in Escherichia coli Rosetta (DE3) assessed as induction of protein disruption ... | J Med Chem 63: 4628-4643 (2020) Article DOI: 10.1021/acs.jmedchem.9b01955 BindingDB Entry DOI: 10.7270/Q2TB1BCZ | |||||||||||
More data for this Ligand-Target Pair |