Compile Data Set for Download or QSAR

Found 877 hits with Last Name = 'rault' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399621 (CHEMBL2181166) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399622 (CHEMBL2181168) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399623 (CHEMBL2181169) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50293279 (1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...) Show SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 Show InChI InChI=1S/C19H25N3OS/c1-3-8-21-10-6-15(7-11-21)12-23-18-16-5-4-9-22(16)17-14(2)13-24-19(17)20-18/h4-5,9,13,15H,3,6-8,10-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399621 (CHEMBL2181166) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50108392 ((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...) Show SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12 |r,THB:9:7:4.3:1| Show InChI InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity at 5HT3 receptor				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399619 (CHEMBL2181189) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
Protein O-GlcNAcase (Homo sapiens (Human))	BDBM50456904 (CHEMBL4218693) Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](NC(=O)\C=C\C=C)c2nc(CCc3ccccc3)cn12 |r| Show InChI InChI=1S/C21H25N3O4/c1-2-3-9-17(26)23-18-20(28)19(27)16(13-25)24-12-15(22-21(18)24)11-10-14-7-5-4-6-8-14/h2-9,12,16,18-20,25,27-28H,1,10-11,13H2,(H,23,26)/b9-3+/t16-,18-,19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Caen Normandie Curated by ChEMBL					Assay Description Competitive inhibition of human O-GlcNAcase by Lineweaver-Burk analysis				Eur J Med Chem 139: 153-167 (2017) Article DOI: 10.1016/j.ejmech.2017.07.070 BindingDB Entry DOI: 10.7270/Q2ZP48QF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399622 (CHEMBL2181168) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399616 (CHEMBL2181188) Show SMILES CCCN1CCC(COc2nc3c(Cl)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413548 (CHEMBL512679) Show SMILES CCCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 Show InChI InChI=1S/C20H27N3OS/c1-3-4-9-22-11-7-16(8-12-22)13-24-19-17-6-5-10-23(17)18-15(2)14-25-20(18)21-19/h5-6,10,14,16H,3-4,7-9,11-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210122 (CHEMBL234881 | [2-(2',6'-dimethyl-biphenyl-3-yl)-e...) Show SMILES CN(C)CCc1cccc(c1)-c1c(C)cccc1C Show InChI InChI=1S/C18H23N/c1-14-7-5-8-15(2)18(14)17-10-6-9-16(13-17)11-12-19(3)4/h5-10,13H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413547 (CHEMBL448702) Show SMILES CC(C)N1CCC(COc2nc3scc(C)c3n3cccc23)CC1 Show InChI InChI=1S/C19H25N3OS/c1-13(2)21-9-6-15(7-10-21)11-23-18-16-5-4-8-22(16)17-14(3)12-24-19(17)20-18/h4-5,8,12-13,15H,6-7,9-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399615 (CHEMBL2181171) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210124 (2-(2'-methyl-biphenyl-3-yl)-ethylamine | CHEMBL234...) Show SMILES Cc1ccccc1-c1cccc(CCN)c1 Show InChI InChI=1S/C15H17N/c1-12-5-2-3-8-15(12)14-7-4-6-13(11-14)9-10-16/h2-8,11H,9-10,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210123 (CHEMBL395870 | N,N-dimethyl-2-(2'-methylbiphenyl-3...) Show SMILES CN(C)CCc1cccc(c1)-c1ccccc1C Show InChI InChI=1S/C17H21N/c1-14-7-4-5-10-17(14)16-9-6-8-15(13-16)11-12-18(2)3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210126 (CHEMBL232792 | [2-(2'-methoxy-biphenyl-3-yl)-ethyl...) Show SMILES COc1ccccc1-c1cccc(CCN(C)C)c1 Show InChI InChI=1S/C17H21NO/c1-18(2)12-11-14-7-6-8-15(13-14)16-9-4-5-10-17(16)19-3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413546 (CHEMBL513254) Show SMILES Cc1csc2nc(OCC3CCN(CC=C)CC3)c3cccn3c12 Show InChI InChI=1S/C19H23N3OS/c1-3-8-21-10-6-15(7-11-21)12-23-18-16-5-4-9-22(16)17-14(2)13-24-19(17)20-18/h3-5,9,13,15H,1,6-8,10-12H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210125 (CHEMBL232791 | [2-(2',6'-dimethoxy-biphenyl-3-yl)-...) Show SMILES COc1cccc(OC)c1-c1cccc(CCN(C)C)c1 Show InChI InChI=1S/C18H23NO2/c1-19(2)12-11-14-7-5-8-15(13-14)18-16(20-3)9-6-10-17(18)21-4/h5-10,13H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413545 (CHEMBL469575) Show SMILES C=CCN1CCC(COc2nc3ccsc3n3cccc23)CC1 Show InChI InChI=1S/C18H21N3OS/c1-2-8-20-10-5-14(6-11-20)13-22-17-16-4-3-9-21(16)18-15(19-17)7-12-23-18/h2-4,7,9,12,14H,1,5-6,8,10-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413544 (CHEMBL511794) Show SMILES CCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 Show InChI InChI=1S/C18H23N3OS/c1-3-20-9-6-14(7-10-20)11-22-17-15-5-4-8-21(15)16-13(2)12-23-18(16)19-17/h4-5,8,12,14H,3,6-7,9-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity to rat 5HT1A				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122722 (9-Butyl-5-(piperidin-4-ylmethoxy)-1,2,3,4-tetrahyd...) Show SMILES CCCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C22H31N3O/c1-2-3-13-25-14-10-17(11-15-25)16-26-22-19-8-6-12-23-21(19)18-7-4-5-9-20(18)24-22/h4-5,7,9,17,23H,2-3,6,8,10-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122721 (6-(1-Ethyl-piperidin-4-ylmethoxy)-8,9,10,11-tetrah...) Show SMILES CCN1CCC(COc2nc3ccccc3c3NCCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-24-13-10-16(11-14-24)15-25-21-18-8-5-6-12-22-20(18)17-7-3-4-9-19(17)23-21/h3-4,7,9,16,22H,2,5-6,8,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413543 (CHEMBL472481) Show SMILES Cc1csc2nc(OCC3CCN(CCC=C)CC3)c3cccn3c12 Show InChI InChI=1S/C20H25N3OS/c1-3-4-9-22-11-7-16(8-12-22)13-24-19-17-6-5-10-23(17)18-15(2)14-25-20(18)21-19/h3,5-6,10,14,16H,1,4,7-9,11-13H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413542 (CHEMBL469582) Show SMILES CCCN1CCC(COc2nc3sccc3n3cccc23)CC1 Show InChI InChI=1S/C18H23N3OS/c1-2-8-20-10-5-14(6-11-20)13-22-17-15-4-3-9-21(15)16-7-12-23-18(16)19-17/h3-4,7,9,12,14H,2,5-6,8,10-11,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413541 (CHEMBL469593) Show SMILES Cc1csc2nc(OCCCN3CCCCC3)c3cccn3c12 Show InChI InChI=1S/C18H23N3OS/c1-14-13-23-18-16(14)21-11-5-7-15(21)17(19-18)22-12-6-10-20-8-3-2-4-9-20/h5,7,11,13H,2-4,6,8-10,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122718 (6-(1-Propyl-piperidin-4-ylmethoxy)-8,9,10,11-tetra...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCCc23)CC1 Show InChI InChI=1S/C22H31N3O/c1-2-13-25-14-10-17(11-15-25)16-26-22-19-8-5-6-12-23-21(19)18-7-3-4-9-20(18)24-22/h3-4,7,9,17,23H,2,5-6,8,10-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122719 (9-Pentyl-5-(piperidin-4-ylmethoxy)-1,2,3,4-tetrahy...) Show SMILES CCCCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C23H33N3O/c1-2-3-6-14-26-15-11-18(12-16-26)17-27-23-20-9-7-13-24-22(20)19-8-4-5-10-21(19)25-23/h4-5,8,10,18,24H,2-3,6-7,9,11-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122723 (9-Ethyl-5-(piperidin-4-ylmethoxy)-1,2,3,4-tetrahyd...) Show SMILES CCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C20H27N3O/c1-2-23-12-9-15(10-13-23)14-24-20-17-7-5-11-21-19(17)16-6-3-4-8-18(16)22-20/h3-4,6,8,15,21H,2,5,7,9-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399615 (CHEMBL2181171) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399623 (CHEMBL2181169) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50122720 (6-(1-Butyl-piperidin-4-ylmethoxy)-8,9,10,11-tetrah...) Show SMILES CCCCN1CCC(COc2nc3ccccc3c3NCCCCc23)CC1 Show InChI InChI=1S/C23H33N3O/c1-2-3-14-26-15-11-18(12-16-26)17-27-23-20-9-6-7-13-24-22(20)19-8-4-5-10-21(19)25-23/h4-5,8,10,18,24H,2-3,6-7,9,11-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413539 (CHEMBL450595) Show SMILES CCN(CC)CCCCOc1nc2ccsc2n2cccc12 Show InChI InChI=1S/C17H23N3OS/c1-3-19(4-2)10-5-6-12-21-16-15-8-7-11-20(15)17-14(18-16)9-13-22-17/h7-9,11,13H,3-6,10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413540 (CHEMBL471662) Show SMILES CCCN1CCC(COc2nc3ccsc3n3cccc23)CC1 Show InChI InChI=1S/C18H23N3OS/c1-2-8-20-10-5-14(6-11-20)13-22-17-16-4-3-9-21(16)18-15(19-17)7-12-23-18/h3-4,7,9,12,14H,2,5-6,8,10-11,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399620 (CHEMBL2181187) Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50413538 (CHEMBL516340) Show SMILES CC(C)N1CCC(COc2nc3ccsc3n3cccc23)CC1 Show InChI InChI=1S/C18H23N3OS/c1-13(2)20-9-5-14(6-10-20)12-22-17-16-4-3-8-21(16)18-15(19-17)7-11-23-18/h3-4,7-8,11,13-14H,5-6,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane				Bioorg Med Chem 17: 2607-22 (2009) Article DOI: 10.1016/j.bmc.2008.11.045 BindingDB Entry DOI: 10.7270/Q2CJ8DCG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity to rat 5HT1A				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair

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