Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50282059 (CHEMBL433452 | quinuclidine derivative) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement. | Bioorg Med Chem Lett 3: 1555-1558 (1993) Article DOI: 10.1016/S0960-894X(00)80017-7 BindingDB Entry DOI: 10.7270/Q2J38SHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50230657 (CHEMBL290493) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0295 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM29611 (2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0324 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50133069 (3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470184 (CHEMBL304203) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50035202 (CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0724 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470187 (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470007 (CHEMBL322269) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470000 (CHEMBL111599) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.141 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50280507 (6-Amino-2-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI) | Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50282053 (4-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement. | Bioorg Med Chem Lett 3: 1555-1558 (1993) Article DOI: 10.1016/S0960-894X(00)80017-7 BindingDB Entry DOI: 10.7270/Q2J38SHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50280507 (6-Amino-2-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-benzo[d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligand | Bioorg Med Chem Lett 4: 945-948 (1994) Article DOI: 10.1016/S0960-894X(01)80269-9 BindingDB Entry DOI: 10.7270/Q20V8D8T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50133070 (CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM9019 (CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Effect of compound on Melatonin receptor in chicken brain in the presence of MnCl2 | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470172 (CHEMBL294517) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Effect of compound on Melatonin receptor in chicken brain in the presence of MnCl2 | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50408556 (CHEMBL37771) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056419 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortex | Bioorg Med Chem Lett 5: 795-798 (1995) Article DOI: 10.1016/0960-894X(95)00115-A BindingDB Entry DOI: 10.7270/Q2R78FP7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056419 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement. | Bioorg Med Chem Lett 3: 1555-1558 (1993) Article DOI: 10.1016/S0960-894X(00)80017-7 BindingDB Entry DOI: 10.7270/Q2J38SHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056419 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligand | Bioorg Med Chem Lett 4: 945-948 (1994) Article DOI: 10.1016/S0960-894X(01)80269-9 BindingDB Entry DOI: 10.7270/Q20V8D8T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056419 (4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN) | Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470187 (CHEMBL428882) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50133070 (CHEMBL335465 | [1,1';2',1'']Terphenyl-4'-carbaldeh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 3: 2035-2038 (1993) Article DOI: 10.1016/S0960-894X(01)81009-X BindingDB Entry DOI: 10.7270/Q2XW4JQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50123807 (4-Amino-N-(8-benzoyl-8-aza-bicyclo[3.2.1]oct-3-yl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatum | Bioorg Med Chem Lett 5: 795-798 (1995) Article DOI: 10.1016/0960-894X(95)00115-A BindingDB Entry DOI: 10.7270/Q2R78FP7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50366367 (CHEMBL1788272) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligand | Bioorg Med Chem Lett 4: 945-948 (1994) Article DOI: 10.1016/S0960-894X(01)80269-9 BindingDB Entry DOI: 10.7270/Q20V8D8T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470180 (CHEMBL61626) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.389 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470180 (CHEMBL61626) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50084878 (Butyl-[8-(2,4-dichloro-phenyl)-2,7-dimethyl-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1 | J Med Chem 43: 449-56 (2000) BindingDB Entry DOI: 10.7270/Q2542P9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM9019 (CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description In vitro binding affinity against melatonin receptor using 2-[125I]iodomelatonin (0.05 nM) and chicken brain membranes | J Med Chem 39: 3089-95 (1996) Article DOI: 10.1021/jm960219h BindingDB Entry DOI: 10.7270/Q2736TNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50133069 (3'-Ethylamino-[1,1';2',1'']terphenyl-4'-carbaldehy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50280498 (6-Amino-2-(1-aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI) | Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50035179 (Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.537 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470174 (CHEMBL62992) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50035179 (Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470174 (CHEMBL62992) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50084876 (CHEMBL344223 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1 | J Med Chem 43: 449-56 (2000) BindingDB Entry DOI: 10.7270/Q2542P9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM9019 (CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM9019 (CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470172 (CHEMBL294517) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Paris-Sud Curated by ChEMBL | Assay Description Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligand | J Med Chem 40: 739-48 (1997) Article DOI: 10.1021/jm960680+ BindingDB Entry DOI: 10.7270/Q2WQ06H4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470172 (CHEMBL294517) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranes | J Med Chem 38: 2050-60 (1995) Article DOI: 10.1021/jm00012a004 BindingDB Entry DOI: 10.7270/Q2ZS307H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056396 (4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortex | Bioorg Med Chem Lett 4: 1433-1436 (1994) Article DOI: 10.1016/S0960-894X(01)80508-4 BindingDB Entry DOI: 10.7270/Q2G160RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50084880 (CHEMBL140894 | Cyclopropylmethyl-[8-(2,4-dichloro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1 | J Med Chem 43: 449-56 (2000) BindingDB Entry DOI: 10.7270/Q2542P9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50056396 (4-Amino-5-chloro-2-methoxy-benzoic acid (S)-(1-aza...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement. | Bioorg Med Chem Lett 3: 1555-1558 (1993) Article DOI: 10.1016/S0960-894X(00)80017-7 BindingDB Entry DOI: 10.7270/Q2J38SHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50000492 ((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortex | Bioorg Med Chem Lett 4: 1433-1436 (1994) Article DOI: 10.1016/S0960-894X(01)80508-4 BindingDB Entry DOI: 10.7270/Q2G160RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melatonin receptor type 1C (Gallus gallus) | BDBM50470867 (CHEMBL318179) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS-BIOCIS Curated by ChEMBL | Assay Description In vitro binding affinity against melatonin receptor using 2-[125I]iodomelatonin (0.05 nM) and chicken brain membranes | J Med Chem 39: 3089-95 (1996) Article DOI: 10.1021/jm960219h BindingDB Entry DOI: 10.7270/Q2736TNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT) | BDBM50280497 ((R)-2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-benzo[de]isoq...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH) | Bioorg Med Chem Lett 2: 691-694 (1992) Article DOI: 10.1016/S0960-894X(00)80392-3 BindingDB Entry DOI: 10.7270/Q2B85814 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 4 (RAT) | BDBM29526 (2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatum | Bioorg Med Chem Lett 4: 1433-1436 (1994) Article DOI: 10.1016/S0960-894X(01)80508-4 BindingDB Entry DOI: 10.7270/Q2G160RF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | 1.09 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description The compound was evaluated for binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal membranes using [3H]-8-OH-DPAT as radiolig... | Bioorg Med Chem Lett 3: 2035-2038 (1993) Article DOI: 10.1016/S0960-894X(01)81009-X BindingDB Entry DOI: 10.7270/Q2XW4JQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50133071 (3'-Hydroxy-[1,1';2',1'']terphenyl-4'-carbaldehyde ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Pisa Curated by ChEMBL | Assay Description Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiol | J Med Chem 46: 4032-42 (2003) Article DOI: 10.1021/jm0308390 BindingDB Entry DOI: 10.7270/Q27W6BKS | |||||||||||
More data for this Ligand-Target Pair |
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