Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human H3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50383118 (CHEMBL2031738) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to rat H3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human H3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor A (RAT) | BDBM50161275 (CHEMBL3787059) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Donghua University Curated by ChEMBL | Assay Description Displacement of [125I]-Ang II from Angiotensin 2 type-1A receptor in rat vascular smooth muscle cells after 150 mins by gamma counting method | Bioorg Med Chem 24: 2023-31 (2016) Article DOI: 10.1016/j.bmc.2016.03.028 BindingDB Entry DOI: 10.7270/Q2XW4MQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor A (RAT) | BDBM50161276 (CHEMBL3786570) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Donghua University Curated by ChEMBL | Assay Description Displacement of [125I]-Ang II from Angiotensin 2 type-1A receptor in rat vascular smooth muscle cells after 150 mins by gamma counting method | Bioorg Med Chem 24: 2023-31 (2016) Article DOI: 10.1016/j.bmc.2016.03.028 BindingDB Entry DOI: 10.7270/Q2XW4MQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor A (RAT) | BDBM50161277 (CHEMBL3787050) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Donghua University Curated by ChEMBL | Assay Description Displacement of [125I]-Ang II from Angiotensin 2 type-1A receptor in rat vascular smooth muscle cells after 150 mins by gamma counting method | Bioorg Med Chem 24: 2023-31 (2016) Article DOI: 10.1016/j.bmc.2016.03.028 BindingDB Entry DOI: 10.7270/Q2XW4MQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor A (RAT) | BDBM82258 (CAS_114798-26-4 | Losartan | NSC_3961) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Donghua University Curated by ChEMBL | Assay Description Displacement of [125I]-Ang II from Angiotensin 2 type-1A receptor in rat vascular smooth muscle cells after 150 mins by gamma counting method | Bioorg Med Chem 24: 2023-31 (2016) Article DOI: 10.1016/j.bmc.2016.03.028 BindingDB Entry DOI: 10.7270/Q2XW4MQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM27213 (4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human H3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cocaine esterase (Homo sapiens (Human)) | BDBM50571105 (CHEMBL4851375) | NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Non-competitive inhibition of CES2 in human liver microsomes using fluorescein diacetate as substrate by Lineweaver-Burk plot based Michelis-Menten e... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116187 BindingDB Entry DOI: 10.7270/Q2SN0DQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115974 (CHEMBL3612170) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115973 (CHEMBL3612151) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 137 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant DAT | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115978 (CHEMBL3612172) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115977 (CHEMBL3612153) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115972 (CHEMBL3612169) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115971 (CHEMBL3612150) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 336 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M5 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 351 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M4 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 415 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M4 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 432 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant 5HT1A receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 437 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M5 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 462 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M2 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115976 (CHEMBL3612171) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115975 (CHEMBL3612152) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116014 (CHEMBL3612160) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116013 (CHEMBL3612141) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 512 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M3 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 681 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M2 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115962 (CHEMBL3612149) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115968 (CHEMBL3612168) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM66082 ((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | 880 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human full length N-terminal His-tagged ATIC expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in THF formatio... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116093 BindingDB Entry DOI: 10.7270/Q2RF5ZQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 923 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant H2 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 931 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant M1 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116015 (CHEMBL3612142) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116016 (CHEMBL3612161) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115960 (CHEMBL3612148) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115961 (CHEMBL3612167) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional purine biosynthesis protein ATIC (Homo sapiens (Human)) | BDBM50557564 (CHEMBL4783397) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human full length N-terminal His-tagged ATIC expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in THF formatio... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116093 BindingDB Entry DOI: 10.7270/Q2RF5ZQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115980 (CHEMBL3612173) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115979 (CHEMBL3612154) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50383117 (CHEMBL2031737) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant 5HT2A receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Homo sapiens (Human)) | BDBM50158610 ((4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health Curated by ChEMBL | Assay Description Binding affinity to human recombinant H2 receptor | J Med Chem 55: 2406-15 (2012) Article DOI: 10.1021/jm201690h BindingDB Entry DOI: 10.7270/Q2BR8T6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115829 (CHEMBL3612139) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50115958 (CHEMBL3612158) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116022 (CHEMBL3612164) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116021 (CHEMBL3612145) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116069 (CHEMBL3612147) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116060 (CHEMBL3612165) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | >2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50116023 (CHEMBL3612146) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL | Assay Description Inhibition of P-glycoprotein in human drug-resistant K562/ADR cells assessed as reduction in P-gp mediated rhodamine 123 efflux by spectrofluorometry | Eur J Med Chem 101: 126-32 (2015) Article DOI: 10.1016/j.ejmech.2015.06.002 BindingDB Entry DOI: 10.7270/Q2PN97FH | |||||||||||
More data for this Ligand-Target Pair |
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