Compile Data Set for Download or QSAR

Found 70 hits with Last Name = 'albaugh' and Initial = 'dr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin G (Homo sapiens (Human))	BDBM50349174 (CHEMBL1807526) Show SMILES Cc1cccc2scc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C20H18N2O3S/c1-13-5-4-8-17-19(13)14(12-26-17)11-22-16-7-3-2-6-15(16)21(20(22)25)10-9-18(23)24/h2-8,12H,9-11H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349176 (CHEMBL1807531) Show SMILES Cc1cccc2n(C)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H21N3O3/c1-14-6-5-9-18-20(14)15(12-22(18)2)13-24-17-8-4-3-7-16(17)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349173 (CHEMBL1807638) Show SMILES Cc1c(C)c2cc(C)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C23H25N3O3/c1-14-11-17(22-18(12-14)15(2)16(3)24(22)4)13-26-20-8-6-5-7-19(20)25(23(26)29)10-9-21(27)28/h5-8,11-12H,9-10,13H2,1-4H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349183 (CHEMBL1807538) Show SMILES Cc1cn(C)c2c(Cn3c4ccccc4n(CCC(O)=O)c3=O)cccc12 Show InChI InChI=1S/C21H21N3O3/c1-14-12-22(2)20-15(6-5-7-16(14)20)13-24-18-9-4-3-8-17(18)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349178 (CHEMBL1807535) Show SMILES Cc1cc(C)c2c(Cn3c4ccccc4n(CCC(O)=O)c3=O)nsc2c1 Show InChI InChI=1S/C20H19N3O3S/c1-12-9-13(2)19-14(21-27-17(19)10-12)11-23-16-6-4-3-5-15(16)22(20(23)26)8-7-18(24)25/h3-6,9-10H,7-8,11H2,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349182 (CHEMBL1807534) Show SMILES Cc1cccc2c(cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)n12)C#N Show InChI InChI=1S/C21H18N4O3/c1-14-5-4-8-17-15(12-22)11-16(25(14)17)13-24-19-7-3-2-6-18(19)23(21(24)28)10-9-20(26)27/h2-8,11H,9-10,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349181 (CHEMBL1807536) Show SMILES Cn1ccc2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C20H19N3O3/c1-21-11-9-14-5-4-6-15(19(14)21)13-23-17-8-3-2-7-16(17)22(20(23)26)12-10-18(24)25/h2-9,11H,10,12-13H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349179 (CHEMBL1807537) Show SMILES Cc1cc2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C21H21N3O3/c1-14-12-15-6-5-7-16(20(15)22(14)2)13-24-18-9-4-3-8-17(18)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349186 (CHEMBL1807539) Show SMILES Cc1cn(C)c2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H21N3O3/c1-14-12-22(2)18-9-5-6-15(20(14)18)13-24-17-8-4-3-7-16(17)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349175 (CHEMBL1807637) Show SMILES Cc1c(C)c2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C22H23N3O3/c1-14-15(2)23(3)21-16(7-6-8-17(14)21)13-25-19-10-5-4-9-18(19)24(22(25)28)12-11-20(26)27/h4-10H,11-13H2,1-3H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349177 (CHEMBL1807639) Show SMILES COc1cc(Cn2c3ccccc3n(CCC(O)=O)c2=O)c2n(C)c(C)c(C)c2c1 Show InChI InChI=1S/C23H25N3O4/c1-14-15(2)24(3)22-16(11-17(30-4)12-18(14)22)13-26-20-8-6-5-7-19(20)25(23(26)29)10-9-21(27)28/h5-8,11-12H,9-10,13H2,1-4H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349190 (CHEMBL1807641) Show SMILES Cc1c(C)c2ccc(Cl)c(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C22H22ClN3O3/c1-13-14(2)24(3)21-15(13)8-9-17(23)16(21)12-26-19-7-5-4-6-18(19)25(22(26)29)11-10-20(27)28/h4-9H,10-12H2,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349189 (CHEMBL1807533) Show SMILES Cc1cccn2ncc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C19H18N4O3/c1-13-5-4-9-23-18(13)14(11-20-23)12-22-16-7-3-2-6-15(16)21(19(22)26)10-8-17(24)25/h2-7,9,11H,8,10,12H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349188 (CHEMBL1807532) Show SMILES Cc1cccc2ncc(Cn3c4ccccc4n(CCC(O)=O)c3=O)n12 Show InChI InChI=1S/C19H18N4O3/c1-13-5-4-8-17-20-11-14(23(13)17)12-22-16-7-3-2-6-15(16)21(19(22)26)10-9-18(24)25/h2-8,11H,9-10,12H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349180 (CHEMBL1807530) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2cccc3ccccc23)c1=O Show InChI InChI=1S/C21H18N2O3/c24-20(25)12-13-22-18-10-3-4-11-19(18)23(21(22)26)14-16-8-5-7-15-6-1-2-9-17(15)16/h1-11H,12-14H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349185 (CHEMBL1807529) Show SMILES Cn1cc(Cn2c3ccccc3n(CCC(O)=O)c2=O)c2ccccc12 Show InChI InChI=1S/C20H19N3O3/c1-21-12-14(15-6-2-3-7-16(15)21)13-23-18-9-5-4-8-17(18)22(20(23)26)11-10-19(24)25/h2-9,12H,10-11,13H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349184 (CHEMBL1807527) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2csc3ccccc23)c1=O Show InChI InChI=1S/C19H16N2O3S/c22-18(23)9-10-20-15-6-2-3-7-16(15)21(19(20)24)11-13-12-25-17-8-4-1-5-14(13)17/h1-8,12H,9-11H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349187 (CHEMBL1807528) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2nsc3ccccc23)c1=O Show InChI InChI=1S/C18H15N3O3S/c22-17(23)9-10-20-14-6-2-3-7-15(14)21(18(20)24)11-13-12-5-1-4-8-16(12)25-19-13/h1-8H,9-11H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349191 (CHEMBL1807642) Show SMILES Cc1cccc2scc(Cn3c(SCCCC(O)=O)nc4ccccc34)c12 Show InChI InChI=1S/C21H20N2O2S2/c1-14-6-4-9-18-20(14)15(13-27-18)12-23-17-8-3-2-7-16(17)22-21(23)26-11-5-10-19(24)25/h2-4,6-9,13H,5,10-12H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cathepsin G (Homo sapiens (Human))	BDBM50349172 (CHEMBL1807640) Show SMILES Cc1c(C)c2cc(Cl)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C22H22ClN3O3/c1-13-14(2)24(3)21-15(10-16(23)11-17(13)21)12-26-19-7-5-4-6-18(19)25(22(26)29)9-8-20(27)28/h4-7,10-11H,8-9,12H2,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349172 (CHEMBL1807640) Show SMILES Cc1c(C)c2cc(Cl)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C22H22ClN3O3/c1-13-14(2)24(3)21-15(10-16(23)11-17(13)21)12-26-19-7-5-4-6-18(19)25(22(26)29)9-8-20(27)28/h4-7,10-11H,8-9,12H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434109 (CHEMBL2381483) Show SMILES CCCC(CC(O)=O)n1c2ccccc2n(Cc2cc(Br)cc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C22H22BrN3O4/c1-2-5-15(10-21(28)29)26-19-7-4-3-6-18(19)25(22(26)30)12-13-8-14(23)9-17-16(13)11-20(27)24-17/h3-4,6-9,15H,2,5,10-12H2,1H3,(H,24,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Chymase (Homo sapiens (Human))	BDBM50434124 (CHEMBL2381480) Show SMILES CCCC(Cn1c2ccccc2n(Cc2cc(Br)cc3[nH]c(=O)sc23)c1=O)C(O)=O Show InChI InChI=1S/C21H20BrN3O4S/c1-2-5-12(19(26)27)10-24-16-6-3-4-7-17(16)25(21(24)29)11-13-8-14(22)9-15-18(13)30-20(28)23-15/h3-4,6-9,12H,2,5,10-11H2,1H3,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349191 (CHEMBL1807642) Show SMILES Cc1cccc2scc(Cn3c(SCCCC(O)=O)nc4ccccc34)c12 Show InChI InChI=1S/C21H20N2O2S2/c1-14-6-4-9-18-20(14)15(13-27-18)12-23-17-8-3-2-7-16(17)22-21(23)26-11-5-10-19(24)25/h2-4,6-9,13H,5,10-12H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434108 (CHEMBL2381482) Show SMILES CCCC(Cn1c2ccccc2n(Cc2cc(Br)cc3NC(=O)Cc23)c1=O)C(O)=O Show InChI InChI=1S/C22H22BrN3O4/c1-2-5-13(21(28)29)11-25-18-6-3-4-7-19(18)26(22(25)30)12-14-8-15(23)9-17-16(14)10-20(27)24-17/h3-4,6-9,13H,2,5,10-12H2,1H3,(H,24,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349173 (CHEMBL1807638) Show SMILES Cc1c(C)c2cc(C)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C23H25N3O3/c1-14-11-17(22-18(12-14)15(2)16(3)24(22)4)13-26-20-8-6-5-7-19(20)25(23(26)29)10-9-21(27)28/h5-8,11-12H,9-10,13H2,1-4H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349174 (CHEMBL1807526) Show SMILES Cc1cccc2scc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C20H18N2O3S/c1-13-5-4-8-17-19(13)14(12-26-17)11-22-16-7-3-2-6-15(16)21(20(22)25)10-9-18(23)24/h2-8,12H,9-11H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349192 (CHEMBL1807643) Show SMILES Cc1cccc2scc(Cn3c4ccccc4n(CCCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H20N2O3S/c1-14-6-4-9-18-20(14)15(13-27-18)12-23-17-8-3-2-7-16(17)22(21(23)26)11-5-10-19(24)25/h2-4,6-9,13H,5,10-12H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Chymase (Homo sapiens (Human))	BDBM50349175 (CHEMBL1807637) Show SMILES Cc1c(C)c2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C22H23N3O3/c1-14-15(2)23(3)21-16(7-6-8-17(14)21)13-25-19-10-5-4-9-18(19)24(22(25)28)12-11-20(26)27/h4-10H,11-13H2,1-3H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349176 (CHEMBL1807531) Show SMILES Cc1cccc2n(C)cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H21N3O3/c1-14-6-5-9-18-20(14)15(12-22(18)2)13-24-17-8-4-3-7-16(17)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349192 (CHEMBL1807643) Show SMILES Cc1cccc2scc(Cn3c4ccccc4n(CCCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H20N2O3S/c1-14-6-4-9-18-20(14)15(13-27-18)12-23-17-8-3-2-7-16(17)22(21(23)26)11-5-10-19(24)25/h2-4,6-9,13H,5,10-12H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Chymase (Homo sapiens (Human))	BDBM50349177 (CHEMBL1807639) Show SMILES COc1cc(Cn2c3ccccc3n(CCC(O)=O)c2=O)c2n(C)c(C)c(C)c2c1 Show InChI InChI=1S/C23H25N3O4/c1-14-15(2)24(3)22-16(11-17(30-4)12-18(14)22)13-26-20-8-6-5-7-19(20)25(23(26)29)10-9-21(27)28/h5-8,11-12H,9-10,13H2,1-4H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434110 (CHEMBL2381484) Show SMILES CCCC(CC(O)=O)n1c2ccccc2n(Cc2cc(Cl)cc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C22H22ClN3O4/c1-2-5-15(10-21(28)29)26-19-7-4-3-6-18(19)25(22(26)30)12-13-8-14(23)9-17-16(13)11-20(27)24-17/h3-4,6-9,15H,2,5,10-12H2,1H3,(H,24,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349178 (CHEMBL1807535) Show SMILES Cc1cc(C)c2c(Cn3c4ccccc4n(CCC(O)=O)c3=O)nsc2c1 Show InChI InChI=1S/C20H19N3O3S/c1-12-9-13(2)19-14(21-27-17(19)10-12)11-23-16-6-4-3-5-15(16)22(20(23)26)8-7-18(24)25/h3-6,9-10H,7-8,11H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349179 (CHEMBL1807537) Show SMILES Cc1cc2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c2n1C Show InChI InChI=1S/C21H21N3O3/c1-14-12-15-6-5-7-16(20(15)22(14)2)13-24-18-9-4-3-8-17(18)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349180 (CHEMBL1807530) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2cccc3ccccc23)c1=O Show InChI InChI=1S/C21H18N2O3/c24-20(25)12-13-22-18-10-3-4-11-19(18)23(21(22)26)14-16-8-5-7-15-6-1-2-9-17(15)16/h1-11H,12-14H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349181 (CHEMBL1807536) Show SMILES Cn1ccc2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C20H19N3O3/c1-21-11-9-14-5-4-6-15(19(14)21)13-23-17-8-3-2-7-16(17)22(20(23)26)12-10-18(24)25/h2-9,11H,10,12-13H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349182 (CHEMBL1807534) Show SMILES Cc1cccc2c(cc(Cn3c4ccccc4n(CCC(O)=O)c3=O)n12)C#N Show InChI InChI=1S/C21H18N4O3/c1-14-5-4-8-17-15(12-22)11-16(25(14)17)13-24-19-7-3-2-6-18(19)23(21(24)28)10-9-20(26)27/h2-8,11H,9-10,13H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349183 (CHEMBL1807538) Show SMILES Cc1cn(C)c2c(Cn3c4ccccc4n(CCC(O)=O)c3=O)cccc12 Show InChI InChI=1S/C21H21N3O3/c1-14-12-22(2)20-15(6-5-7-16(14)20)13-24-18-9-4-3-8-17(18)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434107 (CHEMBL2381481) Show SMILES CCCC(CC(O)=O)n1c2ccccc2n(Cc2cccc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C22H23N3O4/c1-2-6-15(11-21(27)28)25-19-10-4-3-9-18(19)24(22(25)29)13-14-7-5-8-17-16(14)12-20(26)23-17/h3-5,7-10,15H,2,6,11-13H2,1H3,(H,23,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50349192 (CHEMBL1807643) Show SMILES Cc1cccc2scc(Cn3c4ccccc4n(CCCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H20N2O3S/c1-14-6-4-9-18-20(14)15(13-27-18)12-23-17-8-3-2-7-16(17)22(21(23)26)11-5-10-19(24)25/h2-4,6-9,13H,5,10-12H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434123 (CHEMBL2381479) Show SMILES OC(=O)CCCSc1nc2ccccc2n1Cc1cc(Cl)cc2NC(=O)Cc12 Show InChI InChI=1S/C20H18ClN3O3S/c21-13-8-12(14-10-18(25)22-16(14)9-13)11-24-17-5-2-1-4-15(17)23-20(24)28-7-3-6-19(26)27/h1-2,4-5,8-9H,3,6-7,10-11H2,(H,22,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349184 (CHEMBL1807527) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2csc3ccccc23)c1=O Show InChI InChI=1S/C19H16N2O3S/c22-18(23)9-10-20-15-6-2-3-7-16(15)21(19(20)24)11-13-12-25-17-8-4-1-5-14(13)17/h1-8,12H,9-11H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434111 (CHEMBL2381485) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2cc(Br)cc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C19H16BrN3O4/c20-12-7-11(13-9-17(24)21-14(13)8-12)10-23-16-4-2-1-3-15(16)22(19(23)27)6-5-18(25)26/h1-4,7-8H,5-6,9-10H2,(H,21,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349185 (CHEMBL1807529) Show SMILES Cn1cc(Cn2c3ccccc3n(CCC(O)=O)c2=O)c2ccccc12 Show InChI InChI=1S/C20H19N3O3/c1-21-12-14(15-6-2-3-7-16(15)21)13-23-18-9-5-4-8-17(18)22(20(23)26)11-10-19(24)25/h2-9,12H,10-11,13H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349186 (CHEMBL1807539) Show SMILES Cc1cn(C)c2cccc(Cn3c4ccccc4n(CCC(O)=O)c3=O)c12 Show InChI InChI=1S/C21H21N3O3/c1-14-12-22(2)18-9-5-6-15(20(14)18)13-24-17-8-4-3-7-16(17)23(21(24)27)11-10-19(25)26/h3-9,12H,10-11,13H2,1-2H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50434112 (CHEMBL2381487) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2cc(Cl)cc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C19H16ClN3O4/c20-12-7-11(13-9-17(24)21-14(13)8-12)10-23-16-4-2-1-3-15(16)22(19(23)27)6-5-18(25)26/h1-4,7-8H,5-6,9-10H2,(H,21,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50434123 (CHEMBL2381479) Show SMILES OC(=O)CCCSc1nc2ccccc2n1Cc1cc(Cl)cc2NC(=O)Cc12 Show InChI InChI=1S/C20H18ClN3O3S/c21-13-8-12(14-10-18(25)22-16(14)9-13)11-24-17-5-2-1-4-15(17)23-20(24)28-7-3-6-19(26)27/h1-2,4-5,8-9H,3,6-7,10-11H2,(H,22,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50349187 (CHEMBL1807528) Show SMILES OC(=O)CCn1c2ccccc2n(Cc2nsc3ccccc23)c1=O Show InChI InChI=1S/C18H15N3O3S/c22-17(23)9-10-20-14-6-2-3-7-15(14)21(18(20)24)11-13-12-5-1-4-8-16(12)25-19-13/h1-8H,9-11H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human chymase after 1 hr by fluorometric assay				Bioorg Med Chem Lett 21: 4533-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.126 BindingDB Entry DOI: 10.7270/Q23B60H0
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50434109 (CHEMBL2381483) Show SMILES CCCC(CC(O)=O)n1c2ccccc2n(Cc2cc(Br)cc3NC(=O)Cc23)c1=O Show InChI InChI=1S/C22H22BrN3O4/c1-2-5-15(10-21(28)29)26-19-7-4-3-6-18(19)25(22(26)30)12-13-8-14(23)9-17-16(13)11-20(27)24-17/h3-4,6-9,15H,2,5,10-12H2,1H3,(H,24,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay				J Med Chem 56: 4465-81 (2013) Article DOI: 10.1021/jm400138z BindingDB Entry DOI: 10.7270/Q2C82BPN
					More data for this Ligand-Target Pair

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