Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'berlove' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50344821 (10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...) Show SMILES NC1=N[C@H](O)[C@H]2[C@H]3O[C@]4(O)O[C@@H]([C@@H](O)[C@@]2(N1)[C@@H]4O)[C@]3(O)CO |r,t:1,TLB:13:12:16:6.7.5,18:11:16:6.7.5,18:6:16:11.10.12,19:18:7:16.14.5,20:18:7:16.14.5,THB:12:11:7:16.14.5,3:5:16:11.10.12| Show InChI InChI=1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2-,3-,4-,5+,6-,7+,9+,10-,11+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066059 (1,3-Bis-(4-sec-butyl-phenyl)-tetrahydro-pyrimidin-...) Show SMILES CCC(C)c1ccc(cc1)N1CCCN(C1=N)c1ccc(cc1)C(C)CC Show InChI InChI=1S/C24H33N3/c1-5-18(3)20-8-12-22(13-9-20)26-16-7-17-27(24(26)25)23-14-10-21(11-15-23)19(4)6-2/h8-15,18-19,25H,5-7,16-17H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066062 (1,3-Bis-(4-sec-butyl-phenyl)-imidazolidin-2-yliden...) Show SMILES CCC(C)c1ccc(cc1)N1CCN(C1=N)c1ccc(cc1)C(C)CC Show InChI InChI=1S/C23H31N3/c1-5-17(3)19-7-11-21(12-8-19)25-15-16-26(23(25)24)22-13-9-20(10-14-22)18(4)6-2/h7-14,17-18,24H,5-6,15-16H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066417 (CHEMBL112806 | N-(4-Benzyloxy-phenyl)-N'-(4-tert-b...) Show SMILES CC(C)(C)c1ccc(NC(N)=Nc2ccc(OCc3ccccc3)cc2)cc1 |w:11.11| Show InChI InChI=1S/C24H27N3O/c1-24(2,3)19-9-11-20(12-10-19)26-23(25)27-21-13-15-22(16-14-21)28-17-18-7-5-4-6-8-18/h4-16H,17H2,1-3H3,(H3,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066427 (CHEMBL109210 | N,N'-Bis-(4-butyl-phenyl)-guanidine) Show SMILES CCCCc1ccc(NC(N)=Nc2ccc(CCCC)cc2)cc1 |w:11.11| Show InChI InChI=1S/C21H29N3/c1-3-5-7-17-9-13-19(14-10-17)23-21(22)24-20-15-11-18(12-16-20)8-6-4-2/h9-16H,3-8H2,1-2H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066420 (CHEMBL112132 | N-(4-Benzyloxy-phenyl)-N'-(4-butyl-...) Show SMILES CCCCc1ccc(NC(N)=Nc2ccc(OCc3ccccc3)cc2)cc1 |w:11.11| Show InChI InChI=1S/C24H27N3O/c1-2-3-7-19-10-12-21(13-11-19)26-24(25)27-22-14-16-23(17-15-22)28-18-20-8-5-4-6-9-20/h4-6,8-17H,2-3,7,18H2,1H3,(H3,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066423 (CHEMBL326502 | N,N'-Bis-(4-butoxy-phenyl)-guanidin...) Show SMILES CCCCOc1ccc(NC(N)=Nc2ccc(OCCCC)cc2)cc1 |w:12.12| Show InChI InChI=1S/C21H29N3O2/c1-3-5-15-25-19-11-7-17(8-12-19)23-21(22)24-18-9-13-20(14-10-18)26-16-6-4-2/h7-14H,3-6,15-16H2,1-2H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066066 ((S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidi...) Show SMILES CN(C1CCN(C[C@H](O)COc2ccc(F)c(F)c2)CC1)c1nc2ccccc2s1 Show InChI InChI=1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066425 (CHEMBL112515 | N,N'-Bis-(4-phenoxy-phenyl)-guanidi...) Show SMILES NC(Nc1ccc(Oc2ccccc2)cc1)=Nc1ccc(Oc2ccccc2)cc1 |w:16.18| Show InChI InChI=1S/C25H21N3O2/c26-25(27-19-11-15-23(16-12-19)29-21-7-3-1-4-8-21)28-20-13-17-24(18-14-20)30-22-9-5-2-6-10-22/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066067 (2-(4-tert-Butyl-phenyl)-6-isopropyl-3,4-dihydro-2H...) Show SMILES CC(C)c1ccc2N(C(CCc2c1)c1ccc(cc1)C(C)(C)C)C(N)=N Show InChI InChI=1S/C23H31N3/c1-15(2)17-8-12-21-18(14-17)9-13-20(26(21)22(24)25)16-6-10-19(11-7-16)23(3,4)5/h6-8,10-12,14-15,20H,9,13H2,1-5H3,(H3,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50010754 (CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...) Show SMILES CC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)C)cc1 |w:10.10| Show InChI InChI=1S/C19H25N3/c1-13(2)15-5-9-17(10-6-15)21-19(20)22-18-11-7-16(8-12-18)14(3)4/h5-14H,1-4H3,(H3,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107034 (CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...) Show SMILES CCCCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:16.17| Show InChI InChI=1S/C22H29N3O2/c1-2-3-17-27-20-14-12-19(13-15-20)21(26)25-22(23)24-16-8-7-11-18-9-5-4-6-10-18/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H3,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066069 (CHEMBL103284 | N-(4-tert-Butyl-benzyl)-N-(4-sec-bu...) Show SMILES CCC(C)c1ccc(cc1)N(Cc1ccc(cc1)C(C)(C)C)C(N)=N Show InChI InChI=1S/C22H31N3/c1-6-16(2)18-9-13-20(14-10-18)25(21(23)24)15-17-7-11-19(12-8-17)22(3,4)5/h7-14,16H,6,15H2,1-5H3,(H3,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107034 (CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...) Show SMILES CCCCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:16.17| Show InChI InChI=1S/C22H29N3O2/c1-2-3-17-27-20-14-12-19(13-15-20)21(26)25-22(23)24-16-8-7-11-18-9-5-4-6-10-18/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H3,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066428 (CHEMBL326774 | N-Acenaphthen-5-yl-N'-(4-sec-butyl-...) Show SMILES CCC(C)c1ccc(NC(N)=Nc2ccc3CCc4cccc2c34)cc1 |w:11.11| Show InChI InChI=1S/C23H25N3/c1-3-15(2)16-9-12-19(13-10-16)25-23(24)26-21-14-11-18-8-7-17-5-4-6-20(21)22(17)18/h4-6,9-15H,3,7-8H2,1-2H3,(H3,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107029 (CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...) Show SMILES CCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:14.15| Show InChI InChI=1S/C20H25N3O2/c1-2-25-18-13-11-17(12-14-18)19(24)23-20(21)22-15-7-6-10-16-8-4-3-5-9-16/h3-5,8-9,11-14H,2,6-7,10,15H2,1H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066052 ((3-sec-Butyl-phenyl)-[1-(4-sec-butyl-phenyl)-imida...) Show SMILES CCC(C)c1ccc(cc1)N1CCNC1=Nc1cccc(c1)C(C)CC |w:15.17| Show InChI InChI=1S/C23H31N3/c1-5-17(3)19-10-12-22(13-11-19)26-15-14-24-23(26)25-21-9-7-8-20(16-21)18(4)6-2/h7-13,16-18H,5-6,14-15H2,1-4H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066057 (CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...) Show SMILES CCC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)CC)cc1 |w:11.11| Show InChI InChI=1S/C21H29N3/c1-5-15(3)17-7-11-19(12-8-17)23-21(22)24-20-13-9-18(10-14-20)16(4)6-2/h7-16H,5-6H2,1-4H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066057 (CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...) Show SMILES CCC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)CC)cc1 |w:11.11| Show InChI InChI=1S/C21H29N3/c1-5-15(3)17-7-11-19(12-8-17)23-21(22)24-20-13-9-18(10-14-20)16(4)6-2/h7-16H,5-6H2,1-4H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107043 (CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...) Show SMILES COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:13.14| Show InChI InChI=1S/C19H23N3O2/c1-24-17-12-10-16(11-13-17)18(23)22-19(20)21-14-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066419 (CHEMBL326741 | N,N'-Bis-(4-hexyl-phenyl)-guanidine) Show SMILES CCCCCCc1ccc(NC(N)=Nc2ccc(CCCCCC)cc2)cc1 |w:13.13| Show InChI InChI=1S/C25H37N3/c1-3-5-7-9-11-21-13-17-23(18-14-21)27-25(26)28-24-19-15-22(16-20-24)12-10-8-6-4-2/h13-20H,3-12H2,1-2H3,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066424 (CHEMBL331126 | N,N'-Bis-(4-phenylsulfanyl-phenyl)-...) Show SMILES NC(Nc1ccc(Sc2ccccc2)cc1)=Nc1ccc(Sc2ccccc2)cc1 |w:16.18| Show InChI InChI=1S/C25H21N3S2/c26-25(27-19-11-15-23(16-12-19)29-21-7-3-1-4-8-21)28-20-13-17-24(18-14-20)30-22-9-5-2-6-10-22/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066422 (CHEMBL326130 | N,N'-Bis-biphenyl-4-yl-guanidine) Show SMILES NC(Nc1ccc(cc1)-c1ccccc1)=Nc1ccc(cc1)-c1ccccc1 |w:15.17| Show InChI InChI=1S/C25H21N3/c26-25(27-23-15-11-21(12-16-23)19-7-3-1-4-8-19)28-24-17-13-22(14-18-24)20-9-5-2-6-10-20/h1-18H,(H3,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107032 (CHEMBL110572 | N-(Naphthalene-1-carbonyl)-N'-(4-ph...) Show SMILES NC(NC(=O)c1cccc2ccccc12)=NCCCCc1ccccc1 |w:15.17| Show InChI InChI=1S/C22H23N3O/c23-22(24-16-7-6-11-17-9-2-1-3-10-17)25-21(26)20-15-8-13-18-12-4-5-14-19(18)20/h1-5,8-10,12-15H,6-7,11,16H2,(H3,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066060 (CHEMBL545504 | N,N'-Bis-(4-sec-butyl-phenyl)-N,N'-...) Show SMILES CCC(C)c1ccc(cc1)N(C)C(=N)N(C)c1ccc(cc1)C(C)CC Show InChI InChI=1S/C23H33N3/c1-7-17(3)19-9-13-21(14-10-19)25(5)23(24)26(6)22-15-11-20(12-16-22)18(4)8-2/h9-18,24H,7-8H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107029 (CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...) Show SMILES CCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:14.15| Show InChI InChI=1S/C20H25N3O2/c1-2-25-18-13-11-17(12-14-18)19(24)23-20(21)22-15-7-6-10-16-8-4-3-5-9-16/h3-5,8-9,11-14H,2,6-7,10,15H2,1H3,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107031 (CHEMBL108728 | N-(4-Methyl-benzoyl)-N'-(4-phenyl-b...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:12.13| Show InChI InChI=1S/C19H23N3O/c1-15-10-12-17(13-11-15)18(23)22-19(20)21-14-6-5-9-16-7-3-2-4-8-16/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107030 (CHEMBL106459 | N-(2-Methyl-benzoyl)-N'-(4-phenyl-b...) Show SMILES Cc1ccccc1C(=O)NC(N)=NCCCCc1ccccc1 |w:12.13| Show InChI InChI=1S/C19H23N3O/c1-15-9-5-6-13-17(15)18(23)22-19(20)21-14-8-7-12-16-10-3-2-4-11-16/h2-6,9-11,13H,7-8,12,14H2,1H3,(H3,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50010736 (CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine) Show SMILES CCc1ccc(NC(N)=Nc2ccc(CC)cc2)cc1 |w:9.9| Show InChI InChI=1S/C17H21N3/c1-3-13-5-9-15(10-6-13)19-17(18)20-16-11-7-14(4-2)8-12-16/h5-12H,3-4H2,1-2H3,(H3,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107046 (CHEMBL110164 | N-(4-Phenyl-butyl)-N'-(3,4,5-trimet...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC(N)=NCCCCc1ccccc1 |w:17.18| Show InChI InChI=1S/C21H27N3O4/c1-26-17-13-16(14-18(27-2)19(17)28-3)20(25)24-21(22)23-12-8-7-11-15-9-5-4-6-10-15/h4-6,9-10,13-14H,7-8,11-12H2,1-3H3,(H3,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107039 (CHEMBL109012 | N-(2,3-Dichloro-benzoyl)-N'-(4-phen...) Show SMILES NC(NC(=O)c1cccc(Cl)c1Cl)=NCCCCc1ccccc1 |w:13.14| Show InChI InChI=1S/C18H19Cl2N3O/c19-15-11-6-10-14(16(15)20)17(24)23-18(21)22-12-5-4-9-13-7-2-1-3-8-13/h1-3,6-8,10-11H,4-5,9,12H2,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107046 (CHEMBL110164 | N-(4-Phenyl-butyl)-N'-(3,4,5-trimet...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC(N)=NCCCCc1ccccc1 |w:17.18| Show InChI InChI=1S/C21H27N3O4/c1-26-17-13-16(14-18(27-2)19(17)28-3)20(25)24-21(22)23-12-8-7-11-15-9-5-4-6-10-15/h4-6,9-10,13-14H,7-8,11-12H2,1-3H3,(H3,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066421 (CHEMBL320340 | N,N'-Bis-(4-tert-butyl-phenyl)-guan...) Show SMILES CC(C)(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)(C)C)cc1 |w:11.11| Show InChI InChI=1S/C21H29N3/c1-20(2,3)15-7-11-17(12-8-15)23-19(22)24-18-13-9-16(10-14-18)21(4,5)6/h7-14H,1-6H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066068 (CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...) Show SMILES COc1ccc(N=C(N)Nc2ccc3CCc4cccc2c34)c2ccccc12 |w:6.5| Show InChI InChI=1S/C24H21N3O/c1-28-22-14-13-20(17-6-2-3-7-18(17)22)26-24(25)27-21-12-11-16-10-9-15-5-4-8-19(21)23(15)16/h2-8,11-14H,9-10H2,1H3,(H3,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066068 (CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...) Show SMILES COc1ccc(N=C(N)Nc2ccc3CCc4cccc2c34)c2ccccc12 |w:6.5| Show InChI InChI=1S/C24H21N3O/c1-28-22-14-13-20(17-6-2-3-7-18(17)22)26-24(25)27-21-12-11-16-10-9-15-5-4-8-19(21)23(15)16/h2-8,11-14H,9-10H2,1H3,(H3,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107030 (CHEMBL106459 | N-(2-Methyl-benzoyl)-N'-(4-phenyl-b...) Show SMILES Cc1ccccc1C(=O)NC(N)=NCCCCc1ccccc1 |w:12.13| Show InChI InChI=1S/C19H23N3O/c1-15-9-5-6-13-17(15)18(23)22-19(20)21-14-8-7-12-16-10-3-2-4-11-16/h2-6,9-11,13H,7-8,12,14H2,1H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107045 (CHEMBL421032 | N-[2-(5-Methoxy-1H-indol-3-yl)-ethy...) Show SMILES COc1ccc2[nH]cc(CCN=C(N)NC(=O)c3ccc(C)cc3)c2c1 |w:11.10| Show InChI InChI=1S/C20H22N4O2/c1-13-3-5-14(6-4-13)19(25)24-20(21)22-10-9-15-12-23-18-8-7-16(26-2)11-17(15)18/h3-8,11-12,23H,9-10H2,1-2H3,(H3,21,22,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107045 (CHEMBL421032 | N-[2-(5-Methoxy-1H-indol-3-yl)-ethy...) Show SMILES COc1ccc2[nH]cc(CCN=C(N)NC(=O)c3ccc(C)cc3)c2c1 |w:11.10| Show InChI InChI=1S/C20H22N4O2/c1-13-3-5-14(6-4-13)19(25)24-20(21)22-10-9-15-12-23-18-8-7-16(26-2)11-17(15)18/h3-8,11-12,23H,9-10H2,1-2H3,(H3,21,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066429 (CHEMBL325215 | N-(4-Butoxy-phenyl)-N'-[4-(4-hydrox...) Show SMILES CCCCOc1ccc(cc1)N=C(N)Nc1ccc(CCCCO)cc1 |w:11.11| Show InChI InChI=1S/C21H29N3O2/c1-2-3-16-26-20-13-11-19(12-14-20)24-21(22)23-18-9-7-17(8-10-18)6-4-5-15-25/h7-14,25H,2-6,15-16H2,1H3,(H3,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066061 (1-(4-sec-Butyl-phenyl)-5-(4-isopropyl-phenyl)-imid...) Show SMILES CCC(C)c1ccc(cc1)N1C(CN=C1N)c1ccc(cc1)C(C)C |c:14| Show InChI InChI=1S/C22H29N3/c1-5-16(4)18-10-12-20(13-11-18)25-21(14-24-22(25)23)19-8-6-17(7-9-19)15(2)3/h6-13,15-16,21H,5,14H2,1-4H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience Inc. Curated by ChEMBL					Assay Description In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)				J Med Chem 41: 3048-61 (1998) Article DOI: 10.1021/jm980124a BindingDB Entry DOI: 10.7270/Q2R49RF5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107020 (CHEMBL105782 | N-(4-Methyl-benzoyl)-N'-(3,4,5-trim...) Show SMILES COc1cc(cc(OC)c1OC)N=C(N)NC(=O)c1ccc(C)cc1 |w:12.12| Show InChI InChI=1S/C18H21N3O4/c1-11-5-7-12(8-6-11)17(22)21-18(19)20-13-9-14(23-2)16(25-4)15(10-13)24-3/h5-10H,1-4H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107050 (CHEMBL107394 | N-(4-Isopropyl-phenyl)-N'-(4-methyl...) Show SMILES CC(C)c1ccc(cc1)N=C(N)NC(=O)c1ccc(C)cc1 |w:9.9| Show InChI InChI=1S/C18H21N3O/c1-12(2)14-8-10-16(11-9-14)20-18(19)21-17(22)15-6-4-13(3)5-7-15/h4-12H,1-3H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107035 (CHEMBL320332 | N-[2-(4-Chloro-phenyl)-ethyl]-N'-(4...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCCc1ccc(Cl)cc1 |w:12.13| Show InChI InChI=1S/C17H18ClN3O/c1-12-2-6-14(7-3-12)16(22)21-17(19)20-11-10-13-4-8-15(18)9-5-13/h2-9H,10-11H2,1H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107025 (CHEMBL106351 | N-(4-Isopropoxy-phenyl)-N'-(4-methy...) Show SMILES CC(C)Oc1ccc(cc1)N=C(N)NC(=O)c1ccc(C)cc1 |w:10.10| Show InChI InChI=1S/C18H21N3O2/c1-12(2)23-16-10-8-15(9-11-16)20-18(19)21-17(22)14-6-4-13(3)5-7-14/h4-12H,1-3H3,(H3,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107043 (CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...) Show SMILES COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:13.14| Show InChI InChI=1S/C19H23N3O2/c1-24-17-12-10-16(11-13-17)18(23)22-19(20)21-14-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107037 (CHEMBL106610 | N-(4-Methyl-benzoyl)-N'-(5-phenyl-p...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCCCCCc1ccccc1 |w:12.13| Show InChI InChI=1S/C20H25N3O/c1-16-11-13-18(14-12-16)19(24)23-20(21)22-15-7-3-6-10-17-8-4-2-5-9-17/h2,4-5,8-9,11-14H,3,6-7,10,15H2,1H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50107038 (CHEMBL108361 | N-(4-Phenyl-butyl)-N'-(thiophene-2-...) Show SMILES NC(NC(=O)c1cccs1)=NCCCCc1ccccc1 |w:10.11| Show InChI InChI=1S/C16H19N3OS/c17-16(19-15(20)14-10-6-12-21-14)18-11-5-4-9-13-7-2-1-3-8-13/h1-3,6-8,10,12H,4-5,9,11H2,(H3,17,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107051 (CHEMBL108627 | N-(4-Methyl-benzoyl)-N'-naphthalen-...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCc1cccc2ccccc12 |w:12.13| Show InChI InChI=1S/C20H19N3O/c1-14-9-11-16(12-10-14)19(24)23-20(21)22-13-17-7-4-6-15-5-2-3-8-18(15)17/h2-12H,13H2,1H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066430 (2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...) Show SMILES CN1CCN(CC1)c1ncc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C15H16Cl3N5/c1-22-2-4-23(5-3-22)15-20-8-11(14(19)21-15)10-6-9(16)7-12(17)13(10)18/h6-8H,2-5H2,1H3,(H2,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50107044 (CHEMBL107354 | N-(4-Methyl-benzoyl)-N'-phenethyl-g...) Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCCc1ccccc1 |w:12.13| Show InChI InChI=1S/C17H19N3O/c1-13-7-9-15(10-8-13)16(21)20-17(18)19-12-11-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H3,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
CeNeS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel				Bioorg Med Chem Lett 11: 3151-5 (2001) BindingDB Entry DOI: 10.7270/Q2PC31P4
					More data for this Ligand-Target Pair

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